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2025.03.03
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循環plus(1345-9155)23巻2号 Page2-6(2024.03)
2024/01/06
医中誌文献番号:2025032106
心血管疾患の包括的管理 残余リスク・尿酸代謝・サロゲートマーカー田中 敦史(佐賀大学 医学部循環器内科)
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日本サルコペニア・フレイル学会雑誌(2433-1805)8巻Suppl. Page139(2024.10)
2024/01/06
医中誌文献番号:2025019772
ATP再合成経路の増強作用に基づく運動機能向上剤の効果藤原 めぐみ(日本医科大学 医学部形態解析研究室), 岡本 研
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PLoS One. 2025 Jan 16;20(1):e0313562. doi: 10.1371/journal.pone.0313562. eCollection 2025.
2025/01/17
Development and validation of an interpretable machine learning model for predicting left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation patients
Huang C, Shu S, Zhou M, Sun Z, Li S.
-
Nan Fang Yi Ke Da Xue Xue Bao. 2025 Jan 20;45(1):43-51. doi: 10.12122/j.issn.1673-4254.2025.01.06.
2025/01/17
Differential expressions of exosomal miRNAs in patients with chronic heart failure and hyperuricemia: diagnostic values of miR-27a-5p and miR-139-3p
Chen Z, Yang Y, Huang X, Cheng Y, Qu Y, Heng Q, Fu Y, Li K, Gu N.
-
Int J Med Mushrooms. 2025;27(3):71-85. doi: 10.1615/IntJMedMushrooms.2024057485.
2025/01/17
Optimization of Fermentation Conditions in Ergothioneine Biosynthesis from Ganoderma resinaceum (Agaricomycetes) and an Evaluation of Their Inhibitory Activity on Xanthine Oxidase
Yu YH, Ye ZW, Huang YM, Wang N, Zheng QW, Zhong JR, Chen BX, Lin JF, Guo LQ.
-
Scand J Rheumatol. 2025 Jan 17:1-5. doi: 10.1080/03009742.2024.2421622. Online ahead of print.
2025/01/17
Elevated neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are associated with increased flares and elevated cardiovascular disease risk in gout
Stultz RD, Dai L, van Geel E, Gerritsen M, Nurmohamed MT, Lood C.
-
FASEB J. 2025 Jan 31;39(2):e70292. doi: 10.1096/fj.202401801RR.
2025/01/16
Spatiotemporal landscape of kidney in a mouse model of hyperuricemia at single-cell level
Chang H, Tao Q, Wei L, Wang Y, Tu C.
-
J Rheumatol. 2025 Jan 15:jrheum.2024-1075. doi: 10.3899/jrheum.2024-1075. Online ahead of print.
2025/01/16
Inpatient management of gout: we are still failing
Alfeld K, Barclay ML, McNeill R, Frampton C, Doogue M, Stamp LK.
-
Turk J Pediatr. 2024 Dec 30;66(6):690-702. doi: 10.24953/turkjpediatr.2024.4558.
2025/01/14
Evaluation of metabolic syndrome components, serum uric acid levels and epicardial adipose tissue thickness in pubertal children by severity of obesity
Büyükyılmaz G, Özdemir Şahan Y.
-
J Korean Med Sci. 2025 Jan 13;40(2):e1. doi: 10.3346/jkms.2025.40.e1.
2025/01/14
Effects of Genetic Risk and Lifestyle Habits on Gout: A Korean Cohort Study
Kim H, Do H, Son CN, Jang JW, Choi SS, Moon KW.
-
Foods. 2024 Dec 28;14(1):58. doi: 10.3390/foods14010058.
2025/01/11
Investigating the Role of Food-Derived Peptides in Hyperuricemia: From Mechanisms of Action to Structural Effects
Han Y, Liu W, Li K, Zhang M, Liu X, Li L, Guo Z, Li H.
-
Foods. 2024 Dec 27;14(1):46. doi: 10.3390/foods14010046.
2025/01/11
Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources
Mititelu M, Lupuliasa D, Neacșu SM, Olteanu G, Busnatu ȘS, Mihai A, Popovici V, Măru N, Boroghină SC, Mihai S, Ioniță-Mîndrican CB, Scafa-Udriște A.
