本コンテンツは、医療従事者にとって有用な学術情報をお届けすることを目的としており、
公平な立場から一定のキーワードを元に選択した高尿酸血症や痛風に関する記事をお届けしています。
一部、国内での承認外の情報が含まれることもありますが、これを推奨するものではありません。
また、特定の薬剤の処方誘引あるいは企業の営利を企図するものではありません。
治療、各薬剤の使用にあたっては最新の製品添付文書をご参照ください。
論文タイトルを押すとPubmedもしくは医中誌Webへ移動します。
※なお、医中誌Web利用には会員登録が必要になります。
新着論文
-
福岡県立大学人間社会学部紀要(1349-0230)33巻1号 Page95-105(2024.10)
2025/07/01
医中誌文献番号:Z526020003
国保データベース(KDB)システムを活用した疾病別医療費の地域差分析 2022(令和4)年度の福岡県市区町村を対象として石崎 龍二(福岡県立大学 人間社会学部)
-
日本循環器学会学術集会抄録集89回 Page PJ19-5(2025.03)
2025/07/01
医中誌文献番号:Z410601533
The Effect of a Selective Urate Reabsorption Inhibitor Dotinurad on Uric Acid and Renal Function with Hyperuricemia(タイトル和訳中)(英語)溝口 達也(名古屋市立大学/大学院医学研究科循環器内科学), 新谷 康広, 河田 侑, 横井 雅史, 山邊 小百合, 森 賢人, 菊池 祥平, 伊藤 剛, 北田 修一, 後藤 利彦, 瀬尾 由広
-
日本循環器学会学術集会抄録集89回 Page PL05-5(2025.03)
2025/07/01
医中誌文献番号:Z410600042
Effects of Xanthine Oxidase Inhibitors(XOI) on ATP Storage and XOI Withdrawal Syndrome(タイトル和訳中)(英語)Kuwabara Masanari(Division of Public Health and Division of Cardiology, Jichi Medical University)
-
川崎市立川崎病院事例研究集録(2434-8058)26回 Page161-164(2024.03)
2025/07/01
医中誌文献番号:2025221395
離床に拒否があった患者の排泄動作への看護吉開 愛海(川崎市立川崎病院 看護部12階南病棟)
-
皮膚病診療(0387-7531)47巻5号 Page385-391(2025.05)
2025/07/01
医中誌文献番号:2025221066
【アトピー性皮膚炎と誤診される皮膚疾患】多形慢性痒疹患者の併存疾患についての検討山本 哲久(宝塚市立病院 皮膚科), 中内 恵美, 大塚 晴彦, 笹瀬 玲奈, 山本 萌絵, 一ノ瀬 里紗
-
Drug Chem Toxicol. 2025 Jul 11:1-12. doi: 10.1080/01480545.2025.2529514. Online ahead of print.
2025/07/11
Effects of tris(2-chloroethyl)phosphate on hyperuricemia revealed by network toxicology and in vitro experimental validation
Huang Y, Jiang C, Li F, Ma X.
-
J Clin Med Res. 2025 Jun 9;17(6):320-333. doi: 10.14740/jocmr6250. eCollection 2025 Jun.
2025/07/11
The Long-Term Effects of the Selective Inhibitor of Urate Transporter 1, Dotinurad, on Metabolic Parameters and Renal Function in Japanese Patients With Asymptomatic Hyperuricemia
Yanai H, Adachi H, Hakoshima M, Katsuyama H.
-
Biochem Biophys Rep. 2025 Jun 23;43:102103. doi: 10.1016/j.bbrep.2025.102103. eCollection 2025 Sep.
2025/07/11
Prophylactic role of omega 3 fatty acids in bisphenol F-induced sexual and erectile dysfunction is associated with penile redox homeostasis
Odetayo AF, Hamed MA, Bassey GE, Titiloye OO, Maduabuchi SD, Okesina KB, Olayaki LA.
-
Food Chem. 2025 Jul 5;492(Pt 2):145447. doi: 10.1016/j.foodchem.2025.145447. Online ahead of print.
2025/07/11
Characterizing metabolites and biotransformation in lactic acid bacteria fermented Millennium cherry tomato juice using integrated analytical tools
Wang H, Sakda P, Chen L, Xie J, Yu J, Liu B, Vongsangnak W, Wang R.
-
Heart Lung. 2025 Jul 9;74:121-128. doi: 10.1016/j.hrtlng.2025.07.001. Online ahead of print.
2025/07/11
Inflammation markers associated with symptoms and neighborhood deprivation in black adults with heart failure
Butts B, Herring C, Madariaga A, Graven LJ, Higgins MK, Dunbar SB.
-
Bioorg Chem. 2025 Jul 5;163:108727. doi: 10.1016/j.bioorg.2025.108727. Online ahead of print.
2025/07/11
A new utilization of saponins from the root of Clematis chinensis Osbeck: Hypouricemia effect
Liu S, Dong H, Geng W, Liu Y, Arachchige BNP, Wang X.
-
Adv Pharm Bull. 2025 Apr 4;15(1):11-26. doi: 10.34172/apb.44012. eCollection 2025 Apr.
2025/07/10
Gouty Arthritis Treatment: Advancements in Topical Lipid-Based Nanocarrier Delivery Systems
Kumar S, Kaul S, Jain N, Jain C, Pandey M.
-
Front Pharmacol. 2025 Jun 25;16:1565530. doi: 10.3389/fphar.2025.1565530. eCollection 2025.
2025/07/10
Efficacy of different dosages of common uric acid-lowering medications in gout patients: a network meta-analysis of randomized control trials
Zheng X, Xie C, Fang J, Huang Z, Huang J, Zhao L, Ye G, Wang H.
-
Biomed Eng Online. 2025 Jul 9;24(1):86. doi: 10.1186/s12938-025-01418-0.
2025/07/10
Clinical value of serum uric acid and homocysteine levels in predicting the occurrence of atrial fibrillation in patients with type 2 diabetes mellitus
Li D, Deng J, Ma L.
-
Eur J Intern Med. 2025 Jul 8:S0953-6205(25)00271-7. doi: 10.1016/j.ejim.2025.06.033. Online ahead of print.
