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新着論文
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BMC Oral Health. 2025 Apr 30;25(1):669. doi: 10.1186/s12903-025-06024-z.
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Study on the potential links between clinical features of oral lichenoid mucositis and systemic diseases
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BMJ Open. 2025 Apr 29;15(4):e094857. doi: 10.1136/bmjopen-2024-094857.
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Association of hyperuricaemia and hyperglycaemia with risk of in-hospital mortality in acute aortic dissection: a multicentre cohort study in the Han Chinese population
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Biomed Pharmacother. 2025 Jun;187:118086. doi: 10.1016/j.biopha.2025.118086. Epub 2025 Apr 29.
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Febuxostat alleviate metabolic dysfunction-associated steatohepatitis in rat model via targeting inflammation, cell death, and intestinal barrier dysfunction
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Eur J Med Chem. 2025 Aug 5;292:117649. doi: 10.1016/j.ejmech.2025.117649. Epub 2025 Apr 17.
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Structure optimization of natural product piperine to obtain novel and potent analogs with anti-inflammation pain and urate-lowering effect
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Photochemical transformation of the uricosuric drug benzbromarone in aqueous solutions exposed to UV irradiation
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ADMET DMPK. 2025 Jan 23;13(2):2601. doi: 10.5599/admet.2601. eCollection 2025.
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Management of intraocular pressure and inflammation using febuxostat film: in vitro - in vivo correlation
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Endocrinol Diabetes Metab. 2025 May;8(3):e70055. doi: 10.1002/edm2.70055.
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Food Chem. 2025 Sep 1;485:144458. doi: 10.1016/j.foodchem.2025.144458. Epub 2025 Apr 26.
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Rosmarinic acid in Perilla frutescens L. as a potential adenosine deaminase inhibitor: Preparation, machine learning validation and binding mechanism study
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Medicine (Baltimore). 2025 May 2;104(18):e42377. doi: 10.1097/MD.0000000000042377.
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Factors associated with hyperhomocysteinemia in relatively healthy adult males in northern Shaanxi, China: A cross-sectional study
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Rapid Commun Mass Spectrom. 2025 Aug 15;39(15):e10035. doi: 10.1002/rcm.10035.
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Serum uric acid levels as a causal factor in hypertension: Insights from Mendelian randomization analysis
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Kardiologiia. 2025 Apr 30;65(4):23-30. doi: 10.18087/cardio.2025.4.n2919.
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Long-Term Prospective Observation Study of Patients with Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases
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Cureus. 2025 Apr 5;17(4):e81773. doi: 10.7759/cureus.81773. eCollection 2025 Apr.
2025/05/07
Excessively Low Insulin Resistance May Increase the Risk of All-Cause Mortality Among Community-Dwelling Individuals Without Diabetes
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Adv Ther. 2025 May 8. doi: 10.1007/s12325-025-03189-5. Online ahead of print.
2025/05/08
Evaluation of Real-World Treatment Patterns and Healthcare Resource Utilization in Patients with Chronic Refractory Gout in the United States
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Front Pharmacol. 2025 Apr 23;16:1519054. doi: 10.3389/fphar.2025.1519054. eCollection 2025.
2025/05/08
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BMC Public Health. 2025 May 7;25(1):1685. doi: 10.1186/s12889-025-22924-9.
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Association of chronic kidney disease and cardiovascular disease risk with all-cause mortality: an interaction, joint and mediation analysis in Chinese adults
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Metabolomics. 2025 May 7;21(3):60. doi: 10.1007/s11306-025-02261-z.
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Volatile organic compound exposure is associated with hyperuricemia in the general population: an analysis of 6878 adults from the NHANES
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Naunyn Schmiedebergs Arch Pharmacol. 2025 May 8. doi: 10.1007/s00210-025-04237-1. Online ahead of print.
2025/05/08
NDUFA8 promotes cell viability and inhibits ferroptosis and cisplatin sensitivity by stabilizing Fe-S clusters in cervical cancer
Xiang H, Sun J, Kong L, Wang Y, Qiu X, Zeng J, Li G, He J.
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J Sci Food Agric. 2025 May 9. doi: 10.1002/jsfa.14341. Online ahead of print.
2025/05/09
Comparison of the anti-hyperuricemia effects of several cinnamic acid derivatives
Sun J, Shen Z, Sun Y, You Y, Zhu C, Cheng S, Yu G, Yang Y, Tang Z.
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Thorac Cancer. 2025 May;16(9):e70076. doi: 10.1111/1759-7714.70076.
2025/05/09
Association of Baseline Serum Uric Acid With Venous Thromboembolism and Clinical Outcomes in Patients With Non-Small Cell Lung Cancer
Zhang XL, Zhang C, Lang L, Yi JW, Zhu M, Zhang YH.