-
Int J Mol Sci. 2025 Jan 5;26(1):404. doi: 10.3390/ijms26010404.
2025/01/11
Theoretical Study of Antioxidant and Prooxidant Potency of Protocatechuic Aldehyde
Amić A, Mastiľák Cagardová D, Milanović Ž.
-
Endocrinol Diabetes Nutr (Engl Ed). 2025 Jan;72(1):26-36. doi: 10.1016/j.endien.2024.12.005.
2025/01/11
Reducing hyperuricemic events with SGLT2 inhibitors: An updated systematic review with meta-regression
Ghukasyan H, Pedro Navalha DD, Pérez Romero I, Prato Wolwacz MV, Ghahramanyan A, Tsing Ngan CW, Siqueira Tavares de Melo MH, Serafim Dagostin C, Gómez-Lechón Quirós L.
-
Rheumatology (Oxford). 2025 Jan 10:keaf017. doi: 10.1093/rheumatology/keaf017. Online ahead of print.
2025/01/10
Treatment-Emergent Major Adverse Cardiovascular and Thromboembolic Events were Infrequent During Clinical Trials of Pegloticase
Troum OM, Duong M, Obermeyer K, Padnick-Silver L, LaMoreaux B.
-
Org Lett. 2025 Jan 10;27(1):421-426. doi: 10.1021/acs.orglett.4c04391. Epub 2024 Dec 30.
2025/01/10
Discovery, Characterization, and Anti-XOD Activity of Calcium Metallophore from Coix lacryma-jobi
Xue Y, Song D, Liu SR, Lei CW, Shi H, Zhou Y, Feng TT, Wei X.
-
BMC Public Health. 2025 Jan 9;25(1):116. doi: 10.1186/s12889-025-21360-z.
2025/01/10
Association between the screen time spent watching short videos at bedtime and essential hypertension in young and middle-aged people: a cross-sectional study
Li F, Ma F, Liu S, Wang L, Ji L, Zheng M, Liu G.
-
Sci Rep. 2025 Jan 9;15(1):1525. doi: 10.1038/s41598-025-85848-9.
2025/01/10
Oatmeal and wheat flour as the sources of thyroid peroxidase and proinflammatory enzymes modulators in the prevention of thyroid diseases
Gawlik U, Habza-Kowalska E, Piwowarczyk K, Czyż J, Złotek U.
-
Anal Chim Acta. 2025 Jan 22;1336:343522. doi: 10.1016/j.aca.2024.343522. Epub 2024 Dec 4.
2025/01/10
Wood membrane: A sustainable electrochemical platform for enzyme-free and pretreatment-free monitoring uric acid in bodily fluids
Zhao J, Guo J, Li J, Zhao C, Gao Z, Song YY, Li X.
-
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Aug 28;49(8):1175-1186. doi: 10.11817/j.issn.1672-7347.2024.240394.
2025/01/10
Machine learning-driven risk assessment of coronary heart disease: Analysis of NHANES data from 1999 to 2018
Lu J, Hu H, Xiu J, Yang Y, Zhu Q, Dai H, Liu X, Wang J.
-
Int J Biol Macromol. 2025 Jan 7;295:139606. doi: 10.1016/j.ijbiomac.2025.139606. Online ahead of print.
2025/01/10
Exploring the separation, characterization and antioxidant activity of proteins and peptides from selected seagrasses in Palk Bay region of Tamil Nadu in India
Arya R, Abinaya K, Meenakumari S, Thirumavalavan M, Velmurugan D, Anbu P, Pachaiappan R.
-
ACS Sens. 2025 Jan 24;10(1):159-174. doi: 10.1021/acssensors.4c01595. Epub 2025 Jan 9.
2025/01/09
Plug-In Design of the Microneedle Electrode Array for Multi-Parameter Biochemical Sensing in Gouty Arthritis
Liu Z, Huang X, Liu Z, Zheng S, Yao C, Zhang T, Huang S, Zhang J, Wang J, Farah S, Xie X, Chen HJ.