2025/07/10
Prognostic impact of uric acid levels in heart failure with mildly reduced ejection fraction: Insights from a large retrospective registry
Schmitt A, Behnes M, Bertsch T, Reinhardt M, Goertz M, Abel N, Lau F, Weidner K, Dudda J, Steffen HJ, Abumayyaleh M, Duerschmied D, Akin I, Schupp T.
-
Chem Res Toxicol. 2025 Jul 21;38(7):1227-1238. doi: 10.1021/acs.chemrestox.5c00101. Epub 2025 Jul 9.
2025/07/10
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1,8-Dinitropyrene and Its Metabolite 1-Amino-8-nitropyrene via Nitroreduction in Human Lung Cells
Su AL, Marques CF, Krzeminski J, El-Bayoumy K, Penning TM.
-
PLoS One. 2025 Jul 9;20(7):e0327864. doi: 10.1371/journal.pone.0327864. eCollection 2025.
2025/07/09
Quzhuo tongbi formula for reducing gout flare related to uric acid lowering treatment: Study protocol for a multiple-center, randomized, double-blind, placebo, parallel-controlled clinical trial
Pan H, Li X, Wu S, Zhou D, Guan H, Wu H, Wang Q, Tang Y, Hu X, Wang M, Zhou M, Huang R, Liu L, Chen Y, Wen C, Huang L.
-
Eur J Heart Fail. 2025 Jul 9. doi: 10.1002/ejhf.3723. Online ahead of print.
2025/07/09
Effects of empagliflozin on uric acid levels during acute heart failure recompensation: A sub-analysis of the EMPAG-HF trial (Effects of Empagliflozin on Diuresis and Renal Function in Patients with Acute Decompensated Heart Failure)
Bogoviku J, Nguyen TD, Westphal JG, Haertel F, Aftanski P, Möbius-Winkler S, Busch M, Schulze PC.
-
Kidney Int Rep. 2025 Apr 29;10(6):1630-1632. doi: 10.1016/j.ekir.2025.04.049. eCollection 2025 Jun.
2025/07/09
The Promise of Dotinurad for Hyperuricemia in CKD
Li AS, Garimella PS.
-
Kidney Int Rep. 2025 Apr 3;10(6):1711-1720. doi: 10.1016/j.ekir.2025.03.047. eCollection 2025 Jun.
2025/07/09
Dotinurad Treatment for Patients With Hyperuricemia Complicating CKD
Tanabe K, Nunoue T, Itabashi N, Katayama A, Nakamura A, Ohbayashi H, Onishi Y, Watanabe K, Maruyama K, Hosoya T, Okada S, Wada J; DTN-CKD Investigators.
-
Medicine (Baltimore). 2025 Jul 4;104(27):e43179. doi: 10.1097/MD.0000000000043179.
2025/07/09
Knowledge and practice of gout treatment recommendations by primary health care physicians in Saudi Arabia: A cross-sectional study across five different regions
Alharbi S, Alharthi N, Almuteri D, Jan R, Alsaedi S, Alwakeel A, Alhumaidi N.
-
Food Funct. 2025 Jul 28;16(15):6080-6100. doi: 10.1039/d5fo00951k.
2025/07/08
Weizmannia coagulans BC99 alleviates hyperuricemia by restoring liver-kidney-gut axis dysfunction caused by hyperuricemia
Wu Y, Gao Y, Li C, Zhai S, Dong Y, Tie S, Zhao L, Gu S.
-
Cell Biochem Funct. 2025 Jul;43(7):e70100. doi: 10.1002/cbf.70100.
2025/07/08
Smilax glabra Roxb. Meliorates Hyperuricemia via Regulating Renal Urate Transporter and Remodelulating Intestinal Microbiota in Mice
Xiao J, He W, Fang X, Zhou R, Huang A, Wang Y, Du Q, Xu L, Cheng F, Zeng H.
-
Zhonghua Yi Xue Za Zhi. 2025 Jul 8;105:2469-2482. doi: 10.3760/cma.j.cn112137-20250126-00222. Online ahead of print.
2025/07/08
[Expert consensus on urate-lowering therapy for high-risk hyperuricemia (2025 edition)]
Chinese Rheumatology Association; Committee for Rheumatologists and Immunologists of Chinese Primary Health Care Foundation.
-
J Nutr Biochem. 2025 Jul 5;145:110021. doi: 10.1016/j.jnutbio.2025.110021. Online ahead of print.
2025/07/08
Baseline 25-hydroxyvitamin D as a stronger protector against type 2 diabetes in the context of hyperuricemia and gout: a cohort study based on the UK biobank
Han Y, Wu J, Yao M, Xie T, Li Z, Zhao H, Zhang Y, Zeng X.
-
PeerJ. 2025 Jul 3;13:e19618. doi: 10.7717/peerj.19618. eCollection 2025.
2025/07/07
Serum miR-15a-5p may predict recurrence of atrial fibrillation after catheter ablation: a single center retrospective study
Ruan ZB, Peng Q, Sun XJ, Wang F, Zhu L.
-
J Cardiovasc Nurs. 2025 Jul 7. doi: 10.1097/JCN.0000000000001234. Online ahead of print.
2025/07/07
Impact of Nurse-Led Cardiovascular Risk Assessment and Management Program on 1-Year Outcomes in Patients on Hemodialysis Post Percutaneous Coronary Intervention
Zhao W, Zhao W, Sun X.
-
J Cardiothorac Surg. 2025 Jul 5;20(1):285. doi: 10.1186/s13019-025-03448-0.
2025/07/06
A two-sample Mendelian randomization study of atrial fibrillation screening, risk factor analysis, and serum uric acid levels
Shi Z, Hu W, Ye K, Xia R.
-
Cancer Lett. 2025 Jul 3;630:217888. doi: 10.1016/j.canlet.2025.217888. Online ahead of print.
2025/07/06
Endoplasmic reticulum stress-driven nucleotide catabolism fuels prostate cancer
Deng K, Pällmann N, Livgård M, Kildal W, Pradhan M, Fazli L, Rennie PS, Jin Y, Saatcioglu F, Kuzu OF.
