本コンテンツは、医療従事者にとって有用な学術情報をお届けすることを目的としており、
公平な立場から一定のキーワードを元に選択した高尿酸血症や痛風に関する記事をお届けしています。
一部、国内での承認外の情報が含まれることもありますが、これを推奨するものではありません。
また、特定の薬剤の処方誘引あるいは企業の営利を企図するものではありません。
治療、各薬剤の使用にあたっては最新の製品添付文書をご参照ください。
論文タイトルを押すとPubmedもしくは医中誌Webへ移動します。
※なお、医中誌Web利用には会員登録が必要になります。
新着論文
-
The Journal of Physiological Sciences(1880-6546)75巻2号 Page j.jphyss.2025.100029(2025.07)
2025/10/01
医中誌文献番号:Z820440013
Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice(タイトル和訳中)(英語)Mitsubayashi Takao(Department of Physiology, Tsurumi University School of Dental Medicine), Suita Kenji, Ohnuki Yoshiki, Ishikawa Misao, Ito Aiko, Matsuo Ichiro, Miyamoto Go, Abe Mariko, Morii Akinaka, Mototani Yasumasa, Nariyama Megumi, Matsubara Ren, Hayakawa Yoshio, Okumura Satoshi
-
ペインクリニック(0388-4171)46巻8号 Page839-849(2025.08)
2025/10/01
医中誌文献番号:2025294332
【代謝性疾患に伴う痛み】痛風に伴う痛み藤島 裕也(大阪大学 大学院医学系研究科内分泌・代謝内科学講座), 西澤 均, 前田 法一
-
調剤と情報(1341-5212)31巻10号 Page1826-1834(2025.07)
2025/10/01
医中誌文献番号:2025294094
【「基礎」から「知りたい情報」まで 新・薬物アレルギーの教科書】(第3章)薬疹 薬剤性過敏症症候群(DIHS/DRESS)水川 良子(杏林大学 医学部皮膚科学教室)
-
LiSA(1340-8836)32巻8号 Page748-750(2025.08)
2025/10/01
医中誌文献番号:2025293779
症例ライブラリー 波形を読む 消化管穿孔の麻酔導入時にSpO2が低下神谷 諭史(広島大学病院 麻酔科)
-
Immun Inflamm Dis. 2025 Oct;13(10):e70286. doi: 10.1002/iid3.70286.
2025/10/15
U-Shaped Relationship Between White Blood Cell Counts and Incident Hypertension in Military Young Adults: The CHIEF Study, 2014-2020
Tsai KZ, Hong CW, Chang YC, Huang WC, Sui X, Lavie CJ, Lin GM.
-
ACS Med Chem Lett. 2025 Sep 17;16(10):1986-1996. doi: 10.1021/acsmedchemlett.5c00398. eCollection 2025 Oct 9.
2025/10/15
Design, Synthesis, and Biological Evaluation of Triazole-Linked Lignan-Monoterpenoid-Based Hybrid Molecules as Xanthine Oxidase Inhibitors with Potent In Vivo Efficacy
Singh K, Singh A, Malhan A, Guleria M, Khanna A, Sharma A, Parth, Jyoti, Sharma R, Singh H, Jain SK, Bedi PMS.
-
Front Endocrinol (Lausanne). 2025 Sep 29;16:1641699. doi: 10.3389/fendo.2025.1641699. eCollection 2025.
2025/10/15
Multi-dimensional roles of sodium-glucose cotransporter 2 inhibitors: beyond hypoglycemic and cardiorenal protection
Li S, Wang Y, Gong Q.
-
Medicine (Baltimore). 2025 Oct 10;104(41):e45041. doi: 10.1097/MD.0000000000045041.
2025/10/15
Inverse and nonlinear relationships between Life's Essential 8 metrics and gout risk: A cross-sectional study
Cheng Y, Feng Y, Huang M, Zhang L, Lin J, Zhao J, Li C.
-
Pediatr Nephrol. 2025 Oct 14. doi: 10.1007/s00467-025-06961-5. Online ahead of print.
2025/10/15
Factors influencing serum uric acid levels and their impact on cardiovascular risk in patients with pediatric chronic kidney disease
Cho MH, Kang HG, Ahn YH, Kim SH, Park E, Lee JH, Jung J, Cho MH, Baek HS, Shin JI, Lee KH, Han KH, Cho H, Song JY, Kim JH, Yang EM.
-
Nat Prod Res. 2025 Oct 14:1-9. doi: 10.1080/14786419.2025.2571079. Online ahead of print.
2025/10/14
LC-MS(n) analysis, antioxidant activity and in-vivo toxicology of methanolic extract of aerial parts from Calendula aegyptiaca
Grati W, Tahri A, Bouzayani B, Samet S, Ayachi A, Jallouli D, Ayadi F, Ben Mahmoud L, Zeghal KM, Rebai T, Treilhou M, Téné N, Sahnoun Z, Mezghani-Jarraya R.
-
Nat Prod Res. 2025 Oct 14:1-9. doi: 10.1080/14786419.2025.2571851. Online ahead of print.
2025/10/14
Isolation and structural elucidation of new 8-O-4' neolignan and phenolic glucoside from the lianas of gnetum montanum markgr
Do TNV, Nguyen HX, Nguyen NT, Nguyen MTT.
-
J Virol. 2025 Oct 14:e0103125. doi: 10.1128/jvi.01031-25. Online ahead of print.
2025/10/14
Nephropathogenic infectious bronchitis virus induces epithelial-mesenchymal transition of renal tubular epithelial cells through the TGF-β/p-P38 pathway causing uric acid excretion disorder in chickens
Chen Y, Shi Y, Huang C, Huang H, Zeng Y, Cai G, Zheng Z, Liu P, Gao X, Guo X.
-
Arthritis Care Res (Hoboken). 2025 Oct 13. doi: 10.1002/acr.25663. Online ahead of print.
2025/10/14
Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: comment on article by Sun W et al
Gadekallu SHR.
-
Arthritis Care Res (Hoboken). 2025 Oct 13. doi: 10.1002/acr.25664. Online ahead of print.
2025/10/14
Reply to "Febuxostat use is associated with a significantly greater risk of mild to moderate perturbation of liver function compared to benzbromarone in patients with gout: comment on the article by Sun et al"
Sun W, Cui L, Li C.
-
Sci Rep. 2025 Oct 13;15(1):35704. doi: 10.1038/s41598-025-19468-8.
2025/10/14
Systemic immune-inflammation index and uric acid mediate the association between obesity and hypertension in young and middleaged adults
Zuo C, Shen ZD, Lu Y.
-
Med Glas (Zenica). 2025 Aug 25;22(2):201-206. doi: 10.17392/1972-22-02.
2025/10/13
Comparison of coronary artery calcium scores between patients with and without type 2 diabetes
Babić M, Babić Jušić Z, Prevljak S, Zukić F, Bećirović M, Bećirović A, Abdić A, Bećirović E.
-
Front Med (Lausanne). 2025 Sep 26;12:1670282. doi: 10.3389/fmed.2025.1670282. eCollection 2025.
2025/10/13
Untargeted metabolomics reveals distinct biomarkers and metabolic alterations in familial and non-genetic hypercholesterolemia in Saudi patients
Al Mahdi HB, Shaik NA, Awan Z, Daghistani H, Alandejani F, Alghamdi KS, Obaid AA, Zahed R, Hassan RN, Edris S, Banaganapalli B, Mujalli A.
-
Food Sci Nutr. 2025 Oct 11;13(10):e70985. doi: 10.1002/fsn3.70985. eCollection 2025 Oct.
2025/10/13
Polygonatum sibiricum Delar. ex Redoute: A Potential Functional Food for the Prevention and Treatment of Hyperuricemia
Zhao P, Liu W, He M, Cao W, Xu Q, Hao Q, Wang L, Liu Y, Wang J, Wang F, Jiang L, Li S, Dai C, Zheng Q, Ma J, Fan X, Han J.
-
Food Sci Nutr. 2025 Oct 9;13(10):e70982. doi: 10.1002/fsn3.70982. eCollection 2025 Oct.
2025/10/13
The Role of the Intestinal Microbiome in the Pathogenesis and Treatment of Hyperuricemia: A Review
Yang J, Chen J, Liu Z, Qu Y, Yue X, Yuan B, Li M.
-
Clin Lab. 2025 Oct 1;71(10). doi: 10.7754/Clin.Lab.2025.250337.
2025/10/13
A Case of Drug-Induced CA72-4 Pseudo-Elevation and Analysis of Its Causes
Sun HG, Zhang JQ, Zhang Y.
-
Nutr Metab Cardiovasc Dis. 2025 Sep 12:104359. doi: 10.1016/j.numecd.2025.104359. Online ahead of print.
2025/10/13
The effect of low-dose febuxostat on arterial stiffness in elderly patients with asymptomatic hyperuricemia: A prospective, longitudinal cohort study
Lai X, Zhou G, Zhu Q, Zhu Y, Gao B, Lai H, Feng L, Zhou Q.
-
Int J Biol Macromol. 2025 Oct 10;331(Pt 1):148214. doi: 10.1016/j.ijbiomac.2025.148214. Online ahead of print.
2025/10/12
Modulation of NLRP3 inflammasome and uric acid metabolism by small molecule pectin from Premna ligustroides Hemsl leaves: Implications for hyperuricemia management
Deng L, He R, Mao J, Yang H, Shi Q, Peng Y, Zhong G.
-
Poult Sci. 2025 Sep 30;104(12):105927. doi: 10.1016/j.psj.2025.105927. Online ahead of print.
2025/10/12
Development and mechanism of an XOD-targeting fermented traditional Chinese medicine formula for gout prevention in goslings
Zhang Z, Tian Z, Bian C, Tang F, Sun Y, Zhang M, Kang Y, Ning Y, Ma H, Zhang X, Qiao H.
-
Phytomedicine. 2025 Oct 3;148:157368. doi: 10.1016/j.phymed.2025.157368. Online ahead of print.
2025/10/12
Isobavachin alleviates hyperuricemia-induced bone loss by GPR35-NLRP3 signal
Cen X, Mai S, Huang R, Lin S, Chen Y, Zhang S, Zhao P, Guo D, Liang X, Zhao Y, Feng H, Xiao Z, Lu X, Wan H, Wang H, Xie D, Pang J, Zhang Q.
-
Hum Mol Genet. 2025 Oct 11:ddaf151. doi: 10.1093/hmg/ddaf151. Online ahead of print.
2025/10/11
Genetic variants associated with gout identified through a genome-wide study in the UK biobank (N = 150 542)
Tao Y, Cai T, Pan Q, Yang L, Lin S, Haque M, Dottorini T, Abhishek A, Meng W.
-
Food Res Int. 2025 Nov;220:117048. doi: 10.1016/j.foodres.2025.117048. Epub 2025 Jul 30.
2025/10/11
Ultrasound-assisted betaine-based natural deep eutectic solvents for green extraction of total phenols and flavonoids from Lithocarpus litseifolius: Mechanistic insights and anti-hyperuricemic applications
Wang Z, Wang S, Chen Y, Liang L, Yang L, Zeng L.
-
Food Chem. 2025 Sep 18;495(Pt 2):146350. doi: 10.1016/j.foodchem.2025.146350. Online ahead of print.
2025/10/10
Lactiplantibacillus plantarum-mediated bioconversion of blue honeysuckle juice amplifies phenolics to inhibit xanthine oxidase and reshapes volatile metabolome
Liu JY, Ruan W, Yu H, Huo JW, Meng XC, Yue YX.
-
Life Metab. 2025 Jul 31;4(6):loaf031. doi: 10.1093/lifemeta/loaf031. eCollection 2025 Dec.
2025/10/10
A reductive uric acid degradation pathway in anaerobic bacteria
Li Z, Meng W, Gao Z, Peng W, Hu Z, Zhang J, Wang Y, Wu X, Zhao Z, Zhang C, Tang Z, Nie Z, Wu S, Wu B, Zheng H, Luo D, Tong Y, Hu Y, Hu Z, Wei Y, Zhang Y.
-
Eur J Med Res. 2025 Oct 9;30(1):942. doi: 10.1186/s40001-025-03209-8.
2025/10/10
Molecular interplay between TXNIP and GLUT9 underlies uric acid transport dysregulation in vitro under hyperuricemic stress
Zhu Y, Zhang B, He Y, Du M, Chen W, Chen X, Yang Q, Kahaer M, Sun Y.
-
Sci Rep. 2025 Oct 9;15(1):35307. doi: 10.1038/s41598-025-19388-7.
2025/10/10
Diabetes mediates the association between uric acid to high-density lipoprotein cholesterol ratio and abdominal aortic calcification: a cross-sectional study
Li Y, Bai L.
-
Biochem Pharmacol. 2025 Dec;242(Pt 4):117408. doi: 10.1016/j.bcp.2025.117408. Epub 2025 Oct 9.
2025/10/10
Roles of an endogenous peptide ELABELA in ameliorating hyperuricemia by inhibiting uric acid production via CYP27A1-modulated bile acid metabolism in mice
Leng Y, Xie T, Tao Y, Zeng Y, Zhu Q, Wang L.
-
PLoS One. 2025 Oct 9;20(10):e0332827. doi: 10.1371/journal.pone.0332827. eCollection 2025.
2025/10/09
Combined metabolomics and proteomics analysis of vascular cognitive impairment in hypertensive rats induced by endothelial injury
Zhang X, Chang S, Liu J, Wang D.
-
Inflammopharmacology. 2025 Oct 9. doi: 10.1007/s10787-025-01997-3. Online ahead of print.
2025/10/09
URAT1 and GLUT9 as drug targets in gout: progress in transporter-directed therapies and delivery technologies
Mishra S, Harwansh RK, Mazumder R.
-
Kidney Dis (Basel). 2025 Jul 25;11(1):595-609. doi: 10.1159/000547641. eCollection 2025 Jan-Dec.
2025/10/09
Disease Burden of Chronic Kidney Disease in China (1990-2021): An Analysis for the Global Burden of Disease Study 2021
Huang Y, Ye P, Wen L, Pan X, Chen J, Xu Y.
-
Cureus. 2025 Sep 7;17(9):e91789. doi: 10.7759/cureus.91789. eCollection 2025 Sep.
2025/10/09
Characteristics and Outcomes of IgA Nephropathy Patients With SGLT2 Inhibitor-Induced Polycythemia
Furuto Y, Namikawa A, Sato D, Shibuya Y.
-
Eur J Pharm Sci. 2025 Nov 1;214:107313. doi: 10.1016/j.ejps.2025.107313. Epub 2025 Oct 6.
2025/10/09
Febuxostat-aloperine co-amorphous drug delivery system with enhanced water solubility and binding affinity to xanthine oxidase
Guo N, Liu Z, Wu Y, Yuan S, Wei N, Liu Y, Xu H, Chen H.
-
Int J Biol Macromol. 2025 Oct 6:148050. doi: 10.1016/j.ijbiomac.2025.148050. Online ahead of print.
2025/10/09
Inhibition of xanthine oxidase by two aldehydes: Inhibitory kinetics, molecular simulation, inhibition mechanism, and cellular insights
Wang X, Chen B, Wu S, Luo X, Bhullar KS, Zhang Y, Liu H, Wang C, Liu C, Wang Q, He H, Yang H, Su D.
-
Food Chem. 2025 Oct 2;495(Pt 3):146610. doi: 10.1016/j.foodchem.2025.146610. Online ahead of print.
2025/10/09
Accumulation of flavor precursors and markers belonging to different primary processing Coffea arabica beans
Wang H, Wang Y, Li Y, Zhao W, Pang J, Liang W.
-
Am J Hematol. 2025 Oct 8. doi: 10.1002/ajh.70086. Online ahead of print.
2025/10/08
Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications
Liang P, Wan YS, Shan KZ, Chou R, Zhang Y, Delahunty M, Khandelwal S, Francis SJ, Arepally GM, Telen MJ, Yang H.
-
Braz J Med Biol Res. 2025 Oct 6;58:e14729. doi: 10.1590/1414-431X2025e14729. eCollection 2025.
2025/10/08
Associations between serum uric acid levels and hypotension after general anesthesia induction in hypertensive patients
Zhang Y, Wan J, Nie G.
-
Int Marit Health. 2025;76(3):210-215. doi: 10.5603/imh.106257.
2025/10/07
How do cardiologists see seafarers?
Jacuś B, Michnowska W, Szafran-Dobrowolska J, Grześk G, Renke M.
-
Medicine (Baltimore). 2025 Oct 3;104(40):e45055. doi: 10.1097/MD.0000000000045055.
2025/10/07
Sex differences in the association of UA/HDL-c ratio with mortality risk in the general population: An observational study from 1999 to 2018 NHANES data
Zhou W, Jiang H, Lu H.
-
J Inherit Metab Dis. 2025 Nov;48(6):e70092. doi: 10.1002/jimd.70092.
2025/10/07
Allopurinol Treatment Improves Cognitive Skills, Adaptive Behavior, and Biochemical Markers in Young Patients With Adenylosuccinate Lyase Deficiency
Rousselot-Pailley B, Semeraro M, Marquant F, Robel L, Gitiaux C, Kaminska A, Mochel F, Bakouboula P, Elie C, Hennequin C, Ceballos-Picot I, Sanquer S, de Lonlay P.
-
BMC Pharmacol Toxicol. 2025 Oct 6;26(1):157. doi: 10.1186/s40360-025-01001-2.
2025/10/07
Bioequivalence evaluation of generic febuxostat versus Feburic(®) in healthy Chinese subjects: a randomized crossover study
Wang F, Ye X, Li F, Kong H, Liao M, Kan M, Zhuang J, Wang A, Meng X.
-
ACR Open Rheumatol. 2025 Oct;7(10):e70128. doi: 10.1002/acr2.70128.
2025/10/07
Correction to "Gout Remission With Pegloticase-Induced Intensive Urate-Lowering Therapy: A Post Hoc Clinical Trial Analysis"
-
Rheumatol Adv Pract. 2025 Sep 1;9(4):rkaf102. doi: 10.1093/rap/rkaf102. eCollection 2025.
2025/10/06
Association between gout, hyperuricaemia and Parkinson's disease risk: a cohort study in western Sweden (2001-2017)
Dehlin M, Bergquist F, Drivelegka P, Sandström TZ, Jacobsson LTH.
-
Front Nutr. 2025 Sep 18;12:1591472. doi: 10.3389/fnut.2025.1591472. eCollection 2025.
2025/10/06
A cross-sectional exploration of the dietary inflammation index association with cardiovascular disease in gout: application of machine learning algorithms
Zhang Q, Lyu XB, Liu CQ, Zhang WZ, Wang YG, Deng WZ, Yu XH.
-
Ann Med. 2025 Dec;57(1):2568722. doi: 10.1080/07853890.2025.2568722. Epub 2025 Oct 6.
2025/10/06
Uric acid as a potential biomarker for cardiomyopathy in dystrophinopathy
Li Z, Chen X, Yang Z, Ou Y, Wen Y, Zhang C, Peng Y, Lai M, Zhang H.
-
Acta Med Indones. 2025 Jul;57(3):346-352.
2025/10/06
Correlation of Serum FT4 with Serum Uric Acid and Comparison of Uric Acid in Subjects with and without Atrial Fibrillation in Graves' Disease: A Cross-Sectional Study
Yunita B, Subekti I, Karim B, Abdullah M, Rumende CM, Purnamasari D, Kurniawan J, Susilo A.
-
Inflammopharmacology. 2025 Oct 4. doi: 10.1007/s10787-025-01998-2. Online ahead of print.
2025/10/04
Silybum marianum seeds mitigate pro-inflammatory functions of human neutrophils and alleviate ulcerative colitis in rats
Kouki A, Marrouchi R, Souli A, Bouabdallah S, Ferjani W, Dang PM, Dicko A, El-Benna J, Ben-Attia M.
-
Nat Prod Res. 2025 Oct 4:1-8. doi: 10.1080/14786419.2025.2568203. Online ahead of print.
2025/10/04
Fatty acid profile and biological activity of supercritical fluid extract of Rosa canina L. seeds
Ibba A, Rosa A, Fais A, Era B, Porcedda S, Piras A.
-
Cureus. 2025 Aug 31;17(8):e91354. doi: 10.7759/cureus.91354. eCollection 2025 Aug.
2025/10/03
A Preventable Adverse Reaction: Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome Following Allopurinol Use for Asymptomatic Hyperuricemia
Ibrahim H, Rashwan G, Jumani A, Purra H, Alteneiji A, Hussaini S.
-
Sr Care Pharm. 2025 Oct 1;40(10):379-389. doi: 10.4140/TCP.n.2025.379.
2025/10/03
Perspectives on the Management of Hyperuricemia and Gout in Older Adults
Carter MW, Roman YM.
-
BMC Med Educ. 2025 Oct 2;25(1):1320. doi: 10.1186/s12909-025-07886-1.
2025/10/03
Chinese medical students' perceptions of gout: a pilot study
Wang Y, Wang Y, Yin Y, Han X, Xu N, Zhang Y, Zeng X.
-
Front Microbiol. 2025 Sep 16;16:1660938. doi: 10.3389/fmicb.2025.1660938. eCollection 2025.
2025/10/02
Screening of Jiangshui-originated lactic acid bacteria with high hypoglycemic properties and study on functional properties of Jerusalem artichoke Jiangshui
Gui YW, Jin QK, Yao H, Sheteiwy MS, Mohammed AE, Alotaibi MO, Chang SJ, Meng XG.
-
Smart Mol. 2025 Jun 11;3(3):e20250002. doi: 10.1002/smo.20250002. eCollection 2025 Sep.
2025/10/02
Curcumin ameliorates hyperuricemia and gout-induced damage via modulating the ROS-dependent NEK7-NLRP3 inflammasome activation
Zhao Z, Tong X, Sun J, Lu J, Zhang G, Wang Q, Yang L.
-
Clin Exp Pediatr. 2025 Oct 2. doi: 10.3345/cep.2025.01032. Online ahead of print.
2025/10/02
HLA‒B*58:01 and skin reactions in pediatric hematology and oncology patients treated with allopurinol
Maneechai P, Ratanatharathron C, Buaboonnam J, Sanpakit K.
-
Nat Rev Rheumatol. 2025 Nov;21(11):671-683. doi: 10.1038/s41584-025-01302-0. Epub 2025 Oct 1.
2025/10/02
Glucagon-like peptide-1 receptor agonists in arthritis: current insights and future directions
Karacabeyli D, Lacaille D.
-
J Rheumatol. 2025 Nov 1:jrheum.2025-0122. doi: 10.3899/jrheum.2025-0122. Online ahead of print.
2025/10/02
Do Monosodium Urate Crystals Reduce at Different Rates in Joints and Tendons During Urate-Lowering Therapy? A Dual-Energy Computed Tomography Study
Mulqueen W, Gamble G, Doyle A, Mihov B, Horne A, Drake J, Stamp LK, Dalbeth N.
-
Food Chem. 2025 Sep 26;495(Pt 3):146548. doi: 10.1016/j.foodchem.2025.146548. Online ahead of print.
2025/10/02
Identification of antioxidant peptides from a bioactive peptide database PWDB of walnut family protein hydrolysates
Zhang T, Zheng D, Qian S, Du M, Li C, Sun Z, Lü L, Huang J, Zhang L, Wang Z.
-
J Dermatolog Treat. 2025 Dec;36(1):2562299. doi: 10.1080/09546634.2025.2562299. Epub 2025 Oct 1.
2025/10/01
Clinical efficacy, drug retention and recurrence of ixekizumab across psoriasis severities: a multicenter retrospective analysis of 354 patients
Qiao Z, Chai B, Chen Y, Jin HZ, Yang B, Li F, Shi Y, Gu J, Guo Q, Wu L, Lu T, Dang L, Kang X, Liu X.
-
J Health Popul Nutr. 2025 Sep 30;44(1):345. doi: 10.1186/s41043-025-01085-w.
2025/10/01
Study on the association between dietary patterns and cardiovascular metabolic comorbidities among adults
Mao D, He L, Li Y, Zhang M, Wang X, Li G, Liu X, Wang S, Ma M, Ren X.
-
BMC Cancer. 2025 Sep 30;25(1):1472. doi: 10.1186/s12885-025-14960-w.
2025/10/01
Predictors of quality of life in multiple myeloma patients: a multi-centered cross-sectional study
Abu Hamdeh N, Alnees M, Ewidat O, Zahran A, AbuAlrub I, Najajra D, Darwish A, Zraiq S, Bali B, Hadya F, Khaleel A, Ihmoud F, Alzirei K, Salah Q, Yaghmour R, Salloum O, Marrawani M, Zayed A, Ahmad MM, AbuAlsuod E, Shaheen L, Allaham S, Riyad N, Ismail S, Barq A, Atallah S, Alawna A, Abdul-Hafez HA, Masu'd M, Dweikat OAA, Abu Khadija H.
-
Therapeutic Research(0289-8020)46巻8号 Page517-520(2025.08)
2025/10/16
医中誌文献番号:Z904020003
高尿酸血症を有する慢性腎臓病症例に対する選択的尿酸再吸収阻害薬ドチヌラドの効果前田 和夫(前田内科医院)
-
臨床皮膚科(0021-4973)79巻9号 Page683-687(2025.08)
2025/10/16
医中誌文献番号:Z826160014
長期間診断されなかった慢性結節性痛風の1例佐藤 瑞季(伊勢崎市民病院 皮膚科), 長谷川 道子, 田村 敦志
-
日本獣医学会学術集会講演要旨集(1347-8621)167回 Page184(2024.08)
2025/10/16
医中誌文献番号:Z723230146
希少糖D-アロースにより発現誘導されるハマダラカ中腸のキサンチンデヒドロゲナーゼ(XDH)の機能解析水島 大貴(自治医科大学 医学部感染・免疫学講座医動物学部門), 山本 大介, Tabbai Ahmed, 新井 明治, 加藤 大智
-
調剤と情報(1341-5212)31巻12号 Page2184-2187(2025.09)
2025/10/01
医中誌文献番号:2025313088
【高尿酸血症患者に対するライフスタイル指導】高尿酸血症患者に対するライフスタイル指導 ロサルタン,フェノフィブラートの尿酸値低下作用と実際藏城 雅文(大阪公立大学 大学院医学研究科代謝内分泌病態内科学)
-
調剤と情報(1341-5212)31巻12号 Page2179-2182(2025.09)
2025/10/01
医中誌文献番号:2025313087
【高尿酸血症患者に対するライフスタイル指導】高尿酸血症患者に対するライフスタイル指導 SGLT2阻害薬と尿酸値細山田 真(帝京大学 薬学部人体機能形態学研究室)
-
調剤と情報(1341-5212)31巻12号 Page2174-2178(2025.09)
2025/10/01
医中誌文献番号:2025313086
【高尿酸血症患者に対するライフスタイル指導】服薬フォローアップの勘所宮田 大資(東京大学医学部附属病院 薬剤部), 高田 龍平
-
調剤と情報(1341-5212)31巻12号 Page2153-2162(2025.09)
2025/10/01
医中誌文献番号:2025313083
【高尿酸血症患者に対するライフスタイル指導】プリン体だけじゃない! 尿酸値に関する新常識福内 友子(帝京大学 薬学部臨床分析学研究室)
-
調剤と情報(1341-5212)31巻12号 Page2148-2152(2025.09)
2025/10/01
医中誌文献番号:2025313082
【高尿酸血症患者に対するライフスタイル指導】高尿酸血症患者に対して,薬局で何をみて,どう関わるか桑原 政成(自治医科大学地域医療学センター 公衆衛生学)
-
Geroscience. 2025 Oct 31. doi: 10.1007/s11357-025-01979-x. Online ahead of print.
2025/10/31
Leukocyte telomere length and risk of heart failure with preserved ejection fraction in high-risk Chinese patients with hypertension under 65 years
Zhang A, Tang Z, Chang ACY, Gu J, Zhang J, Zhuo Y, Zhang H.
-
Eur J Nutr. 2025 Oct 31;64(8):310. doi: 10.1007/s00394-025-03831-6.
2025/10/31
Association of added sugar intake and its forms with hyperuricemia in general adults: the TCLSIH cohort study
Zhang J, Tong P, Zhai M, Yu H, Wang D, Gu Y, Meng G, Zhang Q, Liu L, Wu H, Wu X, Zhu D, Chen Y, Wang D, Wang Y, Jiao L, Geng H, Sun S, Wang X, Jia Q, Song K, Niu K.
-
Naunyn Schmiedebergs Arch Pharmacol. 2025 Oct 31. doi: 10.1007/s00210-025-04723-6. Online ahead of print.
2025/10/31
Diphenyl diselenide promotes antioxidant activity and reduces apoptosis, offering hepatorenal protection in Wistar rats exposed to diethyl nitrosamine
Owumi S, Emmanuel PD, Chimezie J, Joel FO, Idris B, Babalola JO, Owoeye O.
-
Front Nutr. 2025 Oct 15;12:1677560. doi: 10.3389/fnut.2025.1677560. eCollection 2025.
2025/10/31
Aloe-emodin attenuates hyperuricemia-induced renal injury in mice by mitigating inflammation and oxidative stress
Wang S, Zhu Q, Zhang C, Hu S, Liu D, Yu J, Liu X, Chen Y, Jiang G.
-
Front Endocrinol (Lausanne). 2025 Oct 15;16:1557225. doi: 10.3389/fendo.2025.1557225. eCollection 2025.
2025/10/31
Characteristics of the gut microbiome of asymptomatic hyperuricemia
Cao F, Yi W, Wu M, Gao A, Kang T, Hou X.
-
Front Endocrinol (Lausanne). 2025 Oct 15;16:1687023. doi: 10.3389/fendo.2025.1687023. eCollection 2025.
2025/10/31
Construction and validation of a multimodal predictive model incorporating catecholamines and uric acid for early detection of hypertensive organ damage
Wang M, Zhao H, Li D.
-
Rheumatology (Oxford). 2025 Oct 30:keaf577. doi: 10.1093/rheumatology/keaf577. Online ahead of print.
2025/10/30
Incidence and risk of nephrolithiasis with uricosuric therapies for the treatment of gout: a systematic review and meta-analysis of randomised controlled trials and cohort studies
Dahanayake C, Bajpai R, Lambie M, Jordan KM, Roddy E.
-
BMC Cardiovasc Disord. 2025 Oct 29;25(1):779. doi: 10.1186/s12872-025-05260-z.
2025/10/30
Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial
Mohammadi SG, Shafie D, Feizi A, Bagherniya M, Ahmadi AR, Kafeshani M.
-
Front Endocrinol (Lausanne). 2025 Oct 13;16:1668516. doi: 10.3389/fendo.2025.1668516. eCollection 2025.
2025/10/29
Exploring unsupervised learning techniques for early detection of myocardial ischemia in type 2 diabetes
Liu B, Hou YJ, Wu P, Han X, Qi H, Yang XY, Wu ZF, Li SJ.
-
J Clin Med. 2025 Oct 12;14(20):7186. doi: 10.3390/jcm14207186.
2025/10/29
Persistent Liver Manifestations in Allopurinol-Induced Sweet's Syndrome: An Uncommon Case Report
Papanikolopoulou A, Siasiakou SM, Pantazopoulos K, Trontzas IP, Fyta E, Fiste O, Syrigou E, Syrigos N.
-
Int J Mol Sci. 2025 Oct 14;26(20):9980. doi: 10.3390/ijms26209980.
2025/10/29
Antihyperuricemic Effects of Cornus officinalis Extract via URAT1 Regulation and Renoprotective Mechanisms
Sung YY, Kim DS, Kim SH, Yuk HJ.
-
Antioxidants (Basel). 2025 Sep 24;14(10):1157. doi: 10.3390/antiox14101157.
2025/10/29
Ferroptosis: The Initiation Process of Lipid Peroxidation in Muscle Food
Kanner J, Shpaizer A, Tirosh O.
-
Biomedicines. 2025 Oct 16;13(10):2528. doi: 10.3390/biomedicines13102528.
2025/10/29
Interference-Free Measurement of Urinary Angiotensin-Converting Enzyme (ACE) Activity: Diagnostic and Therapeutic Monitoring Implications
Szabó AÁ, Enyedi EE, Pintér TB, Mányiné IS, Váradi C, Bányai E, Tóth A, Papp Z, Fagyas M.
-
Biomedicines. 2025 Oct 10;13(10):2469. doi: 10.3390/biomedicines13102469.
2025/10/29
Uncovering Nonlinear Predictors of Serum Biomarker Uric Acid Using Interpretable Machine Learning in Healthy Men
Yang CC, Shen MC, Lai ZY, Ke JC, Chu TW, Chuang YJ.
-
Dtsch Med Wochenschr. 2025 Nov;150(22):1367-1373. doi: 10.1055/a-2180-8346. Epub 2025 Oct 28.
2025/10/29
[News about gout]
Tausche AK.
-
Eur J Prev Cardiol. 2025 Oct 29:zwaf696. doi: 10.1093/eurjpc/zwaf696. Online ahead of print.
2025/10/29
Allopurinol, gout and cardiovascular risk
Jannink J, Mosterd A, Fiolet ATL.
-
Toxics. 2025 Oct 19;13(10):896. doi: 10.3390/toxics13100896.
2025/10/28
Thymoquinone Protective Effect Against Mercury-Induced Reproductive Derangement in Rats: In Vivo and In Silico Investigation
Owumi S, Otunla M, Akindipe P, Arunsi U, Babalola JO, Irozuru CE, Altayyar A, Oluwawibe B, Owoeye O, Oyelere AK.
-
Asian Pac J Cancer Prev. 2025 Oct 1;26(10):3599-3602. doi: 10.31557/APJCP.2025.26.10.3599.
2025/10/28
Molybdenum Deficiency among Esophageal Cancer Patients
Akhter M, Parry AH, Dar AW, Gadda IR.
-
Ther Adv Musculoskelet Dis. 2025 Oct 21;17:1759720X251384584. doi: 10.1177/1759720X251384584. eCollection 2025.
2025/10/28
Gout therapy updated
McCarty KL, Gaffo AL, Diaz-Torne C.
-
BMC Cardiovasc Disord. 2025 Oct 27;25(1):772. doi: 10.1186/s12872-025-05157-x.
2025/10/28
Using unsupervised machine learning methods to cluster cardio-metabolic profile of the middle-aged and elderly Chinese with general and central obesity
Xue Y, Song M, Ung COL, Hu H.
-
Front Endocrinol (Lausanne). 2025 Oct 10;16:1599028. doi: 10.3389/fendo.2025.1599028. eCollection 2025.
2025/10/27
Establishment and evaluation of a model for clinical feature selection and prediction in gout patients with cardiovascular diseases: a retrospective cohort study
Fan B, Ye Y, Wang Z, Xu Y, Lu M, Cong W, Ma F.
-
Phytochemistry. 2025 Oct 23;242:114711. doi: 10.1016/j.phytochem.2025.114711. Online ahead of print.
2025/10/26
Challenges in chiral discrimination at the H-2 and H-10 positions of dihydrobenzofuran from Artemisiacapillaris
Chen J, Ren M, Huang L, Lou Y, Hou X, Zhang Y, Huang G, Cao J.
-
Medicine (Baltimore). 2025 Oct 24;104(43):e45023. doi: 10.1097/MD.0000000000045023.
2025/10/25
Association of single-nucleotide polymorphisms in SLC2A9, SLC22A12 and SLC22A11 genes with hyperuricemia in the Chinese Tibetan population
Li RX, Guo YN, Wang J, Luo B, Danzen G, Zhang T.
-
Pathophysiology. 2025 Sep 23;32(4):49. doi: 10.3390/pathophysiology32040049.
2025/10/24
Cocoa Shell Extract Restores Redox Balance in Developmental Hypertension in Male Rats: Roles of Nrf2, SOD2 and p-eNOS
Ruvira S, Rodríguez-Rodríguez P, Iampanichakul M, Cuquerella LG, Ramiro-Cortijo D, Arribas SM.
-
Womens Health Rep (New Rochelle). 2025 Sep 17;6(1):888-898. doi: 10.1177/26884844251379364. eCollection 2025.
2025/10/24
Gender Differences in the Associations Between Serum Urate and Cardiometabolic Risk Factors in Age-Matched Middle-Aged Japanese
Wakabayashi I, Daimon T, Yamamoto T.
-
J Clin Lipidol. 2025 Sep 26:S1933-2874(25)00419-2. doi: 10.1016/j.jacl.2025.09.033. Online ahead of print.
2025/10/24
Clinical implementation of bempedoic acid in blood lipid management: Real-world data from an Italian lipid clinic
Pavanello C, Cincotto G, Mombelli GG, Castiglione S, Santolamazza C, Calabresi L, Sirtori CR, Alberti A.
-
Joint Bone Spine. 2025 Oct 21:105993. doi: 10.1016/j.jbspin.2025.105993. Online ahead of print.
2025/10/24
Connecting the Dots: Gouty Arthritis, Clonal Haematopoiesis and Myeloid Activation, in a Unified Inflammation Model for Atherosclerosis Progression
Inkum F, Geng X, Terkeltaub R, Cobo I.
-
Talanta. 2025 Oct 10;298(Pt B):128976. doi: 10.1016/j.talanta.2025.128976. Online ahead of print.
2025/10/24
Rapid prediction the dual-enzyme activity of green Vc-ZnCu-MOFs by near-infrared spectroscopy and in vitro study of xanthine oxidase inhibition
Duan X, Tian F, Chu G.
-
Front Endocrinol (Lausanne). 2025 Oct 7;16:1667929. doi: 10.3389/fendo.2025.1667929. eCollection 2025.
2025/10/23
Impact of serum uric acid to high-density lipoprotein cholesterol ratio on short-term outcomes in acute decompensated heart failure: a cohort study in Jiangxi Province, China
Lu Z, Jian G, Jiang K, He S, Wang Z, Wang J, Lan H, Sheng G, Zou Y, Zhang S.
-
Front Nutr. 2025 Oct 7;12:1651214. doi: 10.3389/fnut.2025.1651214. eCollection 2025.
2025/10/23
Lactobacillus paracasei N1115 alleviates hyperuricemia in mice: regulation of uric acid metabolism as well as its impact on gut microbiota and short-chain fatty acids
Zhang H, Wang D, Li D, Bao B, Chen Q, Wang S, Han S, Zhao M.
-
Inflamm Bowel Dis. 2025 Oct 22:izaf231. doi: 10.1093/ibd/izaf231. Online ahead of print.
2025/10/22
Xanthine Oxidase-Dependent Activation of NLPR3 Inflammasome in Epithelial Cells Sustains Inflammation in Inflammatory Bowel Disease
Di Petrillo A, Fais A, Raho N, Era B, Cannea FB, Padiglia A, Grecu E, Murtas D, Maxia C, Sogos V, Porcedda C, Caboni P, Demurtas M, Favale A, Onali S, Fantini MC.
-
Front Nutr. 2025 Oct 6;12:1660317. doi: 10.3389/fnut.2025.1660317. eCollection 2025.
2025/10/22
The role of insulin resistance in the relationship between uric acid and the severity of coronary artery disease: evidence from real-world data
Chen Z, Shang L, Wang M, He L.
-
Cureus. 2025 Sep 19;17(9):e92700. doi: 10.7759/cureus.92700. eCollection 2025 Sep.
2025/10/21
From Purines to Plaques: Serum Uric Acid as a Cardiometabolic Marker and Its Correlation With Dyslipidemia in Essential Hypertension
Suyambulingam A, K A, Venkatesan A, Jayakaran V, Mathisha EP.
-
Front Endocrinol (Lausanne). 2025 Oct 2;16:1655502. doi: 10.3389/fendo.2025.1655502. eCollection 2025.
2025/10/20
Switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, may substantially reduce serum urate levels, through URAT1 inhibition, potentially without adversely affecting ABCG2 function: findings from the SWITCH SURI study
Osonoi T, Shirabe S, Saito M, Hosoya M, Watahiki N, Douguchi S, Ofuchi K, Katoh M.
-
Methodist Debakey Cardiovasc J. 2025 Oct 16;21(1):96-99. doi: 10.14797/mdcvj.1678. eCollection 2025.
2025/10/20
Infective Endocarditis Involving the Chiari Network
Jadvani D, Rana A, Xu J.
-
Clin Drug Investig. 2025 Oct 19. doi: 10.1007/s40261-025-01496-x. Online ahead of print.
2025/10/20
A Single- and Multiple-Dose Study to Characterize the Pharmacokinetics and Safety of Dotinurad in Healthy Chinese Adults
Liu Y, Chen Q, Sun H, Cai C, Kawamura K, Kokan R, Nomoto M.
-
Eur J Intern Med. 2025 Oct 18:106554. doi: 10.1016/j.ejim.2025.106554. Online ahead of print.
2025/10/20
Crystal clear - Part II: the role of uric acid in cardiorenal disease
Borghi C, Fogacci F, Cicero AF.
-
Diabetes Res Clin Pract. 2025 Nov;229:112947. doi: 10.1016/j.diabres.2025.112947. Epub 2025 Oct 17.
2025/10/20
Urate-lowering therapy and risk of cardiorenal mortality in patients with type 2 diabetes and asymptomatic hyperuricemia
Chuan CF, Hwang SJ, Huang YB.
-
Chem Biol Interact. 2025 Oct 16;421:111783. doi: 10.1016/j.cbi.2025.111783. Online ahead of print.
2025/10/19
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats
Yu Q, Liao H, Tan W, Xu L, Lin G, Ai Z, Xie Q, Liu Y, Li Y, Yang X, Su Z, Ma G, Xie J, Lai Z.
-
Chem Biodivers. 2025 Oct 18:e02210. doi: 10.1002/cbdv.202502210. Online ahead of print.
2025/10/18
Essential Oils From Bougainvillea glabra Stem Barks and Leaves: Chemical Profile, Biological Activity, and Computational Approaches
Thanh MP, Minh PH, Pham TV, Huong NT, Ha NX, Son NT.
-
Auton Neurosci. 2025 Oct 14;262:103355. doi: 10.1016/j.autneu.2025.103355. Online ahead of print.
2025/10/18
Aging impairs urethral function in male rats: Increased outlet resistance and oxidative stress
Alexandre EC, Curiel AA, Dias JM, da Silva FH, Antunes E, de Oliveira MG.
-
Acta Physiol (Oxf). 2025 Nov;241(11):e70120. doi: 10.1111/apha.70120.
2025/10/17
Cardiomyocyte-Specific Deletion of Sirtuin 5 Accelerates the Development of Heart Failure Upon Dysregulating Purine Metabolism
Byrne NJ, Koentges C, Pfeil K, Lueg JC, Bakshi S, Tarkhnishvili A, Vosko I, Gollmer J, Birkle LC, Rathner T, Birkle S, Tang S, Rau C, Hoffmann MM, Odening KE, Barnes S, Wilson LS, Ljubojevic-Holzer S, Wallner M, von Lewinski D, Rainer P, Sedej S, Sourij H, Bode C, Wende AR, Zirlik A, Bugger H.
-
Bioorg Chem. 2025 Oct 9;166:109076. doi: 10.1016/j.bioorg.2025.109076. Online ahead of print.
2025/10/17
Design, synthesis, and evaluation of N-substituted indolyl-diazine derivatives as potent xanthine oxidase inhibitors
Li S, Huang D, Zhao Y, Lu W, Luo X, Xu Z, Sun Q, Liu G.
-
Biomed Pharmacother. 2025 Oct 15;192:118629. doi: 10.1016/j.biopha.2025.118629. Online ahead of print.
2025/10/17
Effect of colchicine in heart failure patients with metabolic syndrome: Focus on inflammatory mechanisms
Xu N, Cheng S, Yuan Q.
-
Drug Metab Dispos. 2025 Sep 24;53(11):100169. doi: 10.1016/j.dmd.2025.100169. Online ahead of print.
2025/10/16
Quetiapine competitively inhibits aldehyde oxidase-mediated reduction
Ueda H, Asano S, Narumi K, Aoyagi R, Okamoto K, Kobayashi M.
-
J Physiol. 2025 Oct 16. doi: 10.1113/JP289678. Online ahead of print.
2025/10/16
Angiotensin-converting enzyme 2 regulates the placental response to repeated hypoxia-reoxygenation insult
Brooker IA, Sutherland JM, Endacott SK, Lumbers ER, Fisher JJ, Pringle KG.
-
J Pediatr Endocrinol Metab. 2025 Oct 17. doi: 10.1515/jpem-2025-0213. Online ahead of print.
2025/10/16
Maturity-onset diabetes of the young due to HNF1β variants (HNF1β-MODY): a 2-year follow-up study of six patients from a single diabetes center
Jiang H, Luo Y, Huang X, Wu H, Shan X.
-
Foods. 2025 Oct 1;14(19):3404. doi: 10.3390/foods14193404.
2025/10/16
Inhibition of Xanthine Oxidase by Four Phenolic Acids: Kinetic, Spectroscopic, Molecular Simulation, and Cellular Insights
Wang X, Su D, Luo X, Chen B, Bhullar KS, Liu H, Wang C, Zhang J, Wang L, Yang H, Zhou W.
-
Foods. 2025 Sep 30;14(19):3396. doi: 10.3390/foods14193396.
2025/10/16
The Molecular Mechanism of Polysaccharides from Polygonatum cyrtonema Hua in Improving Hyperuricemia by Regulating Key Targets of Uric Acid Metabolism in Mice
Pu S, Gong J, Sun M, Hu Z, Wu Z.
-
Molecules. 2025 Oct 1;30(19):3936. doi: 10.3390/molecules30193936.
2025/10/16
Impact of Artemisia selengensis Turcz. Leaf Extract on Beer Brewing: Fermentation Dynamics, Flavor Compounds and Hypolipidemic/Antihyperuricemic Effects
Li Z, Zhou J, Ye C, Yang J, Zeng C.
-
Molecules. 2025 Sep 28;30(19):3914. doi: 10.3390/molecules30193914.
2025/10/16
Tiliroside Suppresses Uric Acid Production in Hepatocytes and Attenuates Purine-Induced Hyperuricemia in Male ICR Mice
Adachi SI, Kondo S, Sato Y, Yoshizawa F, Yagasaki K.
-
Int J Mol Sci. 2025 Oct 7;26(19):9758. doi: 10.3390/ijms26199758.
2025/10/16
Atherosclerotic Plaque Crystals Induce Endothelial Dysfunction
Thazhathveettil J, Gomez SA, Olaoseeji D, Wu R, Sirsjö A, Paramel GV.
-
J Clin Med. 2025 Sep 25;14(19):6782. doi: 10.3390/jcm14196782.
2025/10/16
Fetuin-A Concentration in the Perinatal Period and Maternal BMI Dynamics During Pregnancy, Labor, and Early Postpartum: Is ΔBMI a Parameter Worth Considering?
Obuchowska-Standyło A, Kimber-Trojnar Ż, Czuba M, Trojnar K, Leszczyńska-Gorzelak B.
-
Ren Fail. 2025 Dec;47(1):2572360. doi: 10.1080/0886022X.2025.2572360. Epub 2025 Oct 15.
2025/10/16
Nomogram for predicting acute kidney injury after primary PCI in STEMI patients: development and validation study
Li X, Yan J, Chen Y, Zhang X.