-
Curr Med Chem. 2025 Jan 7. doi: 10.2174/0109298673320456241024053452. Online ahead of print.
2025/01/09
Therapeutic Effects of Tea Polyphenols on Renal Damage Induced by High Uric Acid
Liu L, Shuai L, He S, Xiang W, He X.
-
Cureus. 2024 Dec 9;16(12):e75394. doi: 10.7759/cureus.75394. eCollection 2024 Dec.
2025/01/09
Hyperuricemia Is Associated With Higher Mortality in Non-diabetic Heart Failure Patients
Madureira S, Gouveia R, Elias C, Neves A, Ribeirinho-Soares P, Amorim M, Soares M, Pereira J, Almeida J, Lourenço P.
-
J Inflamm Res. 2025 Jan 3;18:17-30. doi: 10.2147/JIR.S500101. eCollection 2025.
2025/01/09
Tigulixostat Alleviates Hyperuricemic Nephropathy by Promoting M2 Macrophage Polarization
Xue L, Tao Q, Chang H, Yan S, Wang L, Zhao Z, Tu C.
-
Food Res Int. 2025 Jan;200:115310. doi: 10.1016/j.foodres.2024.115310. Epub 2024 Dec 11.
2025/01/09
The influence of temperature induced changes in the composition of MFGM on membrane phase transition and nanomechanical properties
Pan R, Huang Y, Wei T, Zheng L, Hu Z, Duan J, Hao X, Deng Z, Li J.
-
Chem Biodivers. 2025 Jan 8:e202402104. doi: 10.1002/cbdv.202402104. Online ahead of print.
2025/01/09
New Pyranopyrazole-Based Indolin-2,3-Dione Hybrid as Effective Inhibitors of Xanthine Oxidase: Synthesis, In Vitro, and Molecular Modeling Approaches
Alharbi O, Al-Mutairi KA, Ibrahim MM, Ramu R, Al-Ghorbani M.
-
J Nephrol. 2025 Jan 8. doi: 10.1007/s40620-024-02179-0. Online ahead of print.
2025/01/08
Association between urate-lowering therapy and kidney failure in patients with chronic kidney disease
Mouheb A, Lambert O, Alencar de Pinho N, Jacquelinet C, Laville M, Combe C, Fouque D, Frimat L, Massy ZA, Laville SM, Liabeuf S; Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) Study Group.
-
Folia Med (Plovdiv). 2024 Dec 31;66(6):929-934. doi: 10.3897/folmed.66.e126615.
2025/01/08
DRESSed for distress: a case of allopurinol-induced DRESS syndrome
Kalfoutzou A, Doumana A, Karamolegkou AI, Mylonakis A, Piperis C, Dimitrakoudi M, Mostratou E.
-
Nutrients. 2024 Dec 12;16(24):4301. doi: 10.3390/nu16244301.
2025/01/08
Preparation and Efficacy Evaluation of Antihyperuricemic Peptides from Marine Sources
Qiao K, Huang Q, Sun T, Chen B, Huang W, Su Y, Lin H, Liu Z.
-
Pharmaceuticals (Basel). 2024 Nov 23;17(12):1575. doi: 10.3390/ph17121575.
2025/01/08
Evaluation of Dactylopius opuntiae Extract for Xanthine Oxidase Inhibition and Serum Uric Acid Reduction in a Hyperuricemic Mouse Model
Aragon-Martinez OH, González-Chávez MM, Galicia-Cruz OG, Méndez-Gallegos SJ, Isiordia-Espinoza MA, Martinez-Morales F.
-
Medicina (Kaunas). 2024 Nov 26;60(12):1943. doi: 10.3390/medicina60121943.
2025/01/08
Correlation of the FIB-4 Liver Biomarker Score with the Severity of Heart Failure
Buzas R, Ciubotaru P, Faur AC, Preda M, Ardelean M, Georgescu D, Dumitrescu P, Lighezan DF, Popa MD.
-
J Clin Med. 2024 Dec 13;13(24):7616. doi: 10.3390/jcm13247616.
2025/01/08
Gout and Hyperuricemia: A Narrative Review of Their Comorbidities and Clinical Implications
Timsans J, Palomäki A, Kauppi M.