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Front Cardiovasc Med. 2025 Apr 24;12:1570239. doi: 10.3389/fcvm.2025.1570239. eCollection 2025.
2025/05/09
Association of triglyceride-glucose-related indices with adverse clinical outcomes in individuals with normal body mass index
Xie J, Pei X, Zhu S, Jiang W, Tang H, Wu D, Xie Y.
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Turk J Med Sci. 2025 Jan 8;55(2):413-422. doi: 10.55730/1300-0144.5985. eCollection 2025.
2025/05/09
Evaluation of treatment compliance in gout patients: a patient-centered study
Görgülü MB, Kardaş RC, Şeramet DK, Mercan R, Tezcan ME, Tufan A, Küçük H, Göker B, Öztürk MA.
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ACS Synth Biol. 2025 May 8. doi: 10.1021/acssynbio.4c00831. Online ahead of print.
2025/05/09
Systematic Engineering for Efficient Uric Acid-Degrading Activity in Probiotic Yeast Saccharomyces boulardii
Wang W, Pan L, He H, Xue H, Huang H, Samosir AM, Fu X, Shen Y.
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Eur J Clin Pharmacol. 2025 May 10. doi: 10.1007/s00228-025-03848-0. Online ahead of print.
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Purine xanthine oxidase inhibitors are not conducive to the prognosis of chronic heart failure: a meta-analysis
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Indian J Nephrol. 2025 May-Jun;35(3):368-372. doi: 10.25259/IJN_31_2024. Epub 2024 Jul 22.
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Prevalence and Association of Insulin Resistance in Non-Diabetic Hemodialysis Patients: A Descriptive-Analytic Cross-Sectional Study in Vietnam
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Front Chem. 2025 Apr 25;13:1576852. doi: 10.3389/fchem.2025.1576852. eCollection 2025.
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Chemical profile of Rhododendron luteum Sweet leaf supercritical CO(2) extracts and their anti-inflammatory and antidiabetic potential
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Front Pharmacol. 2025 Apr 25;16:1576390. doi: 10.3389/fphar.2025.1576390. eCollection 2025.
2025/05/12
Chromene flavanones from Dalea boliviana as xanthine oxidase inhibitors: in vitro biological evaluation and molecular docking studies
Bedoya Aguirre EN, Santi MD, Negro MF, Echeverría J, Paulino Zunini M, Peralta MA, Ortega MG.
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Circ J. 2025 May 23;89(6):793-802. doi: 10.1253/circj.CJ-24-0931. Epub 2025 May 11.
2025/05/12
Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation - Longitudinal Cohort Study
Liu L, Li L, Cai S, Chen A, Xu M, Dong Y, Zhou L, Li Y, Lu M, Zheng L, Ding L, Fan X, Yao Y.
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Chin J Integr Med. 2025 May 13. doi: 10.1007/s11655-025-4133-1. Online ahead of print.
2025/05/13
Hydroxychavicol in Combination with 5-Fluorouracil Induced Apoptosis by Inhibiting Purine Metabolism in HT-29 and DLD-1 Cell Lines
Mohamad NA, Rahman AA, Kadir SHSA, Naes SM, Mazlan M, Makpol S.
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Dermatologie (Heidelb). 2025 May 13. doi: 10.1007/s00105-025-05499-9. Online ahead of print.
2025/05/13
[Miliary palmoplantar gout tophi in a patient with hyperuricemia and chronic renal insufficiency]
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J Pharm Biomed Anal. 2025 May 9;264:116919. doi: 10.1016/j.jpba.2025.116919. Online ahead of print.
2025/05/14
Comprehensive high-throughput screening and efficient preparation of active components of Ganoderma resinaceum and in vitro evaluation of therapeutic effect on gout
Nong Y, Shi D, Li S, Chen Z, Zhang Y, Liang J, Zhang Y.
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Ugeskr Laeger. 2025 May 5;187(19):V11240823. doi: 10.61409/V11240823.
2025/05/14
[Untreated arthritis urica can cause foot ulcers and amputations in patients with diabetes]
Jensen MCH, Risgaard B, Wolf HT.
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Front Pharmacol. 2025 Apr 29;16:1563676. doi: 10.3389/fphar.2025.1563676. eCollection 2025.
2025/05/14
Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins
Li N, Liu H, Song Z, Zhou R, Tang Z, Xu H, Shi X, Liu Y, Ni J.
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Front Vet Sci. 2025 Apr 29;12:1587004. doi: 10.3389/fvets.2025.1587004. eCollection 2025.
2025/05/14
Effects of dietary protein sources and levels on uric acid metabolism, renal function, and inflammatory responses in goslings
Chen Y, Yang Z, Su G, Li N, Yang H, Wang Z.