-
J Physiol Sci. 2025 Jul;75(2):100029. doi: 10.1016/j.jphyss.2025.100029. Epub 2025 Jun 29.
2025/07/06
Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice
Mitsubayashi T, Suita K, Ohnuki Y, Ishikawa M, Ito A, Matsuo I, Miyamoto G, Abe M, Morii A, Mototani Y, Nariyama M, Matsubara R, Hayakawa Y, Okumura S.
-
BMJ Open. 2025 Jul 3;15(7):e099442. doi: 10.1136/bmjopen-2025-099442.
2025/07/05
Effects of febuxostat on heart failure patients with asymptomatic hyperuricaemia: a retrospective cohort study
Long X, Wang Z, Yuan W.
-
J Sep Sci. 2025 Jul;48(7):e70209. doi: 10.1002/jssc.70209.
2025/07/04
Screening and Identification of Anti-Gout Components From Herb Pair Combining Ultrafiltration-HPLC-MS, On-Line HPLC-2,2'-Azinobis(3-Ethylbenzothiazoline-6-Sulfonic Acid)-MS and In Silico Analysis: Case Study by Smilacis Glabrae Rhizoma-Dioscoreae Spongiosae Rhizoma
Hu S, Guo H, Miao R, Yu J, Wang X, Zhao H.
-
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2025 Jun;33(3):822-827. doi: 10.19746/j.cnki.issn.1009-2137.2025.03.029.
2025/07/04
[Correlation between Serum FGF-23, HPSE Levels and Early Renal Impairment in Patients with Multiple Myeloma]
Ma LF, Yun Y, Liu YQ, Bai XQ, Ni WJ, Li ZQ, Lu Y, Li Z, Li J, Jia GR.
-
Cureus. 2025 Jul 2;17(7):e87183. doi: 10.7759/cureus.87183. eCollection 2025 Jul.
2025/07/04
Outcomes in Patients With Multiple Myeloma and Prescribed Urate-Lowering Therapy: A Propensity-Matched Study
Eidbo S, Barnett M, Lema Rodriguez D, Tsibadze N, Pappas A, Shah M, Shah A, Mayo R.
-
Kidney Med. 2025 May 8;7(7):101021. doi: 10.1016/j.xkme.2025.101021. eCollection 2025 Jul.
2025/07/04
Effectiveness of Allopurinol on Uric Acid and Pediatric Chronic Kidney Disease Severity in the Chronic Kidney Disease in Children Study
Ng DK, Matheson MB, Schwartz GJ, Kurgansky KE, Warady BA, Furth SL.
-
Clin Case Rep. 2025 Jul 2;13(7):e70573. doi: 10.1002/ccr3.70573. eCollection 2025 Jul.
2025/07/04
A Rare Case Report of an Adult With Intraspinal Gouty Stones and Concurrent Knee Joint Involvement
Cao B, Wang J.
-
J Inherit Metab Dis. 2025 Jul;48(4):e70054. doi: 10.1002/jimd.70054.
2025/07/04
Correlation of Plasma and Urine 2,8-Dihydroxyadenine and Adenine and Clinical Characteristics in Individuals With Adenine Phosphoribosyltransferase Deficiency
Thorsteinsdottir UA, Runolfsdottir HL, Edvardsson VO, Thorsteinsdottir M, Palsson R.
-
BMC Public Health. 2025 Jul 3;25(1):2297. doi: 10.1186/s12889-025-23483-9.
2025/07/04
Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015-2018
Mao D, Mu J, Li Y, He L, Chai Q, Zhao X, Ren X, Cheng H.
-
Res Social Adm Pharm. 2025 Jun 27:S1551-7411(25)00375-4. doi: 10.1016/j.sapharm.2025.06.108. Online ahead of print.
2025/07/04
Effectiveness of pharmacist-led interventions in improving gout outcomes: A systematic review
Tanveer M, Tahir AH, Shrestha S, Raza MZ, Ahmed A.
-
Emerg Med Clin North Am. 2025 Aug;43(3):453-461. doi: 10.1016/j.emc.2025.04.002. Epub 2025 May 12.
2025/07/04
Tumor Lysis Syndrome
Lindsay AB, Levy NJ, McAndrew ML.
-
Am J Kidney Dis. 2025 Jul 1:S0272-6386(25)00924-2. doi: 10.1053/j.ajkd.2025.04.020. Online ahead of print.
2025/07/04
Gout Management in Patients With CKD
Ostrowski RA.
-
Redox Biol. 2025 Jun 30;85:103748. doi: 10.1016/j.redox.2025.103748. Online ahead of print.
2025/07/04
A critical role for gastric xanthine oxidoreductase in the formation of S-nitrosothiols and blood pressure responses to nitrite in rats
de Azevedo Medeiros CF, Neto-Neves EM, Santana IV, Sanches-Lopes JM, Nogueira RC, Batista RIM, Conde-Tella SO, Montenegro MF, Tanus-Santos JE.
-
PLOS Glob Public Health. 2025 Jul 3;5(7):e0003946. doi: 10.1371/journal.pgph.0003946. eCollection 2025.
2025/07/03
Tobacco smoking and biomarker profile among beverage industrial workers and their spouses in Rwanda: A cross-sectional study
Nsanzabera C, Rukundo JC, Said MY, Ndayisenga L.
-
Curr Res Microb Sci. 2025 Jun 12;9:100422. doi: 10.1016/j.crmicr.2025.100422. eCollection 2025.
2025/07/03
Comparative analysis of hyperuricemia induction methods and probiotic interventions in mice
Wang Y, Zhang H, Liu S, Sun S, Ren W, Wang T, Zhang S, Yao H, Jin C, Wu N.
-
Eur J Med Res. 2025 Jul 2;30(1):554. doi: 10.1186/s40001-025-02845-4.
2025/07/03
Association of serum uric acid-to-high-density lipoprotein cholesterol ratio (UHR) with risk of myocardial infarction among individuals with diabetes: a cross-sectional analysis using data from NHANES 2005-2020
Sun S, Xu H, Liu L, Luan Z, Liu C, Zhi F.
-
Am J Physiol Cell Physiol. 2025 Aug 1;329(2):C500-C512. doi: 10.1152/ajpcell.00673.2024. Epub 2025 Jul 2.