-
Life (Basel). 2024 Dec 18;14(12):1682. doi: 10.3390/life14121682.
2025/01/08
Effect of Metformin on Meibomian Gland Epithelial Cells: Implications in Aging and Diabetic Dry Eye Disease
Rescher L, Singh S, Zahn I, Paulsen F, Schicht M.
-
Biomolecules. 2024 Nov 29;14(12):1530. doi: 10.3390/biom14121530.
2025/01/08
Urate Levels as a Predictor of the Prevalence and Level of Cardiovascular Risk Factors: An Identificación de La PoBlación Española de Riesgo Cardiovascular y Renal Study
Antelo-Pais P, Prieto-Díaz MÁ, Micó-Pérez RM, Pallarés-Carratalá V, Velilla-Zancada S, Polo-García J, Barquilla-García A, Ginel-Mendoza L, Segura-Fragoso A, Vitelli-Storelli F, Martín-Sánchez V, Hermida-Ameijerias Á, Cinza-Sanjurjo S, On Behalf Of The Investigators Of The Iberican Study And Of The Spanish Society Of Primary Care Physicians Semergen Foundation.
-
Biomolecules. 2024 Nov 28;14(12):1527. doi: 10.3390/biom14121527.
2025/01/08
Success of an Inpatient Rehabilitation Program in Subjects with Type 2 Diabetes Mellitus with or Without Metabolic Syndrome
Thauerer B, Odrovicsné Tóth A, Salzer A, Steinecker-Frohnwieser B.
-
Antioxidants (Basel). 2024 Nov 22;13(12):1439. doi: 10.3390/antiox13121439.
2025/01/08
Potential Opportunities for Pharmacogenetic-Based Therapeutic Exploitation of Xanthine Dehydrogenase in Cardiovascular Disease
Massimo G, Dyson N, Olotu F, Khambata RS, Ahluwalia A.
-
Rheumatology (Oxford). 2025 Jan 6:keae719. doi: 10.1093/rheumatology/keae719. Online ahead of print.
2025/01/06
Correction to: Non-adherence to urate lowering therapy in gout after 5 years is related to poor outcomes: results from the NOR-Gout study
-
Curr Med Chem. 2025 Jan 2. doi: 10.2174/0109298673325682241114162014. Online ahead of print.
2025/01/06
Oxidative Stress Biomarkers in Hypertension
Fountoulakis P, Kourampi I, Theofilis P, Marathonitis A, Papamikroulis GA, Katsarou O, Marinos G, Oikonomou E, Siasos G, Tousoulis D.
-
Zhonghua Yi Xue Za Zhi. 2025 Jan 7;105(1):63-71. doi: 10.3760/cma.j.cn112137-20240814-01866.
2025/01/06
[Influencing factors analysis and prediction model establishment of toe-amputation in patients with diabetic foot]
Zhu D, Chen Y, Yang CZ, Zhao JY, Sun YC, Wang LC, Chen HM, Xiao L, Li J.
-
Brain Res. 2025 Feb 15;1849:149444. doi: 10.1016/j.brainres.2025.149444. Epub 2025 Jan 2.
2025/01/05
A non-purine inhibitor of xanthine oxidoreductase mitigates adenosine triphosphate degradation under hypoxic conditions in mouse brain
Sato N, Kusano T, Nagata K, Okamoto K.
-
BMC Musculoskelet Disord. 2025 Jan 3;26(1):14. doi: 10.1186/s12891-024-08264-6.
2025/01/04
Association between obstructive sleep apnea and hyperuricemia/gout in the general population: a cross-sectional study
Park S, Bak SH, Kim HS, Lee KA.
-
J Med Internet Res. 2024 Dec 30;26:e58686. doi: 10.2196/58686.
2025/01/04
Development and Validation of a Nomogram-Based Model to Predict Primary Hypertension Within the Next Year in Children and Adolescents: Retrospective Cohort Study
Qin C, Peng L, Liu Y, Zhang X, Miao S, Wei Z, Feng W, Zhang H, Wan C, Yu Y, Lu S, Huang R, Zhang X.
