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新着論文
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日本筋学会学術集会プログラム・抄録集(2433-975X)11回 Page132(2025.08)
2025/11/01
医中誌文献番号:Z917420097
Xanthine oxidoreductase inhibitor promotes muscle function via ATP salvage and ROS reduction(タイトル和訳中)(英語)白柿 早瞳(東京科学大学/大学院医歯学総合研究科), 本橋 紀夫, 芦田 雪, 鎌谷 直之, 青木 吉嗣
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内科(0022-1961)136巻3号 Page644-647(2025.09)
2025/11/01
医中誌文献番号:2025322620
【最近よく聞く他科の薬-先生の外来にこの薬を使っている患者さんがきますよ】(第9章)糖尿病・代謝・内分泌 痛風・高尿酸血症治療薬(選択的尿酸再吸収阻害薬) ドチヌラド(ユリス)溝口 達也(名古屋市立大学 大学院医学研究科循環器内科学), 瀬尾 由広
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PLoS One. 2025 Nov 18;20(11):e0337091. doi: 10.1371/journal.pone.0337091. eCollection 2025.
2025/11/18
Association of hyperuricemia with coronary heart disease and other cardiovascular outcomes: A systematic review and dose-response meta-analysis
Lyu D, Zhuang R, Li J, Wu Y, Di Y, Song M, Ma L, Li J, Zhang Y.
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Clin Rheumatol. 2025 Nov 18. doi: 10.1007/s10067-025-07750-z. Online ahead of print.
2025/11/18
Machine learning based on systemic inflammation response index and risk of cardiovascular disease in gout: a retrospective study and clinical validation
Zhang Q, Yu XH, Zhang WZ, Lyu XB, Lin HH, Zeng ST, Liu CQ, Huang HJ, Deng WZ.
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Front Nutr. 2025 Oct 31;12:1684829. doi: 10.3389/fnut.2025.1684829. eCollection 2025.
2025/11/17
Effects of barley green on uric acid, inflammatory factors, xanthine oxidase activity and body composition of patients with hyperuricemia: a randomized controlled trial
Cui M, Shao L, Zhao S, Guo Q, Liu X, Liu P.
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Front Endocrinol (Lausanne). 2025 Oct 30;16:1684558. doi: 10.3389/fendo.2025.1684558. eCollection 2025.
2025/11/17
Explainable machine learning model for classifying atherosclerotic cardiovascular disease in patients with metabolic dysfunction-associated steatotic liver disease
Li Z, Chen X, Ren L, Wang B, Ruan S, Wang J, Zhang W.
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J Cachexia Sarcopenia Muscle. 2025 Dec;16(6):e70135. doi: 10.1002/jcsm.70135.
2025/11/17
3D Body Scanning-Derived Normative Values of Appendicular Circumferences: A Novel Tool for Sarcopenia Screening in Chinese Adults
He H, Cheng Q, Zhang Z, Hu Y, Lu Z, Han W, Tu J, Li A, Song Z, Liu Y, Xu T, Chang Q, Ou Q, Pan H, Wang Z, Shan G.
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Med Sci Monit. 2025 Nov 17;31:e949422. doi: 10.12659/MSM.949422.
2025/11/17
Association of Hyperuricemia with Cardiovascular Risk Factors and Cardiac Structural Changes in Patients Undergoing Maintenance Hemodialysis in Southwest China
Pan W, Wu K, Zeng Y, Liang Y, Du X, Hu K, Fan H, Hu Q, Zhang Q.
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Geroscience. 2025 Nov 15. doi: 10.1007/s11357-025-01991-1. Online ahead of print.
2025/11/16
The association between uric acid and incident cardiovascular events amongst healthy, community-dwelling older adults
Lo A, Rickard AJ, Karim N, Tran C, Ryan J, McNeil JJ, Vishwanath S, Zhou Z.
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Eur J Med Res. 2025 Nov 14;30(1):1120. doi: 10.1186/s40001-025-03388-4.
2025/11/15
The association between estimated glucose disposal rate and the prevalence and mortality of chronic kidney disease: a cross-sectional study with linked mortality follow-up
Gao P, Xu S, Zhuo Y, Yan Y, Kamili K, Wang D, Li X, Xing H, Tian G.
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Arthritis Care Res (Hoboken). 2025 Nov 14. doi: 10.1002/acr.25695. Online ahead of print.
2025/11/14
Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout
Richette P, Walter-Petrich A, Nguyen QD, Resche-Rigon M, Nguyen QHD, Do MD, Mai TP, Nguyen TD, Perez-Ruiz F, Letavernier E, Pascart T, Latourte A, Ea HK, Bardin T.
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Front Pharmacol. 2025 Oct 29;16:1654173. doi: 10.3389/fphar.2025.1654173. eCollection 2025.
2025/11/14
Febuxostat may decrease the incidence of COVID-19 infection among patients with gout: a retrospective cohort study
Wang W, Wang SI, Cheng Y, Wang X, Fan Y, Wei JC.
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Redox Biol. 2025 Nov 7;88:103923. doi: 10.1016/j.redox.2025.103923. Online ahead of print.
2025/11/14
The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health as mice age
Dyson N, Khambata RS, Parakaw T, Massimo G, Khuat NH, Noor AA, Gee LC, Lim I, Siddique U, Sullivan AJ, Ho JW, Rathod K, Barnes MR, Cabrera CP, Ahluwalia A.
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Poult Sci. 2025 Nov 8;104(12):106084. doi: 10.1016/j.psj.2025.106084. Online ahead of print.
2025/11/14
Comparative study of the glucolipid profile and GLUTs gene expression in response to insulin treatment across three chicken breeds
Wang ZY, Wang HJ, Du PF, Zhang XL, Zhang L, Li HH, Si XM, Chen W, Zhang HY, Huang YQ.
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Cureus. 2025 Oct 11;17(10):e94371. doi: 10.7759/cureus.94371. eCollection 2025 Oct.
2025/11/13
The Impact of Hyperuricemia on the Progression of Atherosclerotic Cardiovascular Disease
Mdivnishvili M, Kharebashvili M, Chumburidze V, Nadaraia K, Gujejiani L, Virkovi K.
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J Endocr Soc. 2025 Oct 22;9(12):bvaf163. doi: 10.1210/jendso/bvaf163. eCollection 2025 Dec.
2025/11/13
Association of Neck Circumference With Cardiometabolic Risk Factors and Diseases in the German National Cohort
Strathmann EA, Ratjen I, Willrodt K, Enderle J, Schlesinger S, Fischer B, Weber KS, Övermöhle C, Greiser KH, Sedlmeier AM, Heier M, Köttgen A, Günther K, Nauck M, Lieb W.
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Arthritis Rheumatol. 2025 Nov 12. doi: 10.1002/art.43439. Online ahead of print.
2025/11/13
Comment on: Comparative Cardiovascular Safety of NSAID versus Colchicine Use When Initiating Urate-Lowering Therapy Among Patients with Gout: Target Trial Emulations
Huang J.
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Nutrients. 2025 Oct 31;17(21):3447. doi: 10.3390/nu17213447.
2025/11/13
Lactiplantibacillus plantarum WLPL04 from Human Breast Milk Attenuates Hyperuricemia via Coordinated Purine Salvage Pathway, Renal Transporter Regulation, and Gut Microbiota Remodeling
Wei M, Hu Y, Zhang Z, Qiu L, Tao X, Wei H.
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Nutrients. 2025 Oct 27;17(21):3373. doi: 10.3390/nu17213373.
2025/11/13
Functional Properties of Enriched Curd with Collagen and Plant Phytochemicals for Athletes and Physiological Benefits: Evidence Data from Preclinical Trials In Vivo
Zharykbasova K, Kakimov A, Zharykbasov Y, Kakimova Z, Guldana R, Zhanna K, Galiya B, Baigazinov Z, Kovács T, Shahrokhi A.
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Foods. 2025 Oct 30;14(21):3706. doi: 10.3390/foods14213706.
2025/11/13
Limosilactobacillusreuteri Urob-7 Alleviates Hyperuricemia by Modulating Uric Acid Metabolism Through Nucleoside Degradation and Xanthine Oxidase Inhibition
Jing Y, Bai X, Qian H, Wang Y, Hao Y, Zhai Z, Zhang Z, Hao Y.
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Int J Mol Sci. 2025 Oct 28;26(21):10455. doi: 10.3390/ijms262110455.
2025/11/13
Purine Nucleotide Precursors in Preventing Myocardial Ischemia-Reperfusion Injury
Musial PT, Badtke PA, Zabielska-Kaczorowska MA.
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Int J Mol Sci. 2025 Oct 22;26(21):10268. doi: 10.3390/ijms262110268.
2025/11/13
Uric Acid in Cerebral Ischemia: A Systematic Review of Its Biomarker Value and Role in Neuroprotection
Roman-Filip I, Roman-Filip C, Morosanu V, Andone S, Bajko Z, Balasa R.
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Support Care Cancer. 2025 Nov 13;33(12):1054. doi: 10.1007/s00520-025-10090-y.
2025/11/13
Rasburicase vs. allopurinol: mortality in hematological malignancies post anti-hyperuricemic therapy - real-world study
Cairo MS, Gallagher JR, Barnes Y, Drea E, Clark C, Carroll S.
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Probiotics Antimicrob Proteins. 2025 Nov 12. doi: 10.1007/s12602-025-10834-6. Online ahead of print.
2025/11/12
Uric Acid-Reducing Potential of Limosilactobacillus Fermentum FOSU YHD19: A Comprehensive Genomic and Phenotypic Study
Huang F, Lu YH, Xiong J, Zeng XA, Huang YY, Wang LH.
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Front Med (Lausanne). 2025 Oct 27;12:1657274. doi: 10.3389/fmed.2025.1657274. eCollection 2025.
2025/11/12
Evaluation of febuxostat in treating diabetic kidney disease with hyperuricemia: a systematic review and meta-analysis of randomized controlled trials
Lin M, Zhang H, Wu H, Zhao D, Nan Z, Fu Y.
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JMA J. 2025 Oct 15;8(4):1116-1123. doi: 10.31662/jmaj.2025-0129. Epub 2025 Aug 1.
2025/11/12
Serum Uric Acid as a Potential Risk Marker for Atherosclerotic Cardiovascular Disease in Japanese Adults: Using the Hisayama Study-based Prediction Model
Matsuyama T, Yamawaki M, Furuya J, Omata K, Kaneko M, Furuya R, Yasuda H, Fukasawa H.
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Poult Sci. 2025 Nov 4;104(12):106062. doi: 10.1016/j.psj.2025.106062. Online ahead of print.
2025/11/10
A self-designed Chinese herbal formula alleviates GAstV infection-induced gout in goslings by inhibiting xanthine oxidase (XOD) and regulating intestinal microbiota
Zhang X, Zhu M, Cui H, Fan J, Yang M, Jin Y, Mao S, Zhang H.
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Int Immunopharmacol. 2025 Nov 9;168(Pt 1):115805. doi: 10.1016/j.intimp.2025.115805. Online ahead of print.
2025/11/10
Natural drug-derived carbon dots as a novel oral dosing strategy for gouty arthritis
Zhang Y, Ma J, Zou P, Xia M, Wang S, Jin B, Lu Z, Zhai C, Huang H, Zhang Y, Kong H, Qu H, Zhao Y.
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Biol Futur. 2025 Nov 10. doi: 10.1007/s42977-025-00294-y. Online ahead of print.
2025/11/10
Antibacterial, antioxidant, and xanthine-oxidase inhibitory screening studies of selected cyperaceae species occurring in Europe
Dávid CZ, Kincses A, Kiss T, Girst G, Papp L, Hohmann J, Vasas A.
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Naunyn Schmiedebergs Arch Pharmacol. 2025 Nov 10. doi: 10.1007/s00210-025-04787-4. Online ahead of print.
2025/11/10
Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for gout
Liao WQ, Chen HY, Li YY, Xiao LJ, Qiu ZX, Hu SS, He SH, Luo L, Xie JJ, Zhang JY.
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Ren Fail. 2025 Dec;47(1):2570071. doi: 10.1080/0886022X.2025.2570071. Epub 2025 Nov 9.
2025/11/10
Kidney stones and autosomal dominant polycystic kidney disease: a state-of-the-art review
Borghol AH, Azooz M, Bou Antoun MT, Souvalian L, Shami B, Mina J, Munairdjy Debeh FG, Ghanem A, Sandouk H, Rangarajan V, Hanna D, Naranjo CD, Drexler Y, Norouzi S, Noruzi A, Salih M, Klett DE, Porter IE, Dahl NK, Chebib FT.
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Clin Rheumatol. 2025 Nov 9. doi: 10.1007/s10067-025-07783-4. Online ahead of print.
2025/11/09
Health outcomes associated with patient-perceived gout aetiology: a cross-sectional analysis of the GAPP Study baseline data
Selvadurai D, Coleshill MJ, Day RO, Briggs NE, Schulz M, Aung E.
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Comput Biol Chem. 2025 Nov 4;120(Pt 1):108763. doi: 10.1016/j.compbiolchem.2025.108763. Online ahead of print.
2025/11/08
Searching for potential xanthine oxidase inhibitors from Vietnamese herb plants via computational studies
Nguyen AH, Do AT, Linh NN, Pham MQ, Ngo ST, Le TK.
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Cell Cycle. 2025 Nov 7:1-12. doi: 10.1080/15384101.2025.2587234. Online ahead of print.
2025/11/07
Repurposing the anti-gout drug benzbromarone for the treatment of glioma
Huo M, Wang Z, Guo W, Gong J, Lu H, Liu W, Ding L.
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ACR Open Rheumatol. 2025 Nov;7(11):e70111. doi: 10.1002/acr2.70111.
2025/11/07
Firsekibart as a Prophylactic Treatment for Acute Gout Flare in Participants Initiating Urate-Lowering Therapy: A Phase 2, Randomized, Open-Label, Multicenter, Active-Controlled Trial
Yu Y, Xue Y, Hu J, Zhang N, Li R, Guo H, Qian L, Gou W, Yang J, Mao L, Yu J, Liu S, Xu Q, Luo T, Zou H.
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Front Endocrinol (Lausanne). 2025 Oct 22;16:1687289. doi: 10.3389/fendo.2025.1687289. eCollection 2025.
2025/11/07
TyG × waist circumference composite indicator and cardiovascular disease risk in older adults across multiple regions: a cross-sectional study
Guo Y, Zhang J, Chen T, Wang Y, Geng F, Jia H.
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Biochim Biophys Acta Mol Basis Dis. 2026 Feb;1872(2):168102. doi: 10.1016/j.bbadis.2025.168102. Epub 2025 Nov 4.
2025/11/07
Revisiting the metabolic crosstalk between type 2 diabetes and hyperuricemia: Pathophysiological insights and therapeutic perspectives
Xia X, Niu H, Xu C, Liu X, Zhang G, Ling J.
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Front Mol Biosci. 2025 Oct 21;12:1680812. doi: 10.3389/fmolb.2025.1680812. eCollection 2025.
2025/11/06
Superoxide- and semiquinone-linked activation of molecular hydrogen in metal-catalyst-free solution
Ishibashi T, Harunari E, Ishihara G, Niiyama T, Noda-Urata M, Komori N.
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Cardiovasc Ther. 2025 Oct 28;2025:8419343. doi: 10.1155/cdr/8419343. eCollection 2025.
2025/11/06
Antiatherogenic and Cardioprotective Effects of a Xanthine Derivative KMUP-1 in ApoE Knockout Mice
Sulistyowati E, Huang SE, Hsu CC, Wu YC, Chao YY, Hsu JH, Wu BN, Dai ZK, Lin MC, Yeh JL.
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Clin Case Rep. 2025 Nov 4;13(11):e71381. doi: 10.1002/ccr3.71381. eCollection 2025 Nov.
2025/11/06
Dual-Energy CT Demonstrates Multiple Urate Crystal Deposits in the Sternoclavicular Joint, Cricoid Cartilage, and Cervical Ligaments
Zhang C, Wang Z, Zhang Z, Jia E.
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BMC Nephrol. 2025 Nov 5;26(1):618. doi: 10.1186/s12882-025-04504-6.
2025/11/06
Association between serum uric acid levels and primary aldosteronism
Zhao X, Jiao H, Zhang R, Zhao H, Ma L, Jia Z, Tang Z, Gu Y.
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BMJ Open Diabetes Res Care. 2025 Nov 4;13(6):e005135. doi: 10.1136/bmjdrc-2025-005135.
2025/11/06
Metabolic factors moderate the association between hepatic fibrosis and atherosclerotic cardiovascular risk in type 2 diabetes
Lu L, Gao C, Wu N, He S, Liu Y, Zhang N, Zhou J.
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Chem Biodivers. 2025 Nov 5:e02169. doi: 10.1002/cbdv.202502169. Online ahead of print.
2025/11/05
Phytochemical and Computational Discovery of Potent Xanthine Oxidase Inhibitors From Ziziphus lotus L. Leaves and Seeds
Bellahcene F, Benarous K, Erol E, Serseg T, Topçu G, Linani A, Bouakkaz H, Kaouka A, Yousfi M.
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Front Pharmacol. 2025 Oct 21;16:1642121. doi: 10.3389/fphar.2025.1642121. eCollection 2025.
2025/11/05
Qifu Huazhuo formula for gout recurrence prevention: an interim analysis combining clinical outcomes with proteomic and metabolomic profiling
Shen Z, Zhu F, Chu Y, Wang H, Wang M, Chen X, Xiao Y, Yang Y, Huang R.
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Food Sci Nutr. 2025 Nov 2;13(11):e71150. doi: 10.1002/fsn3.71150. eCollection 2025 Nov.
2025/11/05
Effects of Whey Protein Hydrolysate Ingestion on Serum Uric Acid Levels in Adult Men: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study
Somoto Y, Okuno A, Nomaguchi K, Nakano M, Tanaka M, Kakiuchi I, Nakamura M, Sakane N.
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Medicine (Baltimore). 2025 Oct 17;104(42):e45285. doi: 10.1097/MD.0000000000045285.
2025/11/05
Serum uric acid and the risk of hypertension in a Middle Eastern cohort: A 10-year prospective study discovering BMI-mediated associations and gender-specific vulnerabilities
Sarebanhassanabadi M, Mirjalili SR, Marques-Vidal P, Namayandeh SM, Mirshamsi A.
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BMC Med. 2025 Nov 4;23(1):609. doi: 10.1186/s12916-025-04454-8.
2025/11/05
Development and validation of a multidimensional and interpretable artificial intelligence model to predict gout recurrence in hospitalised patients: a real-world, ambispective multicentre cohort study in China
Li M, Zhang H, Chen S, Zhong F, Liu J, Wu J, Lin R, Li R, Wu Y, Xie D, Zhang K, Zheng B, Chen X, Cheng Z, Jiang Y, Ye H, Cai L, Xie R, Li D, Zhu J, Li J.
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J Agric Food Chem. 2025 Nov 19;73(46):29551-29565. doi: 10.1021/acs.jafc.5c05340. Epub 2025 Nov 4.
2025/11/05
Artificial Intelligence-Aided Virtual Screening and Molecular Dynamics Analysis of Novel Xanthine Oxidase Inhibitory Peptides Derived from Sunflower (Helianthus annuus) Proteins
Wang K, Liu M, Zhang Y, Li W, Han W.
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Acc Chem Res. 2025 Nov 4. doi: 10.1021/acs.accounts.5c00614. Online ahead of print.
2025/11/04
Assembly-Driven Chemistry of Magnetic Nanoparticles: From Structural Design to Biomedical Applications
Wang Q, Gan Y, Li F, Ling D.
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Photochem Photobiol Sci. 2025 Nov;24(11):1857-1873. doi: 10.1007/s43630-025-00811-x. Epub 2025 Nov 3.
2025/11/04
Pre-treatment with caffeic acid-phthalimide prevents UVB-induced oxidative stress and cytotoxicity
da Silva BTA, Chagas VS, Rodrigues RB, Ximenes VF, Nakamura CV, Sueli de Oliveira Silva L.
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BMC Cardiovasc Disord. 2025 Nov 3;25(1):784. doi: 10.1186/s12872-025-05262-x.
2025/11/04
Gender differences in the predictive value of serum uric acid for major adverse cardiovascular events in patients with acute coronary syndromes: a retrospective cohort study
Guo C, Lin N, Cao A, Han C, Jin Q, Liu Y, Bian X, Shan F, Sun Z, Zhang S, Chen X.
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J Atheroscler Thromb. 2025 Oct 31. doi: 10.5551/jat.65980. Online ahead of print.
2025/11/04
Association of Serum Soluble T-cadherin Levels with Metabolic Syndrome in Japanese Participants Undergoing Health Checkups
Mineo R, Fukuda S, Iioka M, Nishizawa H, Kawada K, Kondo Y, Obata Y, Nagao H, Fujishima Y, Fujimoto T, Yamamoto K, Matsuzawa Y, Shimomura I.
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Front Cardiovasc Med. 2025 Oct 17;12:1616677. doi: 10.3389/fcvm.2025.1616677. eCollection 2025.
2025/11/03
Metabolic perturbations in cardiomyopathies: implications for early diagnosis and targeted interventions
Al-Shahrabi R, Al Mansoori G, Al-Saffar M, Akawi N.
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J Agric Food Chem. 2025 Nov 12;73(45):28823-28837. doi: 10.1021/acs.jafc.5c08467. Epub 2025 Nov 2.
2025/11/03
SCFAs-Enriching Kiwifruit-Derived Synbiotic Reprograms Microbiota to Suppress XOD and Promote Urate Clearance
Wang Q, Pu X, Song Y, Lv Z, Hao J, Yuan T, Wang Y, Liu X, Guo R, Liu Z.
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Ultrason Sonochem. 2025 Oct 19;123:107630. doi: 10.1016/j.ultsonch.2025.107630. Online ahead of print.
2025/11/03
Ultrasound-driven antisolvent precipitation for engineered naringenin ultrafine crystals with potent xanthine oxidase inhibitory and bacteriostatic effects
Huang Y, Weng C, Zeng F, Dai X, Qiu X, Lin J, Peng B, Zhang X, Liu Z.
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Biochemistry (Mosc). 2025 Oct;90(10):1388-1396. doi: 10.1134/S0006297925602278.
2025/11/02
Alpha- and Gamma-Synucleins Regulate Energy Metabolism and Xanthine Oxidase Activity in Brain Cells
Fedulina AA, Seryogina ES, Krayushkina AM, Chaprov KD, Vinokurov AY, Abramov AY.
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Biochem Pharmacol. 2025 Oct 30;243(Pt 1):117487. doi: 10.1016/j.bcp.2025.117487. Online ahead of print.
2025/11/01
Hyperuricemia exacerbates acetaminophen hepatotoxicity via JNK activation and mitophagy reduction
Liu Y, Peng B, Li D, Chen J, Lai Y, You Y, Jiang Z, Zhou X, Wu C, Chen L, Kwan HY, Yu L, Zuo D, Zhao X.
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兵庫医科大学医学会雑誌(0385-7638)50巻1号 Page47-58(2025.09)
2025/11/16
医中誌文献番号:Z926210005
血清尿酸と動脈硬化早期指標との関連 CAVI(心臓足首血管指数)による検討 篠山研究小西 雅美(丹波篠山市役所), 久保田 芳美, 東山 綾, 丸茂 幹雄, 山下 好子, 岡村 智教, 宮本 恵宏, 若林 一郎
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Rp.+(2760-3598)24巻4号 Page106-117(2025.10)
2025/11/16
医中誌文献番号:2025344040
【見逃すと激ヤバ?キケンの芽を察知し回避せよ!徹底審議ハイリスク処方】処方カスケード編 治療方針を見直したいリスク未評価な処方箋 現場でみられる処方カスケード 本来ならば不要な薬剤が追加されるまで袴田 潤(慶応義塾大学医学部附属病院 薬剤部), 木村 元範, 末廣 直哉
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Rp.+(2760-3598)24巻4号 Page049-051(2025.10)
2025/11/16
医中誌文献番号:2025344022
【見逃すと激ヤバ?キケンの芽を察知し回避せよ!徹底審議ハイリスク処方】激ヤバ事例編 黙って素通りしてはいけないハイリスク処方箋 腎機能低下編 アザチオプリンとアロプリノールの併用 禁忌じゃない方!アザチオプリンの代謝阻害古久保 拓(白鷺病院 薬剤科)
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Chem Biodivers. 2025 Nov 29:e02314. doi: 10.1002/cbdv.202502314. Online ahead of print.
2025/11/29
In Vitro and In Silico Assessment of Datura stramonium Flower Alkaloids as Multi-Target Inhibitors of Biofilm Formation, Xanthine Oxidase, and Tyrosinase Enzymes
El-Saeid AF, Helal IE, El-Baz R, Sallam A, Badria FA.
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J Med Case Rep. 2025 Nov 28;19(1):626. doi: 10.1186/s13256-025-05691-4.
2025/11/29
Kiesselbach's area nasal septal gouty tophus with an integrated "3 + 2" diagnostic algorithm: a case report
Chen W, Chen W, Guo D, Wang Z, Shi Z, Zhong J.
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BMC Cardiovasc Disord. 2025 Nov 28;25(1):850. doi: 10.1186/s12872-025-05197-3.
2025/11/29
Nonlinear relationship between the serum uric acid-to-high density lipoprotein cholesterol ratio and short-term readmission in chronic heart failure: a retrospective cohort study
Guo L, Liu P, Cai L, Hu L, Zhou Y.
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Probiotics Antimicrob Proteins. 2025 Nov 28. doi: 10.1007/s12602-025-10854-2. Online ahead of print.
2025/11/28
Purine-Degrading Lactic Acid Bacteria Isolated from Fermented Foods and Fig Fruit: Evaluation of Probiotic and Anti-Hyperuricemic Properties
Asjad T, Al-Adeeb A, Sibomana M, Basharat S, Bux E, Gu Q, Yu X.
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J Med Chem. 2025 Nov 28. doi: 10.1021/acs.jmedchem.5c02404. Online ahead of print.
2025/11/28
Novel Isoidide Subunit-Containing Xanthine Oxidase Inhibitors with Potent Hypouricemic Effects
Zeng X, Chen Y, Xu B, Zhang J, Huang K, Meng Y, Lu J, Wang L, Qin M.
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Cureus. 2025 Oct 27;17(10):e95499. doi: 10.7759/cureus.95499. eCollection 2025 Oct.
2025/11/28
Febuxostat Versus Allopurinol Use in Gout Patients: A Real-World Study
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Aging Health Res. 2025 Sep;5(3):100235. doi: 10.1016/j.ahr.2025.100235. Epub 2025 May 22.
2025/11/28
Associations between Traditional Chinese Medicine Body Constitution and Cardiovascular Disease Risk in a White population
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Drugs Real World Outcomes. 2025 Nov 27. doi: 10.1007/s40801-025-00526-6. Online ahead of print.
2025/11/27
Effectiveness and Safety of the Novel Selective Urate Reabsorption Inhibitor Dotinurad After Switching from Febuxostat in Patients with Stage B/C Heart Failure
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Minerva Endocrinol (Torino). 2025 Nov 27. doi: 10.23736/S2724-6507.25.04366-0. Online ahead of print.
2025/11/27
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Nutrients. 2025 Nov 11;17(22):3518. doi: 10.3390/nu17223518.
2025/11/27
Exploring the Role of Plant-Based Nutrition in Polycystic Kidney Disease
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Pharmaceutics. 2025 Nov 11;17(11):1454. doi: 10.3390/pharmaceutics17111454.
2025/11/27
Colon-Specific Delivery of Probenecid Enhances Therapeutic Activity of the Uricosuric Agent Against Rat Colitis
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Int J Mol Sci. 2025 Nov 14;26(22):11010. doi: 10.3390/ijms262211010.
2025/11/27
Combined Oral Contraceptives and the Risk of Thrombosis
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2025/11/27
From Electron Imbalance to Network Collapse: Decoding the Redox Code of Ischemic Stroke for Biomarker-Guided Precision Neuroprotection
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2025/11/27
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2025/11/27
Phytochemical Characterisation and Antioxidant and Anti-Inflammatory Potential of Muscari neglectum (Asparagaceae) Bulbs
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Biomedicines. 2025 Nov 5;13(11):2716. doi: 10.3390/biomedicines13112716.
2025/11/27
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2025/11/27
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Biomedicines. 2025 Oct 23;13(11):2595. doi: 10.3390/biomedicines13112595.
2025/11/27
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2025/11/27
In Vivo Studies on the Interaction Between Orally Administered Nitrite and Omeprazole: Beyond Proton-Catalyzed S-Nitrosation
Rebelo MA, Cássia-Barros A, Conde-Tella SO, Frugeri SF, Ovidio PP, Jordão Junior AA, Kayzuka C, Lacchini R, Silva AO, Tirapellli CR, Feelisch M, Tanus-Santos JE.
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2025/11/27
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2025/11/27
Dandelion Leaf Aqueous Extract Relieves Hyperuricemia and Its Complications via Modulating Uric Acid Metabolism, Renal Inflammation, and Gut Microbes
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2025/11/27
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2025/11/26
Lycopene Mitigates Rat Liver Damage Induced by Lipopolysaccharide via Mechanisms Involving Oxidative Stress, Inflammation, and Apoptosis
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2025/11/26
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2025/11/26
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Zhang H, Liu J, Lin R, Xie D, Lin W, Zhang Q, Zhong F, Chen S, Huang Q, Zhang M, Chen Y, Chen X, Cheng Z, Xu J, Cai L, Xia X, Chen Y, Xu Z, Yuan Y, Li M, Li J.
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BMC Cardiovasc Disord. 2025 Nov 25;25(1):839. doi: 10.1186/s12872-025-05322-2.
2025/11/26
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Sci Rep. 2025 Nov 25;15(1):41847. doi: 10.1038/s41598-025-25877-6.
2025/11/26
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2025/11/26
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2025/11/25
Analysis of arrhythmia and its risk factors in patients with COVID-19
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Chem Biodivers. 2025 Nov 25:e02470. doi: 10.1002/cbdv.202502470. Online ahead of print.
2025/11/25
In Vitro Xanthine Oxidase Inhibition, DNA Protection, Anti-Inflammatory, Antioxidant Activity, Phytochemical Analysis, and In Silico Studies of Punica granatum Peels and Flowers
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2025/11/25
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2025/11/25
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Sci Rep. 2025 Nov 24;15(1):41697. doi: 10.1038/s41598-025-25624-x.
2025/11/25
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In Silico Pharmacol. 2025 Nov 21;13(3):189. doi: 10.1007/s40203-025-00476-5. eCollection 2025.
2025/11/24
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Disruption of Proteoglycan 4 (PRG4)-CD44 Signaling Modulates Chronic Synovitis in Conditionally Inactivated Mice
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ACS Omega. 2025 Nov 7;10(45):53775-53790. doi: 10.1021/acsomega.5c01520. eCollection 2025 Nov 18.
2025/11/24
Investigating the Antioxidant, Pro-Inflammatory Enzyme Inhibitory, Neuroprotective, and Antineuroinflammatory Bioactives of Osbeckia octandra Using In Vitro and In Silico Approaches: A Pilot Study
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2025/11/22
Ultrasound-detected crystal depositions and clinical flares dissolve during successful urate-lowering therapy: 5-year follow-up results from the treat-to-target NOR-Gout study
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Photodiagnosis Photodyn Ther. 2025 Nov 19:105286. doi: 10.1016/j.pdpdt.2025.105286. Online ahead of print.
2025/11/22
Evaluating the Impact of Febuxostat on 5-Aminolevulinic Acid-Based Photodynamic Therapy in Bladder Cancer Cell Lines
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2025/11/21
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2025/11/21
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2025/11/21
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2025/11/20
Allopurinol Versus Febuxostat Use and the Risk of Cardiovascular Disease in People With Chronic Kidney Disease: A New-User Active Comparator Cohort Study
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Medicine (Baltimore). 2025 Oct 31;104(44):e45466. doi: 10.1097/MD.0000000000045466.
2025/11/20
Analysis of the efficacy of UBE in the treatment of tophus deposition within the lumbar spinal canal
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2025/11/20
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2025/11/20
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2025/11/19
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2025/11/19
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2025/11/19
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Eur J Med Res. 2025 Nov 18;30(1):1135. doi: 10.1186/s40001-025-03407-4.
2025/11/19
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2025/11/19
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Li H, Liu C, Chen P, Wang S, Li X, Luo X, Xie Y, Wang X, Wang L.
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2025/11/19
Influence of xanthine oxidase and inosine monophosphate dehydrogenase polymorphisms on 6-mercaptopurine treatment response in pediatric acute lymphoblastic leukemia
Sabirova Z, Boucetta MTE, Bensouyad RR, Gagné V, Théorêt Y, Nava T, Leclerc JM, Laverdière C, Sinnett D, Tran TH, Krajinovic M.