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J Clin Med. 2025 Apr 29;14(9):3088. doi: 10.3390/jcm14093088.
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Sex- and Stage-Specific Predictors of Anemia in Chronic Kidney Disease: A Retrospective Cohort Study
Chang JT, Lin CJ, Yeh JH, Tsai CH, Hsieh IS, Chang PY.
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Nutrients. 2025 May 6;17(9):1596. doi: 10.3390/nu17091596.
2025/05/14
Anti-Hyperuricemic and Nephroprotective Effects of Hydrolysate Derived from Silkworm Pupae (Bombyx mori): In Vitro and In Vivo Study
Fan Y, Yang Z, Lin X, Xu Z, Mu L, Li Q, Wu X.
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Int J Mol Sci. 2025 May 3;26(9):4360. doi: 10.3390/ijms26094360.
2025/05/14
Association Between Periodontal Pathogens and Inflammation in Patients with Acute Coronary Syndromes
Rodean IP, Halațiu VB, Popa TM, Blîndu E, Mihăilă T, Țolescu C, Modiga A, Benedek I, Benedek T.
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Nutr Metab (Lond). 2025 May 13;22(1):43. doi: 10.1186/s12986-025-00930-3.
2025/05/14
Sex differences in the associations between prior weight loss and all-cause or cardiovascular mortality in non-elderly individuals with hyperuricemia: a mortality follow-up study
Li Y, Kong X, Wang W.
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Mol Med. 2025 May 13;31(1):184. doi: 10.1186/s10020-025-01246-x.
2025/05/14
JAK2/STAT3/HMGCS2 signaling aggravates mitochondrial dysfunction and oxidative stress in hyperuricemia-induced cardiac dysfunction
Peng D, He X, Ren B, Wang Q, Peng L, Jiang Y, Huo S, Men L, Shi W, Luo P, Zhu M, Zhang C, Lv J, Lin L, Li S.
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BMC Cardiovasc Disord. 2025 May 13;25(1):363. doi: 10.1186/s12872-025-04825-2.
2025/05/14
Early detection of left atrial dysfunction in young hypertensive patients with a normal left atrial size: a comprehensive analysis using four-dimensional auto left atrial quantification echocardiography
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Sci Rep. 2025 May 13;15(1):16625. doi: 10.1038/s41598-025-00765-1.
2025/05/14
Associations of serum uric acid to eGFR ratio with diabetic retinopathy in individuals with type 2 diabetes
Nie C, Ma Q, Liu C, Chen L, Wang C, Hou X.
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Urol Pract. 2025 May 15:101097UPJ0000000000000829. doi: 10.1097/UPJ.0000000000000829. Online ahead of print.
2025/05/15
Health Care Spending Associated With Preventative Pharmacologic Therapy for Urolithiasis
Sui W, Hollingsworth JM, Oerline MK, Hsi RS, Crivelli JJ, Best SL, Shahinian VB.
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Transplant Direct. 2025 May 12;11(6):e1803. doi: 10.1097/TXD.0000000000001803. eCollection 2025 Jun.
2025/05/15
Monosodium Urate Crystal Depletion and Bone Erosion Response in Kidney Transplant Recipients With Uncontrolled Gout Treated With Pegloticase: PROTECT Serial Dual-Energy Computed Tomography Findings
Dalbeth N, Abdellatif A, Botson JK, Saag KG, Kumar A, Padnick-Silver L, Vranic Z, Marder BA, Becce F.
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Life Med. 2025 Mar 31;4(2):lnaf014. doi: 10.1093/lifemedi/lnaf014. eCollection 2025 Apr.
2025/05/15
Identification of deferasirox as a human xanthine oxidase inhibitor
Qi Y, He X, Wu X, Zhou T, Liang N, Jiao J, Chen Y, Yuan Y, Zhang Y, Wang Y, Liu Y, Ding Q.
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Diabetes Res Clin Pract. 2025 May 13;225:112246. doi: 10.1016/j.diabres.2025.112246. Online ahead of print.
2025/05/16
Genetically proxied glucokinase activation and risk of diabetic complications: Insights from phenome-wide and multi-omics mendelian randomization
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Arch Med Res. 2025 May 14;56(6):103235. doi: 10.1016/j.arcmed.2025.103235. Online ahead of print.
2025/05/16
Single Nucleotide Variants of the SLC2A9 Gene are Associated With Hyperuricemia in Mexican Patients With Type 2 Diabetes
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Stud Health Technol Inform. 2025 May 15;327:452-456. doi: 10.3233/SHTI250378.
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BMC Public Health. 2025 May 17;25(1):1818. doi: 10.1186/s12889-025-22484-y.