-
Bioorg Chem. 2025 Jan;154:108108. doi: 10.1016/j.bioorg.2024.108108. Epub 2024 Dec 30.
2025/01/04
Discovery of cyanidin-3-O-galactoside as a novel CNT2 inhibitor for the treatment of hyperuricemia
Zheng F, Ke J, Lin S, Ye W, Wu Z, Xu Y, Mai S, Chen Y, Guo Z, Hu H, Zhang S, Pang J, Zhang Q, Zhao Z.
-
Diabetes Obes Metab. 2025 Jan 2. doi: 10.1111/dom.16165. Online ahead of print.
2025/01/03
Risk acceleration by gout on major adverse cardiovascular events and all-cause death in patients with diabetes and chronic kidney disease
Lee DY, Moon JS, Jung I, Chung SM, Park SY, Yu JH, Seo JA, Han KD, Kim NH.
-
Arthritis Care Res (Hoboken). 2025 Jan 2. doi: 10.1002/acr.25494. Online ahead of print.
2025/01/03
Relationship Between Gout Flare States and Patient-Reported Outcomes After Allopurinol Initiation
Stamp LK, Frampton C, Stewart S, Petrie KJ, Edwards NL, Gaffo A, Dalbeth N.
-
Sci Rep. 2025 Jan 2;15(1):97. doi: 10.1038/s41598-024-83831-4.
2025/01/03
U-shaped relationship between uric acid levels and all-cause mortality in patients with hypertension
Huang Y, Li J, Sun F, Zhou H, Jiang H, Chen L.
-
Front Med (Lausanne). 2024 Dec 18;11:1486611. doi: 10.3389/fmed.2024.1486611. eCollection 2024.
2025/01/02
Association between waist-to-height ratio and osteoporosis in the National Health and Nutrition Examination Survey: a cross-sectional study
Li H, Qiu J, Gao Z, Li C, Chu J.
-
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2024 Dec;32(6):1764-1770. doi: 10.19746/j.cnki.issn.1009-2137.2024.06.020.
2025/01/02
[Prognostic Value and Threshold Effect of Serum C3, C4 in Patients with Multiple Myeloma]
Zhang T, Yin LS, Yang MM.
-
Int J Biol Macromol. 2024 Dec 30;293:139373. doi: 10.1016/j.ijbiomac.2024.139373. Online ahead of print.
2025/01/02
Effects and mechanisms of theabrownin from black tea in improving hyperuricemia: Evidence from animal study and clinical trial
Ding X, Yuan Q, Han C, Shen C, Chen M, Yin H, Zhong H, Yang C, Huang J, He C, Zuo Z.
-
Int J Biol Macromol. 2024 Dec 30;293:139370. doi: 10.1016/j.ijbiomac.2024.139370. Online ahead of print.
2025/01/02
Anti-hyperuricemia effects of a polysaccharide-protein complex from Lentinula edodes mediated by gut-kidney axis
Xiong X, Liu P, Liu L, Feng J, Zhang J, Yan M, Liu Y.
-
Cardiovasc Ther. 2024 Jul 4;2024:5945687. doi: 10.1155/2024/5945687. eCollection 2024.
2025/01/01
Off-Pump Coronary Artery Bypass Graft (OCABG) Surgery Outcome: AKI Incidence, Serum Uric Acid, and Cut-Offs of Variables
Zare-Khormizi MR, Pourrajab F.
-
Phytochem Anal. 2024 Dec 30. doi: 10.1002/pca.3485. Online ahead of print.
2025/01/01
Fast and Efficient Screening and Separation Based on AUF-MS Combined With Molecular Docking Technology and Network Pharmacology Method for Potential Xanthine Oxidase Inhibitors From Pinelliae Rhizoma Praeparatum
Liu Q, Nong Y, Li S, Zhou Y, Liu X, Liu D, Li Y.
-
Int J Rheum Dis. 2025 Jan;28(1):e70034. doi: 10.1111/1756-185X.70034.
2025/01/01
hURAT1 Transgenic Mouse Model for Evaluating Targeted Urate-Lowering Agents
Cai W, Yang M, Zhao Q, Yi G, Lin P, Chen A, De G.