本コンテンツは、医療従事者にとって有用な学術情報をお届けすることを目的としており、
公平な立場から一定のキーワードを元に選択した高尿酸血症や痛風に関する記事をお届けしています。
一部、国内での承認外の情報が含まれることもありますが、これを推奨するものではありません。
また、特定の薬剤の処方誘引あるいは企業の営利を企図するものではありません。
治療、各薬剤の使用にあたっては最新の製品添付文書をご参照ください。
論文タイトルを押すとPubmedもしくは医中誌Webへ移動します。
※なお、医中誌Web利用には会員登録が必要になります。
新着論文
-
Journal of Atherosclerosis and Thrombosis(1340-3478)32巻4号 Page474-490(2025.04)
2025/06/16
医中誌文献番号:Z422390007
Effect of the Xanthine Oxidase Inhibitor Febuxostat on the Cardio-Ankle Vascular Index in Asymptomatic Patients with Hyperuricemia and Liver Dysfunction: A Sub-Analysis of the PRIZE Study(タイトル和訳中)(英語)Kawachi Yusuke(Department of Metabolic Medicine, Graduate School of Medicine, Osaka University), Fujishima Yuya, Nishizawa Hitoshi, Tanaka Atsushi, Yoshida Hisako, Niwano Shinichi, Suzuki Makoto, Shimomura Iichiro, Node Koichi
-
臨床皮膚科(0021-4973)79巻4号 Page341-346(2025.04)
2025/06/16
医中誌文献番号:2025189889
症例報告 手指関節部を中心に多関節に発症した痛風結節の1例眞下 修平(東邦大学 医学部皮膚科学講座(大森)), 種瀬 啓士, 横田 真樹, 三海 瞳, 海老原 椿, 鈴木 彩香, 石河 晃
-
Coron Artery Dis. 2025 Jun 17. doi: 10.1097/MCA.0000000000001544. Online ahead of print.
2025/06/16
Uric acid-to-albumin ratio × monocyte-to-lymphocyte ratio is a novel biomarker for predicting all-cause mortality and cardiovascular mortality in patients with ST-segment elevation myocardial infarction
Wei H, Zhou Y, Wang Y, Xu D, Yang Y, Shi T, Yang S, Ma X, Chen L.
-
J Pain Res. 2025 Jun 9;18:2865-2877. doi: 10.2147/JPR.S517711. eCollection 2025.
2025/06/16
Mechanistic Study on the Therapeutic Effects of Juanbi Lijieqing Formula in a Rat Model of Gouty Arthritis with Hyperuricemia
Lu Y, Lu C, Jian G, Xiong H, Shu Y.
-
Zhonghua Liu Xing Bing Xue Za Zhi. 2025 Jun 10;46(6):986-993. doi: 10.3760/cma.j.cn112338-20241225-00823.
2025/06/16
[Correlation between serum uric acid-to-high-density lipoprotein cholesterol ratio and risk of all-cause death or cardiovascular disease death in urban and rural elderly of Beijing]
Ye XX, Wang SS, Chen SM, Yang JH, Shi YT, Li HH, Bao YH, Wang WC, Du SY, Wan YH, Wang JH, Yang SS, Liu M, He Y.
-
Biochim Biophys Acta Gen Subj. 2025 Jun 13;1869(9):130833. doi: 10.1016/j.bbagen.2025.130833. Online ahead of print.
2025/06/16
The polyphenols phloretin and quercetin are potent horseradish peroxidase (HRP) inhibitors
Faerman B, Chalifoux O, Michalak M, Agellon LB, Mailloux RJ.
-
J Ethnopharmacol. 2025 Jun 13;351:120152. doi: 10.1016/j.jep.2025.120152. Online ahead of print.
2025/06/16
Network pharmacology and experimental validation reveal mechanisms of Ilicis Cornutae Folium water extract in treating hyperuricemia
Zhou X, Shi N, Ding M, Hua L, Shi S.
-
Clin Transl Sci. 2025 Jun;18(6):e70266. doi: 10.1111/cts.70266.
2025/06/13
Impact of Renal Impairment on the Pharmacodynamic and Pharmacokinetic Profiles of Epaminurad, a Novel Uric Acid Transporter 1 Inhibitor
Park SY, Hwang JG, Cho SK, Park MK.
-
Proc Natl Acad Sci U S A. 2025 Jun 17;122(24):e2422082122. doi: 10.1073/pnas.2422082122. Epub 2025 Jun 13.
2025/06/13
Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disorders
Miotto MC, Luna-Figueroa E, Tchagou C, Bahlouli L, Reiken S, Dridi H, Liu Y, Weninger G, Marks AR.
-
Front Cardiovasc Med. 2025 May 29;12:1560022. doi: 10.3389/fcvm.2025.1560022. eCollection 2025.
2025/06/13
Association between serum uric acid to high-density lipoprotein cholesterol ratio (UHR) and abdominal aortic calcification: a cross-sectional study based on NHANES 2013-2014
Li B, Xu Y, He Q, Yin Q, Wu M, Zhu H, Cao Y.
-
Molecules. 2025 Jun 3;30(11):2442. doi: 10.3390/molecules30112442.
2025/06/13
Extracts, Fractions, and Subfractions from Purple-Orange Sweet Potato (Ipomoea batatas L.): Xanthine Oxidase Inhibitory Potential and Antioxidant Properties
Suhendy H, Insanu M, Fidrianny I.
-
Int J Mol Sci. 2025 Jun 3;26(11):5355. doi: 10.3390/ijms26115355.
2025/06/13
Oxidative Stress and Endothelial Dysfunction: The Pathogenesis of Pediatric Hypertension
Backston K, Morgan J, Patel S, Koka R, Hu J, Raina R.
-
Nutrients. 2025 May 28;17(11):1844. doi: 10.3390/nu17111844.
2025/06/13
Mechanism of Ginsenoside Rg(1) in Regulating the Metabolic Function of Intestinal Flora for the Treatment of High-Purine Dietary Hyperuricemia
Sun Q, Li Z, Yu Y, Sun Y.
-
Nutrients. 2025 May 28;17(11):1831. doi: 10.3390/nu17111831.
2025/06/13
FPAW from Trachinotus ovatus Attenuates Potassium-Oxonate-Induced Hyperuricemia in Mice via Xanthine Oxidase Inhibition and Gut Microbiota Modulation: Molecular Insights and In Vivo Efficacy
Xiang H, Sun-Waterhouse D, Hu X, Hou M, Chen S, Wu Y, Zhao Y, Wang Y.
-
Diagnostics (Basel). 2025 Jun 3;15(11):1419. doi: 10.3390/diagnostics15111419.
2025/06/13
Is UA/HDL-C a Reliable Surrogate Marker for Fatty Liver? A Comparative Evaluation with Metabolic Scores in a Mexican Population: The Genetics of Atherosclerotic Disease Study
Posadas-Sánchez R, Fuentevilla-Álvarez G, Vargas-Alarcón G, Cardoso-Saldaña GC.
-
bioRxiv [Preprint]. 2025 May 31:2025.05.27.656389. doi: 10.1101/2025.05.27.656389.
2025/06/12
Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications
Liang P, Wan YS, Shan KZ, Chou R, Zhang Y, Delahunty M, Khandelwal S, Francis SJ, Arepally GM, Telen MJ, Yang H.
-
Pestic Biochem Physiol. 2025 Aug;212:106456. doi: 10.1016/j.pestbp.2025.106456. Epub 2025 May 14.
2025/06/12
Transepithelial transport and mechanism of pyrethroids across Caco-2 cells mediated by transporters
Liu Y, Zhang S, Li T, Chen C, Gui S, Liu Z, Xiao J, Cao H, Shi Y.
-
Eur J Immunol. 2025 Jun;55(6):e51176. doi: 10.1002/eji.202451176.
2025/06/11
mTOR Modulates NLRP3 Inflammasome Activation via Nuclear Translocation and STAT1 Inhibition
González-Dominguez A, Zhang S, Boy-Ruiz D, Connors D, de la Varga-Martínez R, Mock BA, Cordero MD.
-
Drug Des Devel Ther. 2025 Jun 5;19:4875-4884. doi: 10.2147/DDDT.S522154. eCollection 2025.
2025/06/11
Febuxostat Improves Postprandial Glucose Regulation and Insulin Sensitivity in Hyperuricemic Individuals with Prediabetes or Newly Diagnosed Type 2 Diabetes: A Prospective Cohort Study
Liu S, Liu Q, Gu R, Wu M, Meng S, Yan L, Chen Q, Zhu C, Chen S, Xu B, Liu F, Chen H.
-
Med Sci Monit. 2025 Jun 11;31:e947986. doi: 10.12659/MSM.947986.
2025/06/11
Predictive Scoring Model for In-Stent Restenosis Risk in Coronary Artery Disease Patients
Wang P, Xu J.
-
J Coll Physicians Surg Pak. 2025 Jun;35(6):688-692. doi: 10.29271/jcpsp.2025.06.688.
2025/06/10
Vitamin C as a Serum Uric Acid Lowering Agent in Hyperuricaemia
Siddiqui I, Khan M, Rehman F, Abbas M, Jamali S.
-
Ann Med Surg (Lond). 2025 May 21;87(6):3254-3267. doi: 10.1097/MS9.0000000000002907. eCollection 2025 Jun.
2025/06/09
Anemia and cerebrovascular disease: pathophysiological insights and clinical implications
Obeagu EI, Obeagu GU.
-
G3 (Bethesda). 2025 Jun 7:jkaf131. doi: 10.1093/g3journal/jkaf131. Online ahead of print.
2025/06/08
Human xenobiotic metabolism proteins have full-length and split homologs in the gut microbiome
Rendina M, Turnbaugh PJ, Bradley PH.
-
Cardiovasc Diabetol. 2025 Jun 6;24(1):241. doi: 10.1186/s12933-025-02790-w.
2025/06/07
Causal association of modifiable factors with cardiometabolic multimorbidity: an exposome-wide Mendelian randomization investigation
Li D, Lin J, Yang H, Zhou L, Li Y, Xu Z, Sun L, Zhang X, Xu W, Wang Y.
-
Biometals. 2025 Jun 6. doi: 10.1007/s10534-025-00699-1. Online ahead of print.
2025/06/07
Thymoquinone modulates oxidative stress and inflammation, correcting mercury-induced HO-1/NRF/Trx pathway disruption in experimental rat hepatorenal system: an in vivo and in silico study
Owumi S, Otunla M, Akindipe P, Oluwawibe B, Babalola JO, Chimezie J, Arunsi U, Owoeye O, Oyelere AK.
-
Am J Case Rep. 2025 Jun 6;26:e946972. doi: 10.12659/AJCR.946972.
2025/06/06
Crystalline Nephropathy Due to 2,8-Dihydroxyadeninuria in a Transplanted Kidney: 2 Case Reports
Raza HMA, Ibrahim A, Talwar M, Balaraman V, Bhalla A, Wall BM, Cossey LN.
-
Int Urol Nephrol. 2025 Jun 6. doi: 10.1007/s11255-025-04594-z. Online ahead of print.
2025/06/06
The effects of GLUT9 and URAT1 inhibitors on cardiovascular diseases: a drug-targeted Mendelian randomization study
Xu Q, Liang X, Shi W, Zhang H.
-
Front Physiol. 2025 May 22;16:1523940. doi: 10.3389/fphys.2025.1523940. eCollection 2025.
2025/06/06
Investigating ethylene oxide exposure and its associations with kidney indicators and lipid profiles: the mediating effect of HDL in NHANES 2013-2020
Luo Y, Xu D, Zhang W, Wang K, Kuang M, Liu Y.
-
PLoS One. 2025 Jun 5;20(6):e0325620. doi: 10.1371/journal.pone.0325620. eCollection 2025.
2025/06/05
Association between serum uric acid to high-density lipoprotein ratio and all-cause in hypertensive patients: Mediating role of neutrophils
Yan C, Zhou Y, Wang H, Fu J, Xu Q.
-
Environ Sci Technol. 2025 Jun 17;59(23):11767-11775. doi: 10.1021/acs.est.4c14351. Epub 2025 Jun 5.
2025/06/05
Occurrence and Emission Evaluation of Oxypurinol and Metformin from Effluent in WWTPs across Australia
Yang C, Zheng Q, Wang Z, Ahmed F, Tscharke B, Yang S, O'Brien JW, Verhagen R, Mueller JF, Tong L, Thai PK.
-
Front Endocrinol (Lausanne). 2025 May 21;16:1429465. doi: 10.3389/fendo.2025.1429465. eCollection 2025.
2025/06/05
Decoding the mystery between hyperuricemia and atrial fibrillation: new causal links through mediating proteomics
Zhang M, Shi L, Qin C, Peng M, Zhang Z.
-
J Microbiol. 2025 May;63(5):e2501002. doi: 10.71150/jm.2501002. Epub 2025 May 27.
2025/06/05
Microbiome therapeutic PMC72 through reverse translational research in gout
Hossain MS, Seo H, Lee KA, Ul-Haq A, Kim S, Jo S, Rahim MA, Tajdozian H, Ghorbanian F, Yoon Y, Barman I, Shuvo MSH, Kim HS, Song HY.
-
Nat Commun. 2025 Jun 4;16(1):5178. doi: 10.1038/s41467-025-60480-3.
2025/06/05
Molecular basis of the urate transporter URAT1 inhibition by gout drugs
Suo Y, Fedor JG, Zhang H, Tsolova K, Shi X, Sharma K, Kumari S, Borgnia M, Zhan P, Im W, Lee SY.
-
Food Res Int. 2025 Aug;214:116643. doi: 10.1016/j.foodres.2025.116643. Epub 2025 May 13.
2025/06/05
Preparation, identification and potential mechanism of novel urate-lowering active peptide from hemp protein: From animal model to computer simulation
Liu MQ, Zhao HF, Zhao ZY, Zhang YH, Dong Y.
-
Inflammopharmacology. 2025 Jun 4. doi: 10.1007/s10787-025-01797-9. Online ahead of print.
2025/06/04
Bee venom modulates human neutrophil inflammatory functions in Vitro and exerts an anti- inflammatory effect in Vivo in rats
Chabane MD, Bedouhene S, Belambri SA, Senani N, Rekeb T, Ladj K, Ksouri R, Dang PM, El-Benna J.
-
Front Cell Infect Microbiol. 2025 May 20;15:1582843. doi: 10.3389/fcimb.2025.1582843. eCollection 2025.
2025/06/04
Helicobacter pylori infection and apolipoprotein B/apolipoprotein A1 ratio: a cross-sectional study
Liu C, Zhu X, Pu J, Zou Z, Zhou L, Zhu X.
-
bioRxiv [Preprint]. 2025 May 12:2025.05.07.652261. doi: 10.1101/2025.05.07.652261.
2025/06/04
Liver-Derived, Circulating Xanthine Oxidoreductase Drives Vascular Impairment Associated with Inhalation of Ultrafine Particulates
Williams XM, Bossert AT, Seman M, Lewis SE, McCallen H, Pilkerton J, Bowdridge EC, Paternostro MA, Goldsmith WT, Nurkiewicz TR, Hussain S, Kelley EE, DeVallance E.
-
Plant Biol (Stuttg). 2025 Jun 3. doi: 10.1111/plb.70054. Online ahead of print.
2025/06/04
Ginkgo biloba flavonoids: Analysis of functions, regulatory mechanisms, and extraction
Wang C, Zhang W, Liao Y, Ye J, Xu F, Wang Q.
-
J Formos Med Assoc. 2025 Jun 2:S0929-6646(25)00270-0. doi: 10.1016/j.jfma.2025.05.040. Online ahead of print.
2025/06/04
Cardiovascular outcomes of febuxostat and allopurinol: A long-term Taiwanese nationwide cohort study
Yang TL, Leu HB, Lin SJ, Horng JL, Shih CM.
-
Nutr Metab Cardiovasc Dis. 2025 May 22:104161. doi: 10.1016/j.numecd.2025.104161. Online ahead of print.
2025/06/04
Uric acid to high-density lipoprotein cholesterol ratio in association with adverse health outcomes in patients with chronic kidney disease
Lei K, Hu S, Zhang Y, Wang J, Wang J.
-
Chem Biodivers. 2025 Jun 3:e00493. doi: 10.1002/cbdv.202500493. Online ahead of print.
2025/06/03
Phthalides and Norphthalides From the Ethyl Acetate Extracts of Ligusticum chuanxiong and Their Inhibitory Effects on Xanthine Oxidase In Vitro
Gao YT, Wu JF, Yang HD, Zhou R, Yang YG, Li SM, Weng JY, Liu HB, Zhu HX, Xu HB.
-
Scand J Rheumatol. 2025 Jun 3:1-9. doi: 10.1080/03009742.2025.2494378. Online ahead of print.
2025/06/03
Activation status of circulating neutrophils in gout patients
Davidsson L, Christenson K, Björkman L, Bylund J.
-
Cureus. 2025 Jun 1;17(6):e85194. doi: 10.7759/cureus.85194. eCollection 2025 Jun.
2025/06/03
The Prevalence and Associated Risk Factors of Coronary Heart Disease in Patients With Gout: A Cross-Sectional Study
Asghar S, Asghar S, Mahbub S, Riaz A, Farooq S, Khan I.
-
Commun Biol. 2025 Jun 2;8(1):845. doi: 10.1038/s42003-025-08303-5.
2025/06/03
Cathepsin B-dependent glycolysis contributes to reduced renal uric acid excretion in hyperuricemia
Lin H, Nie L, Wu D, Zhang D, Peng R, Tao S, Ye Z, Zhu S, Ye M, Xiao J.
-
Kardiologiia. 2025 Jun 2;65(5):16-20. doi: 10.18087/cardio.2025.5.n2605.
2025/06/02
Profilin as a Novel Biomarker for Assessing Atherosclerosis in Hemodialysis Patients
Güçlü A, Tur K, Jaradat Ö, Sütiçen H, Alpaslan M, Erbesler Z, Zerman A.
-
J Tehran Heart Cent. 2024 Oct;19(4):230-242. doi: 10.18502/jthc.v19i4.17606.
2025/06/02
A Systematic Review of Oxidative Stress Markers and Risk of Coronary Artery Calcification
Nazemi SS, Samadi S, Rahsepar S, Zarei B, Mohammadpour AH, Abedi F, Omidkhoda N, Sezavar M.
-
Cureus. 2025 May 2;17(5):e83332. doi: 10.7759/cureus.83332. eCollection 2025 May.
2025/06/02
Changes in Uric Acid Levels and Effects on Renal Function After Switching From Febuxostat to Dotinurad in Patients With Chronic Kidney Disease: A Retrospective Study
Mima A, Matsumoto K, Matsuki T, Morikawa T, Kure S, Akai R, Saito Y, Lee S.
-
Int Heart J. 2025;66(3):427-435. doi: 10.1536/ihj.24-220.
2025/06/02
Relationship between Uric Acid and All-Cause and Cardiovascular Mortality in Individuals with Hypertension
Gan TM, Yang Y, Mo GL, Wang SR, Li SH, Li JY.
-
治療(0022-5207)107巻6号 Page812-817(2025.05)
2025/06/16
医中誌文献番号:Z501060028
総合診療POEMs 診療で使える!旬なオススメ文献(第23回) 慢性腎臓病を伴う無症候性高尿酸血症に対して薬物療法を開始するタイミングは?岡田 悟(東京北医療センター 総合診療科), 前田 遥, 森川 暢, 井上 博人
-
J Clin Lipidol. 2025 Jun 2:S1933-2874(25)00307-1. doi: 10.1016/j.jacl.2025.05.017. Online ahead of print.
2025/06/28
Association between uric acid to high-density lipoprotein cholesterol ratio and abdominal aortic calcification: A cross-sectional study
Li Y, Bai L.
-
In Vivo. 2025 Jul-Aug;39(4):2243-2258. doi: 10.21873/invivo.14020.
2025/06/28
The Impact of Dyslipidemia on the Clinical Profile of Patients With Uncontrolled Diabetes
Paduraru L, Pascalau AV, Camarasan A, Muresan MM, Pop OL, Brata R.
-
Cureus. 2025 May 27;17(5):e84896. doi: 10.7759/cureus.84896. eCollection 2025 May.
2025/06/27
Tumor Lysis Syndrome After mFOLFOX6 Administration for Ascending Colon Cancer
Kano Y, Muranaka T, Saito W, Honma Y, Yokoyama D, Otsuka Y, Matsuda S, Takishin Y, Kunieda Y.
-
Pharmaceuticals (Basel). 2025 Jun 19;18(6):926. doi: 10.3390/ph18060926.
2025/06/27
From Ethnopharmacology to Active Compound: Effects of Traditional Plant Extracts on Varicose Vein-Related Enzymes and Isolation of Active Flavonoids from Helichrysum plicatum DC. subsp. plicatum
Buyukyildirim T, Deniz FSS, Baran MY, Salihoglu E, Yilmaz MA, Tugay O.
-
Microorganisms. 2025 Jun 12;13(6):1367. doi: 10.3390/microorganisms13061367.
2025/06/27
Triple-Probiotic-Fermented Goji (Lycium barbarum L.) Ameliorates Metabolic Disorders Associated with Hyperuricemia in Mice
Ren L, Li Y, Liu S, Jia X, He H, Zhong F, Lu F, Luo X.
-
Pediatr Nephrol. 2025 Jun 26. doi: 10.1007/s00467-025-06754-w. Online ahead of print.
2025/06/27
Effect of losartan on uric acid metabolism in children with proteinuric kidney disease: crossover randomized controlled clinical trial
Beaudoin L, Meni Battaglia L, Martin SM, Toledo I, Balestracci A.
-
Biomedicines. 2025 Jun 13;13(6):1460. doi: 10.3390/biomedicines13061460.
2025/06/26
Reshaping Dyslipidaemia Treatment with Bempedoic Acid-A Narrative Review
Strikic D, Begic Z, Radman I, Zlopasa F, Mateljic J, Zec I, Titlic M, Sliskovic AM, Pecin I, Reiner Z, Mercep I.
-
Biomedicines. 2025 Jun 9;13(6):1411. doi: 10.3390/biomedicines13061411.
2025/06/26
Pharmacokinetics and Ex Vivo Activity of 7-Methylxanthine, an Inhibitor of Monosodium Urate Crystallization
Ferrer MD, Dietrich J, Isern B, Pérez-Ferrer MDM, Albertí J, Grases F, Costa-Bauzà A.
-
Ter Arkh. 2025 Jun 8;97(5):455-462. doi: 10.26442/00403660.2025.05.203227.
2025/06/25
[Features of diet in patients with cardiometabolic diseases with gout and hyperuricemia: A review]
Gromova MA, Tsurko VV, Starodubova AV, Kislyak OA.
-
J Cardiovasc Dev Dis. 2025 May 28;12(6):202. doi: 10.3390/jcdd12060202.
2025/06/25
The Role of Serum Uric Acid and Serum Creatinine Ratio as Possible Markers of Autonomic Dysfunction and Left Ventricular Mass Index in Atherosclerotic Renal Artery Stenosis
Gigante A, Cascone R, Pellicano C, Iannazzo F, Gadaleta FR, Rosato E, Cianci R.
-
Clin Pract. 2025 Jun 19;15(6):114. doi: 10.3390/clinpract15060114.
2025/06/25
Bone Marrow Aplasia and Neutropenic Fever Following Azathioprine Dose Escalation in a TPMT-Deficient Patient with Crohn's Disease and Psoriatic Arthritis-A CARE-Compliant Case
Wroński K, Holecki MT, Boguszewska N, Skrzypczak-Zielińska M, Chudek JT.
-
Diabetes Obes Metab. 2025 Jun 25. doi: 10.1111/dom.16532. Online ahead of print.
2025/06/25
Efficacy and safety of PEGylated uricase in healthy adults and patients with hyperuricaemia: A phase I, randomized, double-blind, dose-escalation, placebo-controlled trial
Sun F, Zhang J, Yan Z, Yu Q, Wang P, He Y, Liu M, Huang B, Fang L, Xu Y, Fu Y, Gao X, Li C, Cao Y.
-
Biochem Res Int. 2025 Jun 17;2025:1691257. doi: 10.1155/bri/1691257. eCollection 2025.
2025/06/25
Density Functional Theory, Molecular Docking Study, and In Vitro Antioxidant Activity of Cinnamic Acid Isolated From Piper betle Leaves
Tumilaar SG, Hardianto A, Dohi H, Kurnia D.
-
Eur Cardiol. 2025 Jun 12;20:e18. doi: 10.15420/ecr.2024.30. eCollection 2025.
2025/06/25
New Insights into Uric Acid Metabolism in the Pathophysiology of Ischaemic Heart Disease
Piani F, Annesi L, Borghi C.
-
Ren Fail. 2025 Dec;47(1):2515527. doi: 10.1080/0886022X.2025.2515527. Epub 2025 Jun 24.
2025/06/25
Application of serum STIM1, AOPPS, and urinary NGAL, AGT in the diagnosis of hypertensive nephropathy
Li B, Wang C, Ouyang D, Xu H, Wu Z, Yang X.
-
PLoS One. 2025 Jun 24;20(6):e0325775. doi: 10.1371/journal.pone.0325775. eCollection 2025.
2025/06/24
Hyperuricemia and associated factors among adult cardiovascular disease patients at Salale University Comprehensive Specialized Hospital, Fitche, Central Ethiopia
Rufe NB, Lamesa TA, Mamo AG, Zewude BM, Addisu B, Nigusie DJ, Biya SA.
-
PLoS One. 2025 Jun 24;20(6):e0326317. doi: 10.1371/journal.pone.0326317. eCollection 2025.
2025/06/24
Hederagenin's uric acid-lowering effects in hyperuricemic mice: Mechanistic insights from molecular docking and in vivo analysis
Chen P, Tian YN, Wang JT, Yin XL, Guan BS, Bai X.
-
Int J Biol Macromol. 2025 Jun 17:145344. doi: 10.1016/j.ijbiomac.2025.145344. Online ahead of print.
2025/06/24
Reduction mechanism of XOR-mediated nitroaromatics hypoxia targeted AGT inhibitors: Molecular docking, MD simulation and ONIOM (QM/MM) investigation
Wang J, Ren T, Sun G, Zhang N, Zhao L, Zhong R.
-
J Agric Food Chem. 2025 Jun 24. doi: 10.1021/acs.jafc.5c01770. Online ahead of print.
2025/06/24
Screening and Identification of Multitarget Uric Acid-Lowering Peptides Derived from Rice Residue Protein and Analysis of Their Mechanisms
Bi X, Huang R, Qu T, Wu Y, Wu H, Mu D, Hu J, Liao J, Duan Y, Wen L.
-
J Clin Hypertens (Greenwich). 2025 Jun;27(6):e70076. doi: 10.1111/jch.70076.
2025/06/24
Effects of Allisartan on Uric Acid, Left Atrial, Left Ventricular, and Artery Stiffness in Mild-to-Moderate Essential Hypertension
Sun Y, Wu H, Zhang Y, Liu Y, Gong M, Song W, Jiang Y.
-
Mol Biomed. 2025 Jun 23;6(1):43. doi: 10.1186/s43556-025-00287-2.
2025/06/24
Fructose metabolism and its roles in metabolic diseases, inflammatory diseases, and cancer
Li Z, Fan X, Gao F, Pan S, Ma X, Cheng H, Nakatsukasa H, Zhang W, Zhang D.
-
Front Public Health. 2025 Jun 6;13:1557721. doi: 10.3389/fpubh.2025.1557721. eCollection 2025.
2025/06/24
An unsupervised cluster analysis of multimorbidity patterns in older adults in Shenzhen, China
Guo X, Liu P, Guo J, Zhang N, Huang H, Liu J, Tan Z, Dan G.
-
SAGE Open Med Case Rep. 2025 Jun 20;13:2050313X251351769. doi: 10.1177/2050313X251351769. eCollection 2025.
2025/06/24
Misdiagnosis of sacroiliac joint gout as ankylosing spondylitis: Solving the diagnostic dilemma with dual-energy computed tomography
Tu JJ, Wang JX, Xu SQ.
-
Ther Adv Infect Dis. 2025 Jun 20;12:20499361251347698. doi: 10.1177/20499361251347698. eCollection 2025 Jan-Dec.
2025/06/24
Prevalence and factors associated with hyperuricemia among people living with HIV in Uganda: a cross-sectional study at a tertiary hospital in Uganda
Mutinye Kwesiga J, Nkonge R, Namanda B, Nabwana M, Baluku JB.
-
Int J Biol Macromol. 2025 Jun 20:145336. doi: 10.1016/j.ijbiomac.2025.145336. Online ahead of print.
2025/06/23
The anti-hyperuricemia effects of polysaccharide from Saccharina japonica through gut-kidney axis
Yu H, Dong K, Fu M, Wang H, Wang J, Zhang Q, Yue Y, Geng L, Wu N.
-
J Ethnopharmacol. 2025 Jun 20;352:120185. doi: 10.1016/j.jep.2025.120185. Online ahead of print.
2025/06/23
Antihyperuricemic, hepatoprotective and nephroprotective roles of Benincasae Exocarpium in hyperuricemia rats
Tong R, Ding B, Chen S, Yang W, Yi Y, He W, Zhou R, Wang Y, Li W, Qin S.
-
Food Chem. 2025 Jun 14;491:145112. doi: 10.1016/j.foodchem.2025.145112. Online ahead of print.
2025/06/23
An intelligent colorimetric paper-based hypoxanthine biosensor enabled by smartphone and dual-enzyme system for efficient shrimp freshness monitoring
Dong W, Feng R, Pang J, Wei K, Li J, Sun J, Wang S, Mao X.
-
Free Radic Biol Med. 2025 Jun 19;238:169-178. doi: 10.1016/j.freeradbiomed.2025.06.034. Online ahead of print.
2025/06/22
Hinokitiol modulates Nrf2/HO-1 signaling, autophagy, and URAT1 in hyperuricemia and oxidative stress models of renal injury
Chiang YF, Huang KC, Huang YJ, Wang KL, Huang YJ, Shieh TM, Ali M, Hsia SM.
-
Med Sci Monit. 2025 Jun 21;31:e948665. doi: 10.12659/MSM.948665.
2025/06/21
Comparative Analysis of Oxidative Stress Biomarkers in 50 Primary Open-Angle Glaucoma Patients
Seven E, Tekin S.
-
Phytomedicine. 2025 Jun 11;145:156974. doi: 10.1016/j.phymed.2025.156974. Online ahead of print.
2025/06/21
Moslae Herba extract alleviates hyperuricemia by regulating uric acid metabolism and relieving renal inflammation and fibrosis in mice
Guo J, Liu H, Jin T, Jia J, Zhu W, Xia X.
-
Comput Biol Chem. 2025 Jun 13;119:108557. doi: 10.1016/j.compbiolchem.2025.108557. Online ahead of print.
2025/06/21
Computer-aided screening of phytoconstituents from Plumeria species targeting xanthine oxidase inhibition: a combination of pharmacokinetics, molecular docking and molecular dynamics approaches
Sahoo GG, Nayak A, Gadnayak A, Dash B, Jena S, Ray A, Panda PC, Nayak S, Sahoo A.
-
J Evid Based Med. 2025 Jun;18(2):e70049. doi: 10.1111/jebm.70049.
2025/06/20
Sex Differences in the Effects of Cadmium and Uric Acid Levels on Hypertension Risk: A Dose-Response Relationship and Synergistic Effect Study
Yang R, Chen Y, Hui X, Fan X, Li X, Kong W, Liu Q, Chen Y, Wang K, Li X, Yan P, Tian J, Lu Y.
-
ACS Pharmacol Transl Sci. 2025 May 15;8(6):1778-1790. doi: 10.1021/acsptsci.5c00209. eCollection 2025 Jun 13.
2025/06/19
Structural Insights into the Substrate Egress Pathways Explains Specificity and Inhibition of Human Glucose Transporters (GLUT1 and GLUT9)
Xu M, Jiang J, Gao L, Alyemni SO, Haider S.
-
BMJ Open. 2025 Jun 18;15(6):e094421. doi: 10.1136/bmjopen-2024-094421.
2025/06/19
Validation of salivary uric acid remote self-monitoring for early prediction of hypertensive disorders of pregnancy: study protocol for a prospective, observational, multicentre cohort study
Chmielewska B, Reading I, Bhide A, Ganapathy R, Thilaganathan B.
-
S D Med. 2025 Apr;78(4):177-181.
2025/06/19
Pseudogout in Primary Care Practice: An Approach to Diagnosis and Treatment
Sekeramayi TM, Sivaprakasam T, Fanciullo J.
-
Bioelectrochemistry. 2025 Jun 16;166:109032. doi: 10.1016/j.bioelechem.2025.109032. Online ahead of print.
2025/06/19
Self-assembled enzyme biosensors based on xanthine oxidase (XO) and CS@GO for screening natural products for anti-gout active ingredients
Gao T, Sun B, Wang B, Da X, Lv Y, Zhou M, Wang X, Wu Y, Li H, He H, Kang J, Wang X, Qin C, Yang L.
-
Rev Assoc Med Bras (1992). 2025 Jun 16;71(5):e20241889. doi: 10.1590/1806-9282.20241889. eCollection 2025.
2025/06/18
Role of Netrin-1 in staging hypoxic ischemic encephalopathy
Aycan N, Demir DÇ, Yürektürk E, Başaranoglu M, Karaman S, Tuncer O.
-
J Diabetes Investig. 2025 Jun 18. doi: 10.1111/jdi.70106. Online ahead of print.
2025/06/18
Relationship of the intensity of physical performance and sedentary time with uric acid in patients with type 2 diabetes
Li J, Zhang E, Dong Z, Liu Y.
-
Food Funct. 2025 Jun 18. doi: 10.1039/d5fo00580a. Online ahead of print.
2025/06/18
2'-Fucosyllactose evokes colonization of Alloprevotella and alleviates renal injury in hyperuricemia mice
Lei Y, Sun S, Chen L, Wang Y.
-
ACS Med Chem Lett. 2025 May 8;16(6):1163-1169. doi: 10.1021/acsmedchemlett.5c00204. eCollection 2025 Jun 12.
2025/06/18
Discovery and Optimization of 6‑Azaindole URAT1 Inhibitors to Address Kidney and Liver Related Toxicities
Jin Q, Wu TY.
-
Arthritis Care Res (Hoboken). 2025 Jun 18. doi: 10.1002/acr.25584. Online ahead of print.
2025/06/18
Time trends and predictors of gout remission over six years
Tabi-Amponsah AD, Stewart S, Gamble G, Stamp LK, Taylor WJ, Dalbeth N.
-
Kidney Res Clin Pract. 2025 Jun 18. doi: 10.23876/j.krcp.24.321. Online ahead of print.
2025/06/18
Role of urate transporters in the kidneys and intestine in uric acid homeostasis
Kim SH, Shin J, Son HE, Kang DH.
-
Cardiovasc Toxicol. 2025 Jun 17. doi: 10.1007/s12012-025-10022-6. Online ahead of print.
2025/06/18
Maternal Electronic Cigarette Inhalation Exposure During Gestation: Impacts on Prolactin and Xanthine Oxidase
Griffith JA, Schafner KJ, Garner KL, DeVallance E, Lewis SE, Nurkiewicz TR, Kelley EE, Maxwell BA, Goldsmith WT, Bowdridge EC.
-
Free Radic Biol Med. 2025 Jun 14:S0891-5849(25)00768-3. doi: 10.1016/j.freeradbiomed.2025.06.019. Online ahead of print.
2025/06/17
Xanthine Oxidoreductase Expression is Diminished in Breast Cancer as a Response to Uric Acid Mediated Chelation of Redox Active Iron
Chapa MG, King RD, Dean ZW, Maskey A, Park RM, Velayutham M, Pugacheva EN, Woodward OM, Webb BA, Spitz DR, Kelley EE.