2025/07/03
Pentagalloyl glucose inhibits monosodium urate-induced inflammation and NLRP3 inflammasome formation via TAK1
Panipinto PM, Yue GE, Prasad B, Ahmed S.
-
Med Pr. 2025 Jun 30:205890. doi: 10.13075/mp.5893.01624. Online ahead of print.
2025/07/02
[Postoperative delirium in the elderly]
Wróbel M, Wołkowiecki M, Janocha A, Jabłońska Z.
-
Clin Kidney J. 2024 Dec 9;18(4):sfae400. doi: 10.1093/ckj/sfae400. eCollection 2025 Apr.
2025/07/02
Allopurinol use predicts lower low-density lipoprotein cholesterol in patients with pre-dialysis chronic kidney disease-a prospective cohort study
Taskapan H, Ma H, Taskapan B, Tam P, Sikaneta T.
-
Minerva Med. 2025 Jul 2. doi: 10.23736/S0026-4806.25.09712-5. Online ahead of print.
2025/07/02
An overview of the role of serum uric acid to high-density lipoprotein cholesterol ratio in type 2 diabetes mellitus and in other inflammatory and metabolic conditions
Aktas G.
-
BMC Med Inform Decis Mak. 2025 Jul 1;25(1):229. doi: 10.1186/s12911-025-03025-4.
2025/07/02
Mortality predicting models for patients with infective endocarditis: a machine learning approach
Zi-Yang Y, Qi W, Liu X, Li H, Wang S, Yu D, Wei X.
-
BMC Psychiatry. 2025 Jul 1;25(1):668. doi: 10.1186/s12888-025-06885-2.
2025/07/02
Establishment and validation of a model for predicting depression risk in stroke patients
Lin F, Zhou M.
-
Food Res Int. 2025 Oct;217:116770. doi: 10.1016/j.foodres.2025.116770. Epub 2025 Jun 9.
2025/07/02
Secoisolariciresinol diglucoside (SDG) from flaxseed meal alleviates hyperuricemia in mice by regulating uric acid metabolism and intestinal homeostasis
Wang S, Chen J, Li Y, Wang Y.
-
Sci Rep. 2025 Jul 1;15(1):20728. doi: 10.1038/s41598-025-07665-4.
2025/07/02
Elevated serum CA72-4 as a novel diagnostic biomarker for acute gout flares
Zhuang Y, Hu X, Cai Q, Huang H, Yang X.
-
Sci Rep. 2025 Jul 2;15(1):22856. doi: 10.1038/s41598-025-06114-6.
2025/07/02
Assessment of drug induced hyperuricemia and gout risk using the FDA adverse event reporting system
Zheng G, Lu M, Ouyang Y, Chen S, Hu B, Xu S, Sun G.
-
Sci Rep. 2025 Jul 2;15(1):22797. doi: 10.1038/s41598-025-04670-5.
2025/07/02
Multi-omics analysis of diabetic cardiomyopathy pathogenesis using a type 2 diabetic Zucker diabetic fatty rat model
Tanabe K, Zheng Q, Zhang X, Tanaka N, Hayashi C, Yokota A, Otsuka R, Katahira T, Kohjima M, Nakamuta M.
-
Sci Rep. 2025 Jul 1;15(1):21051. doi: 10.1038/s41598-025-07212-1.
2025/07/02
The predictive value of triglyceride glucose-body mass index for contrast-induced nephropathy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
Liu L, Yuan Z, Ning X, Wang J, Li Y, Song X, Zhang F.
-
Sci Rep. 2025 Jul 1;15(1):21079. doi: 10.1038/s41598-025-06842-9.
2025/07/02
Alteration in epigenetic profile in subclinical atherosclerosis and in high uric acid
Beik-Khormizi M, Zare-Khormizi MR, Firoozabadi AD, Vakili M, Hekmatimoghaddam S, Pourrajab F.
-
PLoS One. 2025 Jul 1;20(7):e0326858. doi: 10.1371/journal.pone.0326858. eCollection 2025.
2025/07/01
Ficus benghalensis extract mediated green synthesis of silver nanoparticles, its optimization, characterization, computational studies, and its in vitro and in vivo biological potential
Din IU, Ajaj R, Rauf A, Ahmad Z, Muhammad N, Ali S, Hemeg HA, Ullah I.
-
J Clin Hypertens (Greenwich). 2025 Jul;27(7):e70094. doi: 10.1111/jch.70094.
2025/07/01
Development and Validation of a Nomogram for Predicting the Probability of Postpartum Chronic Hypertension in Women With Hypertensive Disorders of Pregnancy: A Multicenter, Cross-Sectional Study
Liu Q, Gong M, Su Z, Xu H, Zhao Z, Zhang Y, Jiang Y, Song W.
-
Medicine (Baltimore). 2025 Jun 27;104(26):e43104. doi: 10.1097/MD.0000000000043104.
2025/07/01
Risk factors for developing hypertension in patients with type 2 diabetes: A cross-sectional study
Liu L, Mu J, Wang X, Gu Y, Zhou S, Ma X, Xu J, Liu Y, Ren X, Duan Z, Yuan L, Wang Y.
-
Metabol Open. 2025 Jun 13;27:100374. doi: 10.1016/j.metop.2025.100374. eCollection 2025 Sep.
2025/07/01
Association of hepatic steatosis with increased plasma xanthine oxidoreductase activity: MedCity21 health examination registry
Kurajoh M, Fukumoto S, Akari S, Nakamura T, Miki Y, Nagata Y, Morioka T, Mori K, Imanishi Y, Watanabe T, Emoto M.
-
Biotech Histochem. 2025 Jun 30:1-21. doi: 10.1080/10520295.2025.2518213. Online ahead of print.
2025/07/01
Apocynin may alleviate side effects of autophagy-blocked radiotherapy through antioxidant effects
Sezen Us A, Dagsuyu E, Us H, Cöremen M, Karabulut Bulan O, Yanardag R.
-
Arthritis Care Res (Hoboken). 2025 Jun 30. doi: 10.1002/acr.25590. Online ahead of print.