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【改訂版 同効薬、納得の使い分けUpdate 最新の根拠を学び、症例で鍛え、ピットフォールを回避する】(第5章)糖尿病・内分泌代謝の薬の使い分け 痛風・高尿酸血症の薬の使い分け熊谷 天哲(阪急伊丹くまがい内科皮膚科), 内田 俊也
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J Agric Food Chem. 2025 May 19. doi: 10.1021/acs.jafc.5c01260. Online ahead of print.
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Galangin Protects against Hyperuricemia via Ameliorating Gut-Kidney Axis Dysfunction in Mice
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Chem Biodivers. 2025 May 19:e202500328. doi: 10.1002/cbdv.202500328. Online ahead of print.
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Enzyme Inhibitory and Antioxidant Potential with Phytochemical Analysis of Satureja hasturkii H.Duman & Dirmenci: A New Record From Türkiye
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J Med Biochem. 2025 Mar 21;44(2):227-234. doi: 10.5937/jomb0-52077.
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Shear wave elastography to evaluate the effect of serum uric acid levels on carotid artery elasticity in patients with high-normal blood pressure
Wang Y, Wang X, Li X, Li Z, Zhang M, Zhang S, Ma L, Huang D, Li G.
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The Uric Acid to Albumin Ratio Predicts All-cause and Cardiovascular Mortality Among U.S. Adults Results from the National Health and Nutrition Examination Survey in 2003-2018
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medRxiv [Preprint]. 2025 May 11:2025.05.09.25327351. doi: 10.1101/2025.05.09.25327351.
2025/05/19
Testing for Causal Association between Serum Urate, Gout, and Prostatic Cancer in European Males
Chandrupatla SR, Sumpter N, Takei R, Merriman TR, Singh JA.
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medRxiv [Preprint]. 2025 May 11:2025.05.10.25327361. doi: 10.1101/2025.05.10.25327361.
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Markers of Inflammation are Associated with Symptoms and Neighborhood Deprivation in Black Adults with Heart Failure
Butts B, Herring C, Madariaga A, Graven LJ, Higgins MK, Dunbar SB.
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Neurosurg Rev. 2025 May 19;48(1):424. doi: 10.1007/s10143-025-03588-w.
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Serum uric acid is associated with shunt dependent hydrocephalus of aneurysmal subarachnoid hemorrhage patients
Wang R, Zhang J, Xu J, He M.
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Carbohydr Polym. 2025 Jun 15;358:123529. doi: 10.1016/j.carbpol.2025.123529. Epub 2025 Mar 21.
2025/05/19
Structural and functional characteristics of esterified starch and microencapsulation for urate-lowering probiotic: Effect of hydrophobic side-chain length
Chen H, He J, Li W, Wang Z, Du M, Kan J.
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Int J Biol Macromol. 2025 Jun;313:144323. doi: 10.1016/j.ijbiomac.2025.144323. Epub 2025 May 16.
2025/05/19
Xanthine oxidase driven bio-Fenton system for advanced pollutant degradation in sustainable wastewater treatment
Satyam S, Patra S.
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Eur J Pharmacol. 2025 May 16;1000:177735. doi: 10.1016/j.ejphar.2025.177735. Online ahead of print.
2025/05/19
Comparative efficacy of febuxostat and vitamin E in the management of MASLD: Insights from a randomized parallel clinical study
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AIDS. 2025 May 21. doi: 10.1097/QAD.0000000000004244. Online ahead of print.
2025/05/21
Machine learning algorithms to predict the risk of hyperlipidemia in people living with HIV after starting HAART for 6 months
Ding Y, Li J, Gao C, Xing L, Sun R, Guo Y, Lv W, Fu J, Zhao Y, Li Q, Xiao J, Zhang F.
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BMC Cardiovasc Disord. 2025 May 20;25(1):386. doi: 10.1186/s12872-025-04866-7.
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Serum uric acid and coronary artery disease risk: a 10-year prospective cohort study in healthy adults
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Rheumatol Ther. 2025 May 20. doi: 10.1007/s40744-025-00767-5. Online ahead of print.
2025/05/21
Oral Urate-Lowering Therapy Use and Efficacy Following Pegloticase Treatment: Findings from a Rheumatology Network Database
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Nephron. 2025 May 20:1-10. doi: 10.1159/000546495. Online ahead of print.
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Chronic allograft injury by recurrent crystalline nephropathy of Adenine Phosphoribosyl transferase Deficiency, even after early initiation of XOR inhibitor
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Combined anticancer effects of Chamaecytisus hirsutus extract and photodynamic therapy in Gastric cancer cells
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The predictive significance of the triglyceride-glucose index in forecasting adverse cardiovascular events among type 2 diabetes mellitus patients with co-existing hyperuricemia: a retrospective cohort study
Zhao J, Li N, Li S, Dou J.
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