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新着論文
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page149(2025.01)
2024/04/01
医中誌文献番号:Z205010080
尿酸トランスポーターと高尿酸血症・痛風の薬物治療高田 龍平(東京大学医学部附属病院 薬剤部)
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page145(2025.01)
2024/04/01
医中誌文献番号:Z205010078
腎性低尿酸血症の家系に認められたURAT1 p.S508N変異とGLUT9 p.G216R変異の分子機能解析清水 聖子(防衛医科大学校 分子生体制御学講座), 豊田 優, 高田 龍平, 中山 昌喜, 四ノ宮 成祥, 松尾 洋孝
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page144(2025.01)
2024/04/01
医中誌文献番号:Z205010077
運動後急性腎不全の発症機序解明に向けたヒト尿酸トランスポーター1の分子動力学シミュレーション恒川 裕規(東京大学 大学院農学生命科学研究科), 佐藤 奈々, 永田 宏次, 岡本 研
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page142(2025.01)
2024/04/01
医中誌文献番号:Z205010075
腎尿細管における有機酸・尿酸トランスポーターOATsとジカルボン酸の相互作用池松 悠希(千葉大学 大学院医学研究院薬理学), 霊園 良恵, 大内 基司, 安西 尚彦
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page141(2025.01)
2024/04/01
医中誌文献番号:Z205010074
尿路結石症と尿酸トランスポーターABCG2の関連性の解明大橋 勇紀(名古屋大学 大学院医学系研究科総合保健学専攻ヘルスケア情報科学実社会情報健康医療学), 山口 聡, 市田 公美
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page112(2025.01)
2024/04/01
医中誌文献番号:Z205010047
フェブキソスタット40mgで血清尿酸値の治療目標値を達成できない患者へのドチヌラド0.5mg併用投与の有用性藤森 新(つばさ両国東口クリニック), 大山 博司, 諸見里 仁, 大山 恵子
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page111(2025.01)
2024/04/01
医中誌文献番号:Z205010046
尿酸生成抑制薬であるフェブキソスタットの血清尿酸値低下率は病型によって違いはない 実臨床での後方視的検討藤森 新(つばさ両国東口クリニック), 大山 博司, 諸見里 仁, 大山 恵子
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page110(2025.01)
2024/04/01
医中誌文献番号:Z205010045
高尿酸血症合併心不全急性期におけるドチヌラド使用経験水田 栄之助(労働者健康安全機構山陰労災病院), 太田原 顕, 久留 一郎
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page109(2025.01)
2024/04/01
医中誌文献番号:Z205010044
ドチヌラド抵抗性排泄低下型高尿酸血症2症例の検討 当院投与例340例中3例無効の経験から飯竹 千恵(いいたけ内科クリニック), 飯竹 一広
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page108(2025.01)
2024/04/01
医中誌文献番号:Z205010043
尿酸排泄低下型を示すXO阻害薬抵抗性高尿酸血症患者に対するドチヌラドの有効性山嵜 継敬(たちばな台クリニック 循環器内科)
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page104(2025.01)
2024/04/01
医中誌文献番号:Z205010039
URAT1におけるグリコシル化の意義ならびに関連する一塩基多型の機能探索山崎 修(帝京大学 医学部内科学講座), 藤井 航, 田村 好古, 浅川 信一郎, 細山田 真, 柴田 茂
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page101(2025.01)
2024/04/01
医中誌文献番号:Z205010036
脂肪肝と血漿中キサンチン酸化還元酵素活性の関連 人間ドック受診者における検討藏城 雅文(大阪公立大学 大学院医学研究科代謝内分泌病態内科学), 赤利 精悟, 中村 敬志
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page96(2025.01)
2024/04/01
医中誌文献番号:Z205010031
無症候性高尿酸血症を合併したCKD患者に対する尿酸降下薬の腎機能への影響高田 知朗(鳥取大学医学部附属病院)
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日本痛風・尿酸核酸学会総会プログラム・抄録集58回 Page87(2025.01)
2024/04/01
医中誌文献番号:Z205010023
非プリン型キサンチン酸化還元酵素阻害剤による低酸素条件下のマウス脳におけるATP維持効果佐藤 奈々(東京大学 大学院農学生命科学研究科応用生命化学専攻食品生物構造学研究室), 草野 輝男, 岡本 研
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Magnes Res. 2024 Dec 1;37(4):177-188. doi: 10.1684/mrh.2024.0538.