2025/07/01
Reply to "Febuxostat use is associated with a significantly greater risk of mild to moderate perturbation of liver function compared to benzbromarone in patients with gout: comment on the article by Sun et al"
Sun W, Cui L, Li C.
-
Arthritis Care Res (Hoboken). 2025 Jun 30. doi: 10.1002/acr.25591. Online ahead of print.
2025/07/01
Febuxostat use is associated with a significantly greater risk of mild to moderate perturbation of liver function compared to benzbromarone in patients with gout: comment on the article by Sun et al
Wang G, Liu Z.
-
J Clin Hypertens (Greenwich). 2025 Jun;27(6):e70081. doi: 10.1111/jch.70081.
2025/07/01
Associations of Blood Pressure Variability, Heart Rate, and Target Organ Damage in Resistant Hypertension Patients
He X, Chen X, Chen L, Huang L, Luo X, Tan H.
-
Precision Medicine(2434-3625)8巻6号 Page473-475(2025.06)
2025/07/01
医中誌文献番号:Z520120009
研究者の最新動向 労働者におけるNormal-Weight Central Obesityと疾病リスクに関する大規模データ研究白澤 貴子(昭和医科大学 医学部衛生学公衆衛生学講座), 落合 裕隆, 吉本 隆彦, 長濱 さつ絵
-
透析ケア(1341-1489)2025夏季増刊 Page273-274(2025.06)
2025/07/16
医中誌文献番号:2025224062
【作用機序から患者指導までまるっとわかる 透析室の薬剤カタログ462】(第4章)透析患者に禁忌の薬 糖尿病・内分泌代謝内科八木 亮夕子(東京都立多摩総合医療センター 薬剤科)
-
透析ケア(1341-1489)2025夏季増刊 Page163-165(2025.06)
2025/07/16
医中誌文献番号:2025224042
【作用機序から患者指導までまるっとわかる 透析室の薬剤カタログ462】(第2章)透析患者が合併する他科疾患の治療薬 痛風・高尿酸血症治療薬早川 兼司(立川メディカルセンター立川綜合病院 薬剤部)
-
日本医事新報(0385-9215)5276号 Page11-43(2025.06)
2025/07/01
医中誌文献番号:2025190059
学び直し 痛風診療久留 一郎(松江市立病院)
-
World J Cardiol. 2025 Jul 26;17(7):106561. doi: 10.4330/wjc.v17.i7.106561.
2025/07/31
Novel cardiac biomarkers and multiple-marker approach in the early detection, prognosis, and risk stratification of cardiac diseases
Bokhari SFH, Umais M, Faizan Sattar SM, Mehboob U, Iqbal A, Amir M, Bakht D, Ali K, Hasan AH, Javed MA, Dost W.
-
Curr Rheumatol Rep. 2025 Jul 30;27(1):32. doi: 10.1007/s11926-025-01199-4.
2025/07/30
Quality Care Assessment in Gout
Kwok TSH, Chandratre P.
-
Arch Toxicol. 2025 Jul 30. doi: 10.1007/s00204-025-04140-x. Online ahead of print.
2025/07/30
NAD(P)(+)-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite
Wu Q, Fang JL, Nagumalli SK, Guo X, Beland FA.
-
J Asthma Allergy. 2025 Jul 25;18:1129-1146. doi: 10.2147/JAA.S529371. eCollection 2025.
2025/07/30
Reactive Oxygen Species in Asthma: Regulators of Macrophage Polarization and Therapeutic Implications: A Narrative Review
Liu Y, Zhang M, Wang T, Zhang J.
-
Plants (Basel). 2025 Jul 15;14(14):2189. doi: 10.3390/plants14142189.
2025/07/30
Green Extract from Pre-Harvest Tobacco Waste as a Non-Conventional Source of Anti-Aging Ingredients for Cosmetic Applications
Leal M, Moreno MA, Orqueda ME, Simirgiotis M, Isla MI, Zampini IC.
-
Pharmaceutics. 2025 Jun 30;17(7):865. doi: 10.3390/pharmaceutics17070865.
2025/07/30
Could Sodium-Glucose Co-Transporter-2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists Play a Role in Gout Treatment?
Kaufmann D, Schlesinger N.
-
Antioxidants (Basel). 2025 Jul 21;14(7):892. doi: 10.3390/antiox14070892.
2025/07/29
Piperine Induces Apoptosis and Cell Cycle Arrest via Multiple Oxidative Stress Mechanisms and Regulation of PI3K/Akt and MAPK Signaling in Colorectal Cancer Cells
Chang WL, Peng JY, Hong CL, Li PC, Chye SM, Lu FJ, Lin HY, Chen CH.
-
Eur J Intern Med. 2025 Jul 26:S0953-6205(25)00312-7. doi: 10.1016/j.ejim.2025.07.028. Online ahead of print.
2025/07/29
Crystal clear - part I: The role of uric acid in cardiorenal disease
Borghi C, Fogacci F, Cicero AF.
-
Front Endocrinol (Lausanne). 2025 Jul 11;16:1623111. doi: 10.3389/fendo.2025.1623111. eCollection 2025.
2025/07/28
Shanling Jiangzhi Tea treats hyperuricemia by inhibition of COMT/MAOA signaling pathway and p53/SERPINE1/NLRP3 signaling pathway
Chen HN, Wu HZ, Yang YF.
-
Nat Commun. 2025 Jul 25;16(1):6861. doi: 10.1038/s41467-025-62172-4.
2025/07/28
Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents
Tejay S, Lorenzana-Carrillo MA, Huang G, Tabatabaei Dakhili SA, Zhao Y-, Eaton F, Mendiola Pla M, Bowles DE, Kinnaird A, Paterson DI, Pituskin E, Ussher JR, Michelakis ED, Sutendra G.
-
Food Chem. 2025 Jul 22;492(Pt 3):145659. doi: 10.1016/j.foodchem.2025.145659. Online ahead of print.
2025/07/28
Impact of high hydrostatic pressure treatment on physicochemical characteristics, structural characteristics, and functional characteristics of mare milk casein
An N, Yang J, Zhao X, Basak P, Zhang Y, Suo H, Song J.
-
J Proteomics. 2025 Jul 23;321:105506. doi: 10.1016/j.jprot.2025.105506. Online ahead of print.
2025/07/28
Redox proteomics workflow to unveil extracellular targets of oxidation in vascular endothelial cells
Vileigas DF, da Silva RP, Dempsey B, Massafera MP, Pinz MP, Meotti FC.
-
Phytomedicine. 2025 Jul 17;145:157079. doi: 10.1016/j.phymed.2025.157079. Online ahead of print.
2025/07/28
Combination of Withania coagulans and Fagonia cretica ameliorates hyperuricemia by re-modulating gut microbiota-derived spermidine and traumatic acid
Naveed M, Atta A, Rui B, Khan I, Xue Q, Zhou M, He X, Walayat B, Alam H, Xu Y, Wu Y, Liu Y, Li M.
-
Metabolites. 2025 Jul 2;15(7):444. doi: 10.3390/metabo15070444.
2025/07/25
Uric Acid in Primary Hyperparathyroidism: Marker, Consequence, or Bystander?
Malagrinò M, Zavatta G.
-
Metabolites. 2025 Jun 20;15(7):424. doi: 10.3390/metabo15070424.
2025/07/25
Uric Acid, Colchicine and Chronic Inflammatory Diseases: A Cardiovascular Perspective
Alunno A, Carubbi F, Ferri C.
-
Diseases. 2025 Jul 7;13(7):213. doi: 10.3390/diseases13070213.
2025/07/25
Uric Acid Causes Pancreatic β Cell Death and Dysfunction via Modulating CHOP-Mediated Endoplasmic Reticulum Stress Pathways
Li X, Chen Y, Su L, He J.
-
Res Sq [Preprint]. 2025 Jul 16:rs.3.rs-6908346. doi: 10.21203/rs.3.rs-6908346/v1.
2025/07/25
Modulation of IRAK4 as a Therapeutic Strategy Against Monosodium Urate- and Xanthine-Induced Inflammation in Macrophages and HepG2 Cells
Umar S, Chang HT, Maienschein-Cline M, Ravindran S.
-
Front Cardiovasc Med. 2025 Jul 10;12:1541307. doi: 10.3389/fcvm.2025.1541307. eCollection 2025.
2025/07/25
A systematic review and network meta-analysis of cardiovascular safety of benzbromarone compared to febuxostat and allopurinol in patients with gout
Lin TS, Lin YL, Hsu CH, Hsieh SC, Shau WY, Yang WS, Chen CL.
-
Eur J Pediatr. 2025 Jul 25;184(8):499. doi: 10.1007/s00431-025-06335-x.
2025/07/25
A prevalent MOCS2 variant in the Roma population is associated with a novel mild form of molybdenum cofactor deficiency
Cho SK, Schwarz G, Tasic V, Křížková M, Krijt J, Roeper J, Honzík T, Šebesta I, Kožich V, Šaligová J, Pavelcova K, Masinova J, Winkler CA, Stiburkova B.
-
Intern Med. 2025 Jul 24. doi: 10.2169/internalmedicine.5926-25. Online ahead of print.
2025/07/25
Back to the Physiology: Renal Tubular Handling of Uric Acid and Emerging Strategies for Managing Hyperuricemia
Takata T, Isomoto H.
-
JBJS Case Connect. 2025 Jul 24;15(3). doi: 10.2106/JBJS.CC.25.00231. eCollection 2025 Jul 1.
2025/07/24
Arthroscopic Treatment of Extension Block in the Knee Caused by Gouty Tophi: A Case Report
Chawanpaiboon P, Voravitvet S, Juntharamussakarn C, Ganokroj P.
-
Rheumatol Int. 2025 Jul 24;45(8):176. doi: 10.1007/s00296-025-05915-2.
2025/07/24
Medication adherence and health empowerment in gout: a cross-sectional survey of patients
Wang H, Yao Y, Lv X, Yu M, Geng S, Yong C.
-
J Biol Inorg Chem. 2025 Aug;30(4-5):329-344. doi: 10.1007/s00775-025-02120-1. Epub 2025 Jul 24.
2025/07/24
Magnetic interactions between metal sites in complex enzymes
Maiti BK, Moura I, Moura JJG.
-
J Manag Care Spec Pharm. 2025 Aug;31(8):795-807. doi: 10.18553/jmcp.2025.31.8.795.
2025/07/24
Group-based trajectory modeling to assess adherence to chronic urate-lowering therapies among commercially insured US adults with gout
Rizk JG, Qato DM, Bingham CO, dosReis S.
-
Exp Physiol. 2025 Jul 23. doi: 10.1113/EP092501. Online ahead of print.
2025/07/24
Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains
Burrage E, Coblentz T, Prabhu SS, Eminhizer NM, Childers R, Bryner RW, Lewis SE, Maxwell BA, DeVallance ER, Kelley EE, Chantler PD.
-
Transplantation. 2025 Jul 24. doi: 10.1097/TP.0000000000005496. Online ahead of print.
2025/07/24
SGLT2 Inhibitors and GLP-1 Receptor Agonists in Kidney Transplantation: A Systematic Review and Meta-Analysis
Lee SA, Verhoeff R, Hullekes F, Hansrivijit P, de Bruin RWF, Porte RJ, Riella LV.
-
Eur J Med Res. 2025 Jul 23;30(1):660. doi: 10.1186/s40001-025-02939-z.
2025/07/24
Development and validation of risk prediction models for acute kidney disease in gout patients: a retrospective study using machine learning
Jiang S, Xu L, Li C, Wang X, Guan C, Wang Y, Che L, Shen X, Xu Y.
-
Curr Issues Mol Biol. 2025 Apr 2;47(4):246. doi: 10.3390/cimb47040246.
2025/07/23
The MAPK Response to Virus Infection Is Modified by Probenecid
Jones LP, Martin DE, Tripp RA.
-
J Mol Histol. 2025 Jul 23;56(4):237. doi: 10.1007/s10735-025-10507-2.
2025/07/23
Exploring the role of xanthine oxidase and aldehyde oxidase in metabolic dysfunction-associated steatotic liver disease (MASLD)
Gupta N, Singh K.
-
Wiad Lek. 2025;78(6):1019-1025. doi: 10.36740/WLek/207359.
2025/07/23
Clinical and laboratory correlates of kidney function in multiple myeloma patients
Savuliak HR, Bardash VO, Maksymets TA, Perepelytsya MV, Kit ZM, Karpyshyn NV, Sklyarov EY.
-
Am J Physiol Cell Physiol. 2025 Aug 1;329(2):C456-C470. doi: 10.1152/ajpcell.00153.2025. Epub 2025 Jun 16.
2025/07/23
Metabolic dysregulation of trained immunity in immune aging and the impact of dietary patterns
Grigorescu A, Riza AL, Streata I, Netea MG.
-
World J Diabetes. 2025 Jul 15;16(7):107673. doi: 10.4239/wjd.v16.i7.107673.
2025/07/23
Extra-renal role of urate transporter-1 in diabetes
Yang TS, Du M, Luo LY, Lin L, Luo XL.
-
Wei Sheng Yan Jiu. 2025 Jul;54(4):540-548. doi: 10.19813/j.cnki.weishengyanjiu.2025.04.003.
2025/07/23
[Associations between dietary approaches to stop hypertension diet and serum uric acid levels and the risk of hyperuricemia:the mediation role of systematic inflammation]
Yang Y, Cai S, Tamas ST, Zhang S, Piao W, Nan J, Li F, Zhao L, Yu D.
-
Bioorg Chem. 2025 Jul 11;163:108745. doi: 10.1016/j.bioorg.2025.108745. Online ahead of print.
2025/07/23
Molecular insights from multi-spectroscopy and computer simulations investigation on the xanthine oxidase inhibition by 2',4'-dimethoxy-4-hydroxychalcone
Yang C, Xu H, Zhao P, Yin Q, Wang N, Li L, Liu Y, Li Y.
-
Chem Biodivers. 2025 Jul 22:e00349. doi: 10.1002/cbdv.202500349. Online ahead of print.
2025/07/23
Phytochemical Profiling and In Silico Molecular Interactions of the Bioactivity-Guided Fractions of Ocimum tenuiflorum L.: A Comprehensive Report of Antioxidant, Anti-Inflammatory, and Anti-Mutagenic Properties
Chatterjee A, Sarkar B.
-
Food Funct. 2025 Jul 22. doi: 10.1039/d5fo01404b. Online ahead of print.
2025/07/23
Insight into the underlying mechanism of functional Pediococcus acidilactici SWU-HX39 in alleviating hyperuricemia
He J, Zhang X, Chen H, Kan J, Awad S, Ibrahim AA, Zalán Z, Du M.
-
Int J Rheum Dis. 2025 Jul;28(7):e70378. doi: 10.1111/1756-185x.70378.
2025/07/23
Clinical Practice Consensus Statement 2025: Management of Hyperuricemia and Gout in Adolescents
Li C, Lu J, Lyu Z, Chen H, Su B, Ban B, Mao J, Liu P, Cheng Z, Zhu J, Wan N, Chen X, Gong C, Ye P, Sun M, Sun W, Zhang H, Yin H, Jiang X, Wang Q, Chen Y, Lin HY, Mi J, Zhao J.
-
Int J Rheum Dis. 2025 Jul;28(7):e70375. doi: 10.1111/1756-185x.70375.
2025/07/22
2024 Update of Chinese Guidelines for Diagnosis and Treatment of Hyperuricemia and Gout Part I: Recommendations for General Patients
Sun M, Lyu Z, Wang C, Li Y, Zhao D, Ran X, Chen H, Su B, Chang X, Liu P, Yan D, Jiang X, Chen K, Shao J, Teng X, Yao Y, Li Y, Chen Y, Cheng J, Cheng Z, Liu Z, Liu F, Li X, Yin H, Liu C, Lin HY, Chen Y, Tsai WC, Yip RML, Li C, Zhao J.
-
WMJ. 2025;124(2):169-172.
2025/07/21
A Case of Allopurinol-Induced Drug Reaction with Eosinophilia and Systemic Symptoms in a Patient With Polycystic Kidney Disease and Chronic Kidney Disease
Koller E, Dixit N, Lee R, Jha P.
-
Geospat Health. 2025 Jul 7;20(2). doi: 10.4081/gh.2025.1380. Epub 2025 Jul 21.
2025/07/21
Spatial Bayesian semi-parametric Cox-Leroux modelling of stroke patient hospitalization: aspects on survival
Aswi A, Poerwanto B, Hammado N, Nurwan N, Oktaviana O, Djawijah S, Cramb S.
-
Phytomedicine. 2025 Jul 16;145:157084. doi: 10.1016/j.phymed.2025.157084. Online ahead of print.
2025/07/20
Rosmarinic acid attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions
Jia L, Sun B, Nie A, Shi Y, Zhou Z, Zhu C.
-
Biomed Pharmacother. 2025 Jul 17;190:118358. doi: 10.1016/j.biopha.2025.118358. Online ahead of print.
2025/07/19
The role of Quercetin in the treatment of kidney diseases: A comprehensive review
Chen P, Rao X, He P, Liu J, Chu Y, Dong Y, Ding M.
-
Mater Today Bio. 2025 Jun 23;33:102019. doi: 10.1016/j.mtbio.2025.102019. eCollection 2025 Aug.
2025/07/18
An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots' specific response to ·OH for aminophylline pharmacokinetic studies
Miao C, Zhang M, Zheng Y, Lin X, Yang S, Xu L, Lu S, Huang Z, Huang J, Zheng Y, Weng S.
-
Nat Prod Res. 2025 Jul 17:1-5. doi: 10.1080/14786419.2025.2534681. Online ahead of print.
2025/07/17
Luteolin phospholipid complexes improves the bioavailability of luteolin and exhibits potent protection and high safety in mice with gouty nephropathy
Mao J, Gao T, Wang L, Lv X, Zhao X.
-
Mycotoxin Res. 2025 Aug;41(3):513-527. doi: 10.1007/s12550-025-00600-6. Epub 2025 Jul 16.
2025/07/17
Aflatoxin B(1)-induced toxicity, oxido-inflammatory damage, and apoptosis in male rat reproductive circuitry were abrogated by co-treating with the xanthophyll-lutein and zeaxanthin
Owumi S, Ishaya JA, Chimezie J, Nnamdi M, Chibuzor J, Joel FO, Babalola JO.
-
Nat Commun. 2025 Jul 16;16(1):6551. doi: 10.1038/s41467-025-61226-x.
2025/07/17
Molecular mechanism of drug inhibition of URAT1
Yu Z, Hu T, Su J, Zhao J, Li R, Ma Q, Chen Q, Bai Q, Dong Y, Yuan P, Li N, Zhang XC, Zhao Y.
-
Bioorg Med Chem Lett. 2025 Jul 14;128:130342. doi: 10.1016/j.bmcl.2025.130342. Online ahead of print.
2025/07/17
Discovery of novel benzomorpholine derivatives as potent URAT1 inhibitors with hypouricemic effects
Wang Y, Zhang L, Shao M, Hou X, Yang Y, Yang Y, Ye F, Li X, Xiao Z.
-
Comput Biol Med. 2025 Jul 15;196(Pt B):110770. doi: 10.1016/j.compbiomed.2025.110770. Online ahead of print.
2025/07/17
Comprehensive clinical and bioinformatics analysis identifies JUN as a related target of Shenling Baizhu San in the treatment of gout
Gao M, Xue Y, Pang L, Li H.
-
BMC Pharmacol Toxicol. 2025 Jul 15;26(1):133. doi: 10.1186/s40360-025-00966-4.
2025/07/16
Manganese mitigates atrazine-induced oxidative stress and hepatorenal toxicity: insights from network pharmacology and in vivo experimentation
Owumi SE, Adedayo TT, Chimezie J, Oluwawibe B, Agbarogie H, Babalola JO, Ogunyemi OM, Arunsi UO, Otunla MT, Irozuru CE, Altayyar A, Ugbogu EA.
-
J Clin Hypertens (Greenwich). 2025 Jul;27(7):e70092. doi: 10.1111/jch.70092.
2025/07/15
The Association Between the Hemoglobin Glycation Index and Cardiometabolic Diseases: A Mini-Review
Wu QY, Mo LR, Nan J, Huang WZ, Wu Q, Su Q.
-
Clin Exp Rheumatol. 2025 Jul 10. doi: 10.55563/clinexprheumatol/eg8gtg. Online ahead of print.
2025/07/14
Seasonal shifts and population characteristics of uric acid in eastern coastal China: a big data analysis from Hangzhou
Chen X, Du J, Ye DL, Xia J, Zhang H.
-
Cardiovasc Toxicol. 2025 Jul 14. doi: 10.1007/s12012-025-10026-2. Online ahead of print.
2025/07/14
Construction of a Machine Learning-Based Clopidogrel Resistance Risk Prediction Model
Wang RY, Yan SD, Zeng JQ, Mu T, Yan Y, Zhao YY, Xie L, Liu LL.
-
Avicenna J Phytomed. 2025 Jul-Aug;15(4):1328-1340. doi: 10.22038/ajp.2024.25277.
2025/07/14
Methanol leaf extract of Azadirachta indica mitigates isoproterenol-induced myocardial infarction through the modulation of oxidative stress, and PPARα and BCL2 signaling in rats
Yusuf AF, Ajibade TO, Esan OO, Asenuga RE, Onoja M, Akpan MO, Badejo JA, Omobowale TO, Oyagbemi AA, Adedapo AA, Oguntibeju OO, Yakubu MA.
-
Front Endocrinol (Lausanne). 2025 Jun 27;16:1599158. doi: 10.3389/fendo.2025.1599158. eCollection 2025.
2025/07/14
Serum uric acid to creatinine ratio and long-term target vessel events in diabetes patients undergoing PCI with drug-eluting stents implantation: a retrospective study
Cui P, Wang S, Zhang Z, Wang R.
-
Int J Mol Sci. 2025 Jul 3;26(13):6413. doi: 10.3390/ijms26136413.
2025/07/13
Influence of Gut Microbiota-Derived Butyrate on Intestinal Uric Acid Excretion and Hyperuricemia Regulation by Cichorium intybus L
Yang Y, Wang Y, Huang J, Xu Y, Yin X, Lin Z, Zhang B.
-
Int J Mol Sci. 2025 Jun 27;26(13):6189. doi: 10.3390/ijms26136189.
2025/07/13
HPLC-DAD-ESI/MS and 2D-TLC Analyses of Secondary Metabolites from Selected Poplar Leaves and an Evaluation of Their Antioxidant Potential
Pobłocka-Olech L, Krauze-Baranowska M, Godlewska S, Kimel K.
-
Int J Mol Sci. 2025 Jun 25;26(13):6115. doi: 10.3390/ijms26136115.
2025/07/13
Evaluating an Early Risk Model for Uncomplicated Hypertension in Pregnancy Based on Nighttime Blood Pressure, Uric Acid, and Angiogenesis-Related Factors
Fernandez-Castro I, Vazquez-Agra N, Alban-Salgado A, Sanchez-Andrade M, Lopez-Casal S, Cruces-Sande A, Seoane-Casqueiro O, Pose-Reino A, Hermida-Ameijeiras A.
-
Nutrients. 2025 Jun 24;17(13):2097. doi: 10.3390/nu17132097.
2025/07/13
Novel Potential Probiotics from Chinese Baijiu Fermentation Grains: Dual Action of Lactiplantibacillus plantarum LTJ1/LTJ48 in Uric Acid Reduction and Gut Microbiota Restoration for Hyperuricemia Therapy in Mice
Zhong F, Feng X, Cao J, Li M, Tian J, Wang J, Wang X, Luo X.
-
Steroids. 2025 Jul 9;221:109657. doi: 10.1016/j.steroids.2025.109657. Online ahead of print.
2025/07/12
Exploring the urate lowering properties of Erigeron annuus Lin. and phytosterol contributions: In vitro assays and in silico approaches
Rana R, Sharma A, Kumar N, Mohanna P, Jyoti, Khanna A, Singh JV, Singh Bedi PM.