本コンテンツは、医療従事者にとって有用な学術情報をお届けすることを目的としており、
公平な立場から一定のキーワードを元に選択した高尿酸血症や痛風に関する記事をお届けしています。
一部、国内での承認外の情報が含まれることもありますが、これを推奨するものではありません。
また、特定の薬剤の処方誘引あるいは企業の営利を企図するものではありません。
治療、各薬剤の使用にあたっては最新の製品添付文書をご参照ください。
論文タイトルを押すとPubmedもしくは医中誌Webへ移動します。
※なお、医中誌Web利用には会員登録が必要になります。
新着論文
-
防衛衛生(0006-5528)71巻別冊 Page61(2023.12)
2024/09/16
医中誌文献番号:Y709030133
尿酸輸送体遺伝子ABCG2変異による痛風・高尿酸血症の発症リスクの解析を通した、ゲノム個別化看護実装に向けての検討早野 貴美子(防衛医科大学校 地域看護学講座), 中山 昌喜, 竹花 奈々, 三浦 美千瑠, 菊池 理園, 鳥羽 美帆, 清水 聖子, 上野 美紀, 松尾 洋孝
-
防衛衛生(0006-5528)71巻別冊 Page27(2023.12)
2024/09/16
医中誌文献番号:Y709030017
女性の血清尿酸値上昇に及ぼすABCG2機能低下の影響の定量的解析 閉経・肥満・飲酒・加齢との比較三好 優香(防衛医科大学校 衛生学公衆衛生学講座), 中島 宏, 中山 昌喜, 橋本 逸美, 河村 優輔, 清水 聖子, 豊田 優, 上野 美紀, 早野 貴美子, 四ノ宮 成祥, 角田 正史, 松尾 洋孝
-
ビタミン(0006-386X)98巻5-6号 Page323-324(2024.06)
2024/09/01
医中誌文献番号:Y627240011
病因・病態解明を目指した酵素研究 キサンチン酸化還元酵素と痛風・筋萎縮性側索硬化症草野 輝男(日本医科大学 生化学・分子生物学)
-
Rheumatology (Oxford). 2024 Sep 18:keae514. doi: 10.1093/rheumatology/keae514. Online ahead of print.
2024/09/18
Non-adherence to urate lowering therapy in gout after 5 years is related to poor outcomes-results from the NOR-Gout study
Uhlig T, Karoliussen LF, Sexton J, Provan SA, Haavardsholm EA, Dalbeth N, Hammer HB.
-
J Am Heart Assoc. 2024 Sep 18:e034136. doi: 10.1161/JAHA.123.034136. Online ahead of print.
2024/09/18
Association of the Triglyceride-Glucose Index With Resistant Hypertension and a Nomogram Model Construction
Yang HT, Liu JK, Liu BQ, Yang Y, Xie X.
-
Drug Saf. 2024 Sep 17. doi: 10.1007/s40264-024-01485-7. Online ahead of print.
2024/09/18
Drug-Induced Hypouricemia
Ben Salem C, Agrebi M, Sahnoun D, Fathallah N, Hmouda H.
-
Gut Microbes. 2024 Jan-Dec;16(1):2399213. doi: 10.1080/19490976.2024.2399213. Epub 2024 Sep 17.
2024/09/17
Empowering probiotics with high xanthine transport for effective hyperuricemia management
Zou ZP, Li JL, Zhang YF, Zhou Y, Ye BC.
-
Medicine (Baltimore). 2024 Sep 13;103(37):e39698. doi: 10.1097/MD.0000000000039698.
2024/09/17
Sleep disorders are closely associated with coronary heart disease in US adults (≥20 years): A cross-sectional study
Gan TM, Yang YJ, Mo GL, Wang SR, Li SH, Li JY.
-
J Matern Fetal Neonatal Med. 2024 Dec;37(1):2399304. doi: 10.1080/14767058.2024.2399304. Epub 2024 Sep 17.
2024/09/17
Fetoplacental unit involvement in uric acid production in women with severe preeclampsia: a prospective case control pilot study
Shenhav S, Harel I, Solt I, Shenhav A, Fytlovich S, Aharoni D, Rimler A, Anteby EY, Ovadia YS.
-
J Ethnopharmacol. 2024 Sep 14;337(Pt 1):118817. doi: 10.1016/j.jep.2024.118817. Online ahead of print.
2024/09/17
Mechanism of Biqi capsules in the treatment of gout based on network pharmacology and experimental verification
Li G, Du S, Yan S, Wang Y, Bu R, Cheng M, Zhang Y, Chen Q, Wu Y, Zhang X, Wang D, Wang T.