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Association between dietary magnesium intake, magnesium depletion score and hyperuricemia-related all-cause mortality or cardiovascular mortality in patients with coronary heart disease
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-
Antioxidants (Basel). 2025 Mar 14;14(3):340. doi: 10.3390/antiox14030340.
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Involvement of Oxidative Stress and Antioxidants in Modification of Cardiac Dysfunction Due to Ischemia-Reperfusion Injury
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-
Cardiovasc Ther. 2025 Mar 8;2025:2122089. doi: 10.1155/cdr/2122089. eCollection 2025.
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-
Acta Cardiol. 2025 Apr 14:1-10. doi: 10.1080/00015385.2025.2490369. Online ahead of print.
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-
Arthritis Care Res (Hoboken). 2025 Apr 14. doi: 10.1002/acr.25548. Online ahead of print.
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-
Clin Ther. 2025 Apr 12:S0149-2918(25)00085-2. doi: 10.1016/j.clinthera.2025.03.009. Online ahead of print.
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-
Zhonghua Yi Xue Za Zhi. 2025 Apr 15;105(15):1131-1135. doi: 10.3760/cma.j.cn112137-20241224-02928.
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-
Talanta. 2025 Apr 9;293:128108. doi: 10.1016/j.talanta.2025.128108. Online ahead of print.
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Bifunctional Fe-CDs@MOF composite nanozyme based ratiometric fluorescent probe for the detection of xanthine in fish
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-
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-
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Exploring the Material Basis of Taxillus chinensis in the Treatment of Hyperuricemia Nephropathy Through Absorbed Into Blood Component Analysis and Network Pharmacology
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-
Intern Med J. 2025 Apr 11. doi: 10.1111/imj.70070. Online ahead of print.
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Association between serum uric acid levels and galectin-3 in patients with uncomplicated type 2 diabetes
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-
Niger J Clin Pract. 2025 Mar 1;28(3):287-293. doi: 10.4103/njcp.njcp_252_24. Epub 2025 Apr 11.
2025/04/11
The Importance of Monocyte-to-High Density Lipoprotein-Cholesterol Ratio in Predicting Severity of Coronary Artery Disease in Acute Coronary Syndrome
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-
Front Public Health. 2025 Mar 27;13:1453700. doi: 10.3389/fpubh.2025.1453700. eCollection 2025.
2025/04/11
Clinical characteristics of pulmonary embolism at extremely high altitude: a single-center retrospective study
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-
J Biol Chem. 2025 Apr 8:108485. doi: 10.1016/j.jbc.2025.108485. Online ahead of print.
2025/04/11
GLUT2/SLC2A2 is a bi-directional urate transporter
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-
Phytomedicine. 2025 Jun;141:156676. doi: 10.1016/j.phymed.2025.156676. Epub 2025 Mar 22.
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-
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-
Front Microbiol. 2025 Mar 26;16:1555734. doi: 10.3389/fmicb.2025.1555734. eCollection 2025.
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Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia
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-
Front Nephrol. 2025 Mar 26;5:1526182. doi: 10.3389/fneph.2025.1526182. eCollection 2025.
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-
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-
Probiotics Antimicrob Proteins. 2025 Apr 9. doi: 10.1007/s12602-025-10532-3. Online ahead of print.
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Uric Acid-Degrading Lacticaseibacillus paracasei CPU202306 Ameliorates Hyperuricemia by Regulating Uric Acid Metabolism and Intestinal Microecology in Mice
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-
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Dihydromyricetin ameliorates hyperuricemia through inhibiting uric acid reabsorption
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-
Nutr Metab Cardiovasc Dis. 2025 Jun;35(6):104025. doi: 10.1016/j.numecd.2025.104025. Epub 2025 Mar 24.
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Serum uric acid fluctuations and cardiovascular outcomes in hospitalized acute heart failure patients
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-
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-
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-
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Hyperuricemia in psoriatic arthritis: clinical correlations and implications
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-
Aging Clin Exp Res. 2025 Apr 7;37(1):122. doi: 10.1007/s40520-025-03029-0.
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Association between atherogenic index of plasma, body mass index, and sarcopenia: a cross-sectional and longitudinal analysis study based on older adults in China
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-
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Amelioration of Isoproterenol-Induced Myocardial Infarction by the Phytochemical Koenigicine via Modulation of NF-κB/HO-1/NQO-1 Pathways: An In Vivo Analysis
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-
Chem Biodivers. 2025 Apr 7:e202403405. doi: 10.1002/cbdv.202403405. Online ahead of print.
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UPLC-QTOF-MS/MS Analysis, Antioxidant, Antiarthritic Potentials and Molecular Docking of Clusia rosea Jacq. Cultivated in Egypt
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-
Afr Health Sci. 2024 Dec;24(4):313-324. doi: 10.4314/ahs.v24i4.40.
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Effects of febuxostat in different doses on uric acid, inflammatory factors of serum and knee articular cavity, endothelin-1, and oxidative stress in patients with a gout-a comparative study
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-
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Structural similarity-based search for glinides exhibiting cis- and trans-inhibitory activity toward uric acid transporter 1
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-
Cell Rep. 2025 Apr 22;44(4):115514. doi: 10.1016/j.celrep.2025.115514. Epub 2025 Apr 4.
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Structural basis of urate transport by glucose transporter 9
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-
Urolithiasis. 2025 Apr 5;53(1):66. doi: 10.1007/s00240-025-01736-x.
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-
BMC Public Health. 2025 Apr 4;25(1):1278. doi: 10.1186/s12889-025-22060-4.
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The associations between serum carotenoids and hyperuricemia among U.S. National Health and Nutrition Examination Survey
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-
Clin Nephrol Case Stud. 2025 Mar 25;13:37-40. doi: 10.5414/CNCS111590. eCollection 2025.
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-
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-
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-
PLoS One. 2025 Apr 3;20(4):e0318008. doi: 10.1371/journal.pone.0318008. eCollection 2025.
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Allopurinol attenuates development of Porphyromonas gingivalis LPS-induced cardiomyopathy in mice
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-
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Pacific community's perceptions on how to improve uptake of urate-lowering therapy for Pacific gout patients
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-
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Association between allopurinol and hepatocellular carcinoma: analysis of genetic risk and patient survival
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-
Sci Rep. 2025 Apr 2;15(1):11238. doi: 10.1038/s41598-025-93680-4.
2025/04/03
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-
ARP Rheumatol. 2025 Jan-Mar;4(1):65.
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Crab-like hands as an unusual presentation of a rheumatic disease
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-
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-
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Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs
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-
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-
BMJ Case Rep. 2025 Mar 31;18(3):e262830. doi: 10.1136/bcr-2024-262830.
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Rasburicase-induced methemoglobinemia and haemolytic anaemia in a patient with G6PD deficiency
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日本内科学会雑誌(0021-5384)114巻臨増 Page166(2025.02)
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医中誌文献番号:Z306020120
尿酸血症治療薬ドチヌラドの有用性,多面的効果 開業医の多施設臨床研究岡部 富士子(おかべふじこ内科循環器クリニック), 迫村 泰成, 江藤 誠司, 岡崎 正巳, 呉 兆礼, 小西 洋之
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Heart and Vessels(0910-8327)40巻2号 Page111-122(2025.02)
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Efficacy and safety of the urate-lowering agent febuxostat in chronic heart failure patients with hyperuricemia: results from the LEAF-CHF study(タイトル和訳中)(英語)Yokota Takashi(Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University), Kinugawa Shintaro, Fukushima Arata, Okumura Takahiro, Murohara Toyoaki, Tsutsui Hiroyuki
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Modern Rheumatology(1439-7595)35巻1号 Page194-202(2025.01)
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Efficacy and safety of febuxostat in Japanese paediatric patients with hyperuricaemia including gout: Phase 2, single arm, open-label, multicentre studies(タイトル和訳中)(英語)Ito Shuichi(Department of Pediatrics, Graduate School of Medicine, Yokohama City University), Morita Yo, Nitami Makoto, Iwama Ryutaro, Nakajima Akihiro, Yamanaka Hisashi, Honda Masataka
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さかえ: 月刊糖尿病ライフ65巻2号 Page27-31(2025.02)
2024/04/16
医中誌文献番号:2025123029
メタボリックシンドロームにおけるURAT1阻害の重要性名越 智古(東京慈恵会医科大学 内科学講座循環器内科)
-
Biomolecules. 2025 Apr 1;15(4):511. doi: 10.3390/biom15040511.
2025/04/30
Probenecid Inhibits NLRP3 Inflammasome Activity and Mitogen-Activated Protein Kinases (MAPKs)
Jones LP, Martin DE, Murray J, Sancilio F, Tripp RA.
-
Chin Med J (Engl). 2025 Apr 30. doi: 10.1097/CM9.0000000000003603. Online ahead of print.
2025/04/30
Gut microbiota Lactobacillus johnsonii alleviates hyperuricemia by modulating intestinal urate and gut microbiota-derived butyrate
Han R, Wang Z, Li Y, Ke L, Li X, Li C, Tian Z, Liu X.
-
Smart Med. 2025 Apr 4;4(2):e70000. doi: 10.1002/smmd.70000. eCollection 2025 Jun.
2025/04/30
Isoliquiritigenin Promotes the Repair of High Uric Acid-Induced Vascular Injuries
Zhou H, Song X, Tian Y, Zhao L, Yang J, Ye F, Cao T, Zhang J.
-
Front Neurosci. 2025 Apr 15;19:1547010. doi: 10.3389/fnins.2025.1547010. eCollection 2025.
2025/04/30
Relations between neurometabolism and clinical biomarkers in patients with metabolic disease
Chen CC, Tan MS, Yin JT, Li JM, Li Y.
-
BMC Cardiovasc Disord. 2025 Apr 30;25(1):340. doi: 10.1186/s12872-025-04794-6.
2025/04/30
Comparison of TyG and modified TyG indices in predicting coronary slow flow phenomenon
Nan J, Meng S, Jia R, Chen W, Yang X, Hu H, Han L, Jin Z.
-
Biomedicines. 2025 Apr 3;13(4):867. doi: 10.3390/biomedicines13040867.
2025/04/29
Metabolic Alterations in Women with Lipedema Compared to Women with Lifestyle-Induced Overweight/Obesity
Jeziorek M, Wuczyński M, Sowicz M, Adaszyńska A, Szuba A, Chachaj A.
-
Antioxidants (Basel). 2025 Apr 17;14(4):483. doi: 10.3390/antiox14040483.
2025/04/29
Xanthine Oxidoreductase: A Double-Edged Sword in Neurological Diseases
Bortolotti M, Polito L, Battelli MG, Bolognesi A.
-
Diabetes Res Clin Pract. 2025 Apr 26:112204. doi: 10.1016/j.diabres.2025.112204. Online ahead of print.
2025/04/29
Metabolic crosstalk and therapeutic interplay between diabetes and hyperuricemia
Yang T, Luo L, Luo X, Liu X.
-
Nutrients. 2025 Mar 17;17(6):1052. doi: 10.3390/nu17061052.
2025/04/28
Tlalpan 2020 Case Study: Enhancing Uric Acid Level Prediction with Machine Learning Regression and Cross-Feature Selection
Gutiérrez-Esparza G, Martínez-García M, Márquez-Murillo MF, Brianza-Padilla M, Hernández-Lemus E, Amezcua-Guerra LM.
-
Clin Diabetes. 2025 Jan 6;43(2):282-290. doi: 10.2337/cd24-0082. eCollection 2025 Spring.
2025/04/28
Gout: An Overlooked Disease in Patients With Diabetes? A Danish Prospective Cohort Study With 2 Years of Follow-Up
Rasmussen C, Larsen JW, Holm PCW, Nielsen GL.
-
Nutrients. 2025 Mar 13;17(6):1013. doi: 10.3390/nu17061013.
2025/04/28
Vitamin D Status Determines Cardiometabolic Effects of Testosterone Replacement Therapy in Men with Late-Onset Hypogonadism
Krysiak R, Kowalcze K, Szkróbka W, Okopień B.
-
Eur J Med Chem. 2025 Apr 17;292:117644. doi: 10.1016/j.ejmech.2025.117644. Online ahead of print.
2025/04/27
Scaffold hopping-based structural modification of tranilast led to the identification of HNW005 as a promising NLRP3 inflammasome and URAT1 dual inhibitor for the treatment of gouty arthritis
Sun M, Lin F, Yue C, Wei Z, Liu C, Liu D, Chen X, Li Q, Liu Z, Han J, Cui Z, Mao Q, Li X, Zhang P, Zhang B, Fu X, Wang H, Mou Y, Wang S.
-
Curr Oncol Rep. 2025 Apr 26. doi: 10.1007/s11912-025-01677-z. Online ahead of print.
2025/04/26
Linking Hyperuricemia to Cancer: Emerging Evidence on Risk and Progression
Zhao L, Guo R, Zhao Z, Wang J, Lou Z, Bao J, Zheng W, Wang Q, Qiao L, Ye Y, Kwan HY, Zhou H, Wu Q, Xu K.
-
Int J Environ Res Public Health. 2025 Apr 10;22(4):594. doi: 10.3390/ijerph22040594.
2025/04/26
Association Between Area-Level Deprivation and Cardio-Metabolic Risk Factors Among the Adult Population in Russia
Zelenina AA, Shalnova SA, Drapkina OM.
-
Medicina (Kaunas). 2025 Apr 21;61(4):764. doi: 10.3390/medicina61040764.
2025/04/26
Use of Quadruple Therapy in the Management of Hypertension: A Systematic Review of Randomized Controlled Trials
Alnemer KA.
-
Medicina (Kaunas). 2025 Apr 17;61(4):740. doi: 10.3390/medicina61040740.
2025/04/26
Role of Nutritional Status in Acute Coronary Syndrome Patients with Diabetes
Seçen Ö, Uslu MF.
-
Medicina (Kaunas). 2025 Apr 17;61(4):739. doi: 10.3390/medicina61040739.
2025/04/26
Hypouricemia in Behçet's Syndrome: Prevalence and Clinical Outcomes
Oz B, Gunduz I, Karatas A, Koca SS.
-
Medicina (Kaunas). 2025 Apr 14;61(4):725. doi: 10.3390/medicina61040725.
2025/04/26
Factors Associated with Mortality Risk in Patients with Cardiogenic Shock Post-ST-Elevation Myocardial Infarction: Insights from a Regional Centre in Northwest Romania
Pop CF, Coadă CA, Lupu M, Ferenț IF, Hodas RI, Pintilie A, Ursu MŞ.
-
Genes (Basel). 2025 Apr 13;16(4):449. doi: 10.3390/genes16040449.
2025/04/26
Reduction in Liver Cancer Risk by Quercetin via Modulation of Urate Levels: Insights from Drug-Target Mendelian Randomization
Li Z, Wang Y, Yang K, Li C, Zhang M.
-
Sci Rep. 2025 Apr 24;15(1):14242. doi: 10.1038/s41598-025-99205-3.
2025/04/25
Long-term cardiovascular risk and mortality associated with uric acid to HDL-C ratio: a 20-year cohort study in adults over 40
Cui Y, Zhang W.
-
Mikrochim Acta. 2025 Apr 24;192(5):319. doi: 10.1007/s00604-025-07167-0.
2025/04/24
Preparation of immobilized xanthine oxidase with magnetic metal-organic framework and its application in screening of active ingredients in traditional Chinese medicine
Wu C, Zhang N, Li H, Wang H, Han L, Wang Y, Li F, Tian F.
-
J Food Sci. 2025 Apr;90(4):e70232. doi: 10.1111/1750-3841.70232.
2025/04/24
Skipjack Tuna (Katsuwonus pelamis) Dark Muscle Hydrolysate Ameliorates Hyperuricemia in Mice via Regulating Gut Microbiota and Serum Metabolism
Huang F, Dai Q, Ma Q, Zheng K, Wu Y, Sun D, Yu Z, Liu Y, Jiang W, Yan X.
-
Front Nutr. 2025 Apr 9;12:1561594. doi: 10.3389/fnut.2025.1561594. eCollection 2025.
2025/04/24
Association of serum uric acid-to-high-density lipoprotein cholesterol ratio with cardiovascular disease risk in patients with metabolic dysfunction-associated fatty liver disease: a cross-sectional NHANES analysis
Wang X, Shi Y, Zi Y, Long J, Shi R.
-
Mediators Inflamm. 2025 Apr 16;2025:5343213. doi: 10.1155/mi/5343213. eCollection 2025.
2025/04/24
Dynamic and Static Effects of the Systemic Inflammatory Response Index on All-Cause Mortality in Individuals With Atherosclerotic Cardiovascular Disease: Evidence From National Health and Nutrition Examination Survey
Duan C, Du Y, Chen J, Shi S, Zhang X, Hu Y.
-
J Ethnopharmacol. 2025 Apr 21:119848. doi: 10.1016/j.jep.2025.119848. Online ahead of print.
2025/04/24
Terminalia chebula Retz. extract relieves gout arthritis by inhibiting xanthine oxidase, the uric acid transporter, and NLRP3 inflammasome activation
He A, Wang J, Feng Y, Liao Z, Zheng Q, Zhang W, Chen H.
-
Int J Biol Macromol. 2025 Apr 21;310(Pt 3):143422. doi: 10.1016/j.ijbiomac.2025.143422. Online ahead of print.
2025/04/24
Alginate ameliorates hyperuricemia in mice by restoring hyperuricemia-induced renal and intestinal dysfunctions
Han R, Li Y, Guo Y, Ren M, Shan M, Mao T, Qi X, Li Y, Tian Z, Fu T.
-
Vet Sci. 2025 Mar 3;12(3):230. doi: 10.3390/vetsci12030230.
2025/04/23
Exploring the Most Effective Strategy for Purine Metabolite Quantification in Veterinary Medicine Using LC-MS/MS
Bardhi A, Dondi F, Barbarossa A.
-
Rheumatol Int. 2025 Apr 23;45(5):117. doi: 10.1007/s00296-025-05868-6.
2025/04/23
Gout and rheumatoid arthritis are associated with subclinical vascular damage, reduced brachial vasoreactivity and coronary microvascular dysfunction: a case-control study
Konal O, Bölen F, Güvenç TS, Pehlivan Ö, Batıbay S, Özcan FB, Paralı A, Aksu F, Kul Ş, Çalışkan M.
-
Med Sci (Basel). 2025 Apr 4;13(2):40. doi: 10.3390/medsci13020040.
2025/04/23
Role of IL-2, IL-6, and TNF-α as Potential Biomarkers in Ischemic Heart Disease: A Comparative Study of Patients with CAD and Non-CAD
Altyar AE, Bhardwaj S, Ghaboura N, Kaushik P, Alenezi SK, Mantargi MJS, Afzal M.
-
Food Sci Nutr. 2025 Apr 21;13(4):e70203. doi: 10.1002/fsn3.70203. eCollection 2025 Apr.
2025/04/23
Comparison of Xanthine Oxidase Inhibitory Activities and Phenolic, Fatty Acid, Element, and Vitamin Levels of Four Mushroom Species
Ekin S, Bayramoglu Akkoyun M, Bakir A, Akcay ME, Ekin EC.
-
Front Nutr. 2025 Apr 8;12:1517744. doi: 10.3389/fnut.2025.1517744. eCollection 2025.
2025/04/23
The association between serum uric acid and depression among U.S. National Health and Nutrition Examination Survey
He H, Li P, Huang H, Zeng Y, Zhang M, Chen Z, Huang S, Zeng F, Ge H.
-
Front Cardiovasc Med. 2025 Apr 8;12:1491643. doi: 10.3389/fcvm.2025.1491643. eCollection 2025.
2025/04/23
The associations between skin advanced glycation end-products and Framingham cardiovascular risk in different age groups
Wang Y, Liang S, Zhou Y, Tang X, Ye N, Huang W, Tang X, Jiang B, Pan Y.
-
Front Endocrinol (Lausanne). 2025 Apr 7;16:1504614. doi: 10.3389/fendo.2025.1504614. eCollection 2025.
2025/04/22
Uric acid-induced cardiomyocytic polyamines' insufficience: a potential mechanism mediates cardiomyocytic injury
Lin C, Zheng Q, Yu H, Wu T, Chen L, Lin W, Pang J, Yang Y.
-
Mol Med. 2025 Apr 21;31(1):144. doi: 10.1186/s10020-025-01212-7.
2025/04/22
Calpain inhibition as a novel therapeutic strategy for aortic dissection with acute lower extremity ischemia
Tan Q, Wang X, Xu W, Song K, Xiong Y, Jiang Z, Li J, Yu Y, Ye W, Shen Z, Teng X.
-
Sci Rep. 2025 Apr 21;15(1):13778. doi: 10.1038/s41598-025-98551-6.
2025/04/22
Identification of atopic dermatitis-associated diseases based on the National health and nutrition examination survey (NHANES) 2013-2018
Liu Y, Chen X, Su Z, Wang X, Wang Y, Xue Y, Li Y, Gao X, Wang L, Hao J, Wang Y, Chu M.
-
Arthritis Care Res (Hoboken). 2025 Apr 21. doi: 10.1002/acr.25556. Online ahead of print.
2025/04/21
A Consensus Based Shoulder Examination for Rheumatology Training
Degirmenci HB, Kalish R, Chopra R, Gilek-Seibert K, Koumpouras F, Kyttaris V, Lakshminarayanan S, Libman B, Mathew S, O'Rourke K, Reginato A, Kissin E.
-
Food Sci Nutr. 2025 Apr 17;13(4):e70171. doi: 10.1002/fsn3.70171. eCollection 2025 Apr.
2025/04/21
Inhibitory Effect of Whey Protein-Derived Peptide Leu-Asp-Gln-Trp on Xanthine Oxidase
Toda K, Kurimoto M, Hirose Y, Yamada A, Yuda N, Tanaka M.
-
J Adv Res. 2025 Apr 18:S2090-1232(25)00266-8. doi: 10.1016/j.jare.2025.04.022. Online ahead of print.
2025/04/21
Urate-lowering effect of delphinidin-3-glucoside in red kidney beans via binding to the FAD site of the XO enzyme
Chen Y, Jiang Y, Huang L, Li Z, Zhu M, Luo L, Zhou K, Chen M.
-
J Ethnopharmacol. 2025 Apr 18:119824. doi: 10.1016/j.jep.2025.119824. Online ahead of print.
2025/04/20
Corrigendum to "The molecular insight into the antihyperuricemic and renoprotective effect of Shuang Qi gout capsule in mice" [J. Ethnopharmacol. 163 (2015) 278-289]
Kodithuwakku ND, Feng YD, Zhang YY, Pan M, Fang WR, Li YM.
-
J Pharm Biomed Anal. 2025 Apr 11;262:116900. doi: 10.1016/j.jpba.2025.116900. Online ahead of print.
2025/04/19
Development of a fluorescence-based assay for screening of urate transporter 1 inhibitors (II): Optimization of fluorescent substrates and structure-activity relationships analysis
Dai Z, Chen H, Lu X, Cai H, Zhang L, Li J.
-
Inflammopharmacology. 2025 Apr 18. doi: 10.1007/s10787-025-01741-x. Online ahead of print.
2025/04/18
Deciphering the role of cell signaling pathways in gout pathogenesis and the therapeutic potential of phytoconstituents in their modulation
Dey H, Ali SS, Sethi VA.
-
Front Immunol. 2025 Mar 13;16:1516146. doi: 10.3389/fimmu.2025.1516146. eCollection 2025.
2025/04/18
Quality of life improvements and clinical assessments in kidney transplant recipients undergoing pegloticase treatment for uncontrolled gout: findings of the phase 4 PROTECT clinical trial
Abdellatif A, Zhao L, Obermeyer K, Vranic Z, Marder BA, Scandling JD.
-
Hepatol Forum. 2025 Jan 14;6(2):65-68. doi: 10.14744/hf.2024.2024.0027. eCollection 2025.
2025/04/18
Acute immunoallergic hepatitis due to allopurinol use
Brooks C, Calderon L, Mosunjac M, Qayed E.
-
Int J Mol Sci. 2025 Apr 5;26(7):3397. doi: 10.3390/ijms26073397.
2025/04/17
Hydrogen Peroxide: A Ubiquitous Component of Beverages and Food
Sadowska-Bartosz I, Bartosz G.
-
Int J Mol Sci. 2025 Apr 4;26(7):3376. doi: 10.3390/ijms26073376.
2025/04/17
The Clinical Utility and Plausibility of Oxidative and Antioxidant Variables in Chronic and End-Stage Kidney Disease: A Review of the Literature
Tsinari A, Roumeliotis S, Neofytou IE, Varouktsi G, Veljkovic A, Stamou A, Leivaditis K, Liakopoulos V.
-
Int J Mol Sci. 2025 Mar 27;26(7):3073. doi: 10.3390/ijms26073073.
2025/04/17
Erectile Dysfunction and Oxidative Stress: A Narrative Review
Zhu D, Pham QM, Wang C, Colonnello E, Yannas D, Nguyen BH, Zhang Y, Jannini EA, Sansone A.
-
Int J Mol Sci. 2025 Mar 26;26(7):3004. doi: 10.3390/ijms26073004.
2025/04/17
Enhancing Febuxostat Solubility Through Cocrystal Formation: Role of Substrate Selection and Amide Coformers
Pindelska E, Sarna A, Duszczyk M, Zep A, Madura ID.
-
Lipids Health Dis. 2025 Apr 16;24(1):143. doi: 10.1186/s12944-025-02551-4.
2025/04/17
Association between the uric acid-to-HDL-cholesterol ratio (UHR) and the risk of cardiovascular disease and dyslipidemia: a population-based study
Yi Y, Luo Q, Chen J, Chen Z, Aydemir HA, Chen P, Tang J, Luo F, Fang Z.
-
BMC Endocr Disord. 2025 Apr 16;25(1):99. doi: 10.1186/s12902-025-01921-4.
2025/04/17
The correlation between insulin-like growth factor 1 and left ventricular mass index in obese children
Niu W, Li C, Wang Z, Liang S.
-
Vascul Pharmacol. 2025 Apr 14:107495. doi: 10.1016/j.vph.2025.107495. Online ahead of print.
2025/04/17
Ceramide-based risk score: A novel laboratory tool for cardiovascular risk stratification in hyperuricemia and gout
Kvasnička A, Friedecký D, Piskláková B, Rozhon J, Pavelka K, Stibůrková B.
-
Foods. 2025 Mar 24;14(7):1118. doi: 10.3390/foods14071118.
2025/04/16
Protective Effects of a Polyherbal Mixture on Intestinal Injury via the NF-κB Signaling Pathway and Gut Microbiota Modulation in Hyperuricemic Mice
Wang H, Xi Y, Gu F, Peng L, Li J.
-
Curr Drug Metab. 2025 Apr 11. doi: 10.2174/0113892002368449250331144821. Online ahead of print.
2025/04/15
Expression, Function, and Regulation of ABCG2 on the Intestinal Epithelial Barrier Permeability
Shi P, Tang L, Yin F, Guo H, Liu J.
-
Comput Struct Biotechnol J. 2025 Mar 25;29:85-94. doi: 10.1016/j.csbj.2025.03.035. eCollection 2025.
2025/04/15
EthnoHERBS: Harnessing traditional herbal knowledge for biodiversity conservation and innovative health solutions
Zouraris D, Graikou K, Vasileiou P, Dimitrov V, Stevanovic ZD, Bilia AR, Zivkovic J, Dias A, Kasiotis K, Gardikis K, Dias P, Oluški M, Montaño JRM, Hristova H, Iliev H, Petrangolini G, Afantitis A, Aligiannis N.
-
Eur J Med Res. 2025 Apr 15;30(1):283. doi: 10.1186/s40001-025-02548-w.
2025/04/15
Associations of serum uric acid, risk of atherosclerotic cardiovascular disease, and mortality: results from NHANES
Chen R, Pang M, Zhang Y, Zhang H, Zhang G, Wei Y, Hua W, Zhang X, Zhang L, Li Z, Li Q, Yang P.
-
BMJ Open. 2025 Apr 14;15(4):e098096. doi: 10.1136/bmjopen-2024-098096.
2025/04/15
Design of a randomised, placebo-controlled, double-blind multicentre study assessing the effect of colchicine on the incidence of knee or hip replacements in symptomatic knee or hip osteoarthritis: the ECHO trial
Heijman MWJ, van den Ende CHM, Cornel JH, Smolders JMH, Schers HJ, Kievit W, Koeter S, van den Bemt BJF, Popa CD.