-
Pharmacol Ther. 2024 Sep 14;263:108723. doi: 10.1016/j.pharmthera.2024.108723. Online ahead of print.
2024/09/17
Organic anion transporters in remote sensing and organ crosstalk
Granados JC, Nigam SK.
-
Metabol Open. 2024 Aug 26;23:100312. doi: 10.1016/j.metop.2024.100312. eCollection 2024 Sep.
2024/09/17
Hyperuricemia and associated factors among hypertensive patients attending an academic hospital of Ethiopia: A cross-sectional study
Philmon Daka O, Bekele Jember T, Hunie Tesfa K.
-
Front Endocrinol (Lausanne). 2024 Aug 30;15:1405301. doi: 10.3389/fendo.2024.1405301. eCollection 2024.
2024/09/16
Incidence and risk factors for amputation in Chinese patients with diabetic foot ulcers: a systematic review and meta-analysis
Zhang Y, Liu H, Yang Y, Feng C, Cui L.
-
Int J Biol Macromol. 2024 Sep 13;280(Pt 1):135550. doi: 10.1016/j.ijbiomac.2024.135550. Online ahead of print.
2024/09/16
Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice
Zhang N, Zhang B, Chen X, Zhang Y, Wang Y, Lu S, Zhang H, Chen Y, Jiang H, Zhou H.
-
Nutrients. 2024 Sep 9;16(17):3042. doi: 10.3390/nu16173042.
2024/09/14
Lactiplantibacillus plantarum 06CC2 Enhanced the Expression of Intestinal Uric Acid Excretion Transporter in Mice
Nei S, Matsusaki T, Kawakubo H, Ogawa K, Nishiyama K, Tsend-Ayush C, Nakano T, Takeshita M, Shinyama T, Yamasaki M.
-
Molecules. 2024 Aug 29;29(17):4098. doi: 10.3390/molecules29174098.
2024/09/14
Carbon Nanomaterials with SOD-like Activity: The Effect of the Ionic Strength
Veloso AD, Videira RA, Oliveira MC.
-
Clin Exp Med. 2024 Sep 13;24(1):220. doi: 10.1007/s10238-024-01488-9.
2024/09/14
Utility of serum uric acid levels in excluding pulmonary hypertension in severe chronic lung disease: insights from a tertiary care center
Izhakian S, Gorenshtein A, Engelstein H, Freidkin L, Rosengarten D, Eldar O, Kramer MR.
-
Free Radic Res. 2024 Sep 12:1-16. doi: 10.1080/10715762.2024.2400674. Online ahead of print.
2024/09/12
The inhibitory potential of 4,7-dihydroxycoumarin derivatives on ROS-producing enzymes and direct HOO(•)/o(2)(•) - radical scavenging activity - a comprehensive kinetic DFT study
Milanović Ž, Jeremić S, Antonijević M, Dimić D, Nakarada Đ, Avdović E, Marković Z.
-
Intern Med. 2024 Sep 11. doi: 10.2169/internalmedicine.3517-24. Online ahead of print.
2024/09/12
Prediction for Risk of Hypouricemia in Hospitalized Patients: A Single-center, Retrospective Cohort Study
Hisatome I, Tomita K, Kato R, Ikeuchi T, Touge H, Hamada T, Goto T, Ninomiya H, Otani N, Kuwabara M, Miyazaki S, Yamasaki A.
-
Food Chem X. 2024 Aug 22;23:101755. doi: 10.1016/j.fochx.2024.101755. eCollection 2024 Oct 30.
2024/09/11
Evaluation of physicochemical characteristics, bioactivity, flavor profile and key metabolites in the fermentation of goji juice by Lacticaseibacillus rhamnosus
An X, Li T, Hu J, Li Y, Liu H, Fang H, Wei X.
-
Clin Res Cardiol. 2024 Sep 10. doi: 10.1007/s00392-024-02537-9. Online ahead of print.
2024/09/11
The association between gout and subsequent cardiovascular events: a retrospective cohort study with 132,000 using propensity score matching in primary care outpatients in Germany
Sedighi J, Luedde M, Gaensbacher-Kunzendorf J, Sossalla S, Kostev K.
-
J Agric Food Chem. 2024 Sep 25;72(38):21065-21076. doi: 10.1021/acs.jafc.4c05855. Epub 2024 Sep 10.
2024/09/11
Presence of Flazin in Miso and Identification of Four Tryptophan-Derived ß-Carbolines Formed during Fermentation
Li YJ, Zhang YP, Chiu PC, Lin SM, Lee C, Lo CY, Lien WT, Chiou RY.
-
Nutr J. 2024 Sep 10;23(1):104. doi: 10.1186/s12937-024-01007-2.
2024/09/10
Sex-specific associations between total and regional Fat-to-muscle Mass ratio and cardiometabolic risk: findings from the China National Health Survey
Lu Z, Hu Y, Chen X, Ou Q, Liu Y, Xu T, Tu J, Li A, Lin B, Liu Q, Xi T, Wang W, Huang H, Xu D, Chen Z, Wang Z, He H, Shan G.
-
ChemistryOpen. 2024 Sep 9:e202400127. doi: 10.1002/open.202400127. Online ahead of print.
2024/09/09
An Improved Test Method for Assaying the Inhibition of Bioflavonoids on Xanthine Oxidase Activity in vitro
Yao Y, Wu T, Zhang M, Fu D, Yang H, Chen S.
-
Cell Res. 2024 Sep 9. doi: 10.1038/s41422-024-01023-1. Online ahead of print.
2024/09/09
Transport mechanism and structural pharmacology of human urate transporter URAT1
Dai Y, Lee CH.
-
Gene. 2024 Sep 4;933:148920. doi: 10.1016/j.gene.2024.148920. Online ahead of print.
2024/09/07
Exosomal miRNAs in patients with chronic heart failure and hyperuricemia and the underlying mechanisms
Chen Z, Shi J, Huang X, Yang Y, Cheng Y, Qu Y, Gu N.
-
Food Chem. 2025 Jan 1;462:141030. doi: 10.1016/j.foodchem.2024.141030. Epub 2024 Aug 29.
2024/09/07
Human milk fat globule delivers entrapped probiotics to the infant's gut and acts synergistically to ameliorate oxidative and pathogenic stress
Yadav M, Mallappa RH, Ambatipudi K.
-
Am J Physiol Regul Integr Comp Physiol. 2024 Sep 6. doi: 10.1152/ajpregu.00127.2024. Online ahead of print.
2024/09/06
Modulation of cutaneous vasodilation by reactive oxygen species during local and whole-body heating in young and older adults
McGarr GW, Li-Maloney C, King KE, Janetos KT, Fujii N, Amano T, Kenny GP.
-
Mod Rheumatol. 2024 Sep 5:roae056. doi: 10.1093/mr/roae056. Online ahead of print.
2024/09/05
Efficacy and safety of febuxostat in Japanese paediatric patients with hyperuricaemia including gout: phase 2, single arm, open‑label, multicentre studies
Ito S, Morita Y, Nitami M, Iwama R, Nakajima A, Yamanaka H, Honda M.
-
Curr Med Chem. 2024 Sep 4. doi: 10.2174/0109298673300632240823061848. Online ahead of print.
2024/09/05
Diuretic and Anti-hyperuricemic Effects of Geranyl Acetate in Rats
Shah SN, Younis W, Junior AG, Manzoor W, Malik MNH, Mushtaq MN, Munir MU, Bashir A, Bibi S, Talha M, Livero FADR.
-
J Nippon Med Sch. 2024;91(4):352-356. doi: 10.1272/jnms.JNMS.2024_91-403.
2024/09/05
Effect of Dotinurad on Serum Uric Acid Concentration in Chronic Kidney Disease Patients Treated with Febuxostat
Yamada T, Sakai Y, Kurihara O, Kashiwagi T, Iwabu M.
-
Hormones (Athens). 2024 Sep 4. doi: 10.1007/s42000-024-00593-4. Online ahead of print.
2024/09/04
Clinical application of cluster analysis in patients with newly diagnosed type 2 diabetes
Wang Y, Chen H.
-
Front Endocrinol (Lausanne). 2024 Aug 20;15:1452896. doi: 10.3389/fendo.2024.1452896. eCollection 2024.
2024/09/04
Oxidative stress mediates the association between triglyceride-glucose index and risk of cardiovascular and all-cause mortality in metabolic syndrome: evidence from a prospective cohort study
Yang M, Shangguan Q, Xie G, Sheng G, Yang J.
-
Rev Cardiovasc Med. 2024 Aug 16;25(8):289. doi: 10.31083/j.rcm2508289. eCollection 2024 Aug.
2024/09/04
Unraveling Changes of Brachial Artery Residual Stress and Its Relationship to Cardiovascular Disease Risk Factors
Chen J, Jin L, Sha L, Cao M, Du L, Li Z, Luo X.
-
Ital J Pediatr. 2024 Sep 4;50(1):161. doi: 10.1186/s13052-024-01732-8.
2024/09/04
Is lipoprotein(a) measurement important for cardiovascular risk stratification in children and adolescents?
Giussani M, Orlando A, Tassistro E, Torresani E, Lieti G, Patti I, Colombrita C, Bulgarelli I, Antolini L, Parati G, Genovesi S.
-
South Med J. 2024 Sep;117(9):539-542. doi: 10.14423/SMJ.0000000000001730.
2024/09/04
Diagnosis of Gout as a Correlative Risk for Acute Myocardial Infarction in the Absence of Traditional Cardiovascular Risk Factors
Munshi RF, Pellegrini JR Jr, Olson S, Sodoma AM, Anand P, Hai O, Zeltser R, Makaryus AN.
-
Echocardiography. 2024 Sep;41(9):e15911. doi: 10.1111/echo.15911.
2024/09/03
Is cardiac function associated with the clinical course of disease in patients with gout? A prospective study
Dong Y, Li Y, Liu C, Guo Y, Feng Y.
-
Heliyon. 2024 Aug 13;10(16):e36210. doi: 10.1016/j.heliyon.2024.e36210. eCollection 2024 Aug 30.
2024/09/03
Validation and stability analysis of guanine deaminase assay kit
Sun Q, Gao H, Liu Y, Wang L, Huang J.
-
Heliyon. 2024 Aug 9;10(16):e36024. doi: 10.1016/j.heliyon.2024.e36024. eCollection 2024 Aug 30.
2024/09/03
Hyperuricemia drives intestinal barrier dysfunction by regulating gut microbiota
Yang X, Liu D, Zhao X, Han Y, Zhang X, Zhou Q, Lv Q.
-
Turk J Pharm Sci. 2024 Sep 2;21(4):259-266. doi: 10.4274/tjps.galenos.2023.47650.
2024/09/03
Altered Levels of Gene Expression of Drug Metabolism Enzymes in Rat Brain Following Kainic Acid Treatment
Yalçın A, Turunç E, Armağan G, Kanıt L.
-
Sci Rep. 2024 Sep 2;14(1):20380. doi: 10.1038/s41598-024-71733-4.
2024/09/03
Evaluation of the relationship between xanthine oxidase activity and metabolic syndrome in a population group in Bangladesh
Ali N, Taher A, Islam N, Sarna NZ, Islam F.
-
Chem Biol Interact. 2024 Aug 31;403:111220. doi: 10.1016/j.cbi.2024.111220. Online ahead of print.
2024/09/03
Salinomycin, a potent inhibitor of XOD and URAT1, ameliorates hyperuricemic nephropathy by activating NRF2, modulating the gut microbiota, and promoting SCFA production
Chen YJ, Guo ZT, Chen HQ, Zhang SF, Bao YX, Xie Z, Ke JL, Ye WJ, Liang JC, Chen JC, Li N, Zheng FX, Liao H, Wu T, Pang JX.
-
Acta Pharm Sin B. 2024 Aug;14(8):3591-3604. doi: 10.1016/j.apsb.2024.04.019. Epub 2024 Apr 24.
2024/09/02
Inhibition of xanthine oxidase alleviated pancreatic necrosis via HIF-1α-regulated LDHA and NLRP3 signaling pathway in acute pancreatitis
Rong J, Han C, Huang Y, Wang Y, Qiu Q, Wang M, Wang S, Wang R, Yang J, Li X, Hu C, Chen Z, Deng L, Huang W, Xia Q, Du D.
-
Neuropsychiatr Dis Treat. 2024 Aug 27;20:1629-1639. doi: 10.2147/NDT.S471744. eCollection 2024.
2024/09/02
Metabolic Disturbances in a Mouse Model of MPTP/Probenecid-Induced Parkinson's Disease: Evaluation Using Liquid Chromatography-Mass Spectrometry
Wang Y, Lv B, Fan K, Su C, Xu D, Pan J.
-
Diabetes Obes Metab. 2024 Sep 2. doi: 10.1111/dom.15895. Online ahead of print.
2024/09/02
Effects of ertugliflozin on uric acid and gout-related outcomes in persons with type 2 diabetes and cardiovascular disease: Post hoc analyses from VERTIS CV
Sridhar VS, Cosentino F, Dagogo-Jack S, McGuire DK, Pratley RE, Cater NB, Noyes Essex M, Mancuso JP, Zhao Y, Cherney DZI.
-
J Mol Histol. 2024 Aug 31. doi: 10.1007/s10735-024-10252-y. Online ahead of print.
2024/09/01
Metformin protects against small intestine damage induced by diabetes and dunning's prostate cancer: A biochemical and histological study
Dagsuyu E, Koroglu P, Bulan OK, Gul IB, Yanardag